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chloroquine and Tuberculosis

chloroquine has been researched along with Tuberculosis in 13 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Tuberculosis: Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM TUBERCULOSIS.

Research Excerpts

ExcerptRelevanceReference
"The immune response of 198 young Nigerian children protected against malaria by chemoprophylaxis with chloroquine to immunization with triple, poliomyelitis, measles, typhoid, meningococcal and BCG vaccines was compared with the immune response to vaccination of 185 control children."9.05Malaria chemoprophylaxis with chloroquine in young Nigerian children. II. Effect on the immune response to vaccination. ( Bartlett, A; Bidwell, DE; Bradley, AK; Bradley-Moore, AM; Craske, J; Gilles, HM; Greenwood, BM; Kirkwood, BR; Voller, A, 1985)
"The immune response of 198 young Nigerian children protected against malaria by chemoprophylaxis with chloroquine to immunization with triple, poliomyelitis, measles, typhoid, meningococcal and BCG vaccines was compared with the immune response to vaccination of 185 control children."5.05Malaria chemoprophylaxis with chloroquine in young Nigerian children. II. Effect on the immune response to vaccination. ( Bartlett, A; Bidwell, DE; Bradley, AK; Bradley-Moore, AM; Craske, J; Gilles, HM; Greenwood, BM; Kirkwood, BR; Voller, A, 1985)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's2 (15.38)18.2507
2000's1 (7.69)29.6817
2010's2 (15.38)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Karad, SC1
Purohit, VB1
Thakor, P1
Thakkar, VR1
Raval, DK1
Gaikwad, VR1
Karale, UB1
Govindarajalu, G1
Adhikari, N1
Krishna, EV1
Krishna, VS1
Misra, S1
Sriram, D1
Sijwali, PS1
Rode, HB1
Mishra, R1
Kohli, S1
Malhotra, N1
Bandyopadhyay, P1
Mehta, M1
Munshi, M1
Adiga, V1
Ahuja, VK1
Shandil, RK1
Rajmani, RS1
Seshasayee, ASN1
Singh, A1
PFAFFENBERG, R1
Lewinsohn, DM1
Alderson, MR1
Briden, AL1
Riddell, SR1
Reed, SG1
Grabstein, KH1
Bastien, P1
Bradley-Moore, AM1
Greenwood, BM1
Bradley, AK1
Bartlett, A1
Bidwell, DE1
Voller, A1
Craske, J1
Kirkwood, BR1
Gilles, HM1
Geddes, AM1
Woodruff, AW1
Vischer, WA1
Havel, A1
Rosenfeld, M1
Simpson, GV1

Trials

1 trial available for chloroquine and Tuberculosis

ArticleYear
Malaria chemoprophylaxis with chloroquine in young Nigerian children. II. Effect on the immune response to vaccination.
    Annals of tropical medicine and parasitology, 1985, Volume: 79, Issue:6

    Topics: Antibody Formation; BCG Vaccine; Child, Preschool; Chloroquine; Diphtheria; Humans; Immunity, Cellul

1985

Other Studies

12 other studies available for chloroquine and Tuberculosis

ArticleYear
Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities.
    European journal of medicinal chemistry, 2016, Apr-13, Volume: 112

    Topics: Anti-Infective Agents; Antimalarials; Antitubercular Agents; Bacteria; Bacterial Infections; Fungi;

2016
Synthesis and efficacy of pyrvinium-inspired analogs against tuberculosis and malaria pathogens.
    Bioorganic & medicinal chemistry letters, 2020, 04-15, Volume: 30, Issue:8

    Topics: Antimalarials; Antitubercular Agents; Dose-Response Relationship, Drug; Malaria, Falciparum; Microbi

2020
Targeting redox heterogeneity to counteract drug tolerance in replicating
    Science translational medicine, 2019, 11-13, Volume: 11, Issue:518

    Topics: Acids; Animals; Antitubercular Agents; Bacterial Proteins; Chloroquine; Cysteine; Drug Interactions;

2019
[On the therapy of rheumatoid arthritis in diabetes tuberculosis].
    Deutsches medizinisches Journal, 1960, Mar-20, Volume: 11

    Topics: Arthritis, Rheumatoid; Chloroquine; Diabetes Complications; Diabetes Mellitus; Humans; Tuberculosis;

1960
Characterization of human CD8+ T cells reactive with Mycobacterium tuberculosis-infected antigen-presenting cells.
    The Journal of experimental medicine, 1998, May-18, Volume: 187, Issue:10

    Topics: Acetylcysteine; Amino Acid Sequence; Animals; Antigen Presentation; CD8-Positive T-Lymphocytes; Chlo

1998
Proceedings of the Second International Conference on HIV and Iron. Brugge, Belgium, March 2000.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2001, Volume: 20, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Animals; Anti-HIV Agents; Chloroquine; HIV Infections; HIV-1;

2001
Public-health epidemiology in Vanuatu.
    The Medical journal of Australia, 1990, Jan-01, Volume: 152, Issue:1

    Topics: Adolescent; Anemia; Animals; Cardiovascular Diseases; Child; Child, Preschool; Chloroquine; Drug Res

1990
Imported infections. Unexplained fever.
    British medical journal, 1974, Nov-16, Volume: 4, Issue:5941

    Topics: Africa; Asia; Brucellosis; Chloramphenicol; Chloroquine; Fever; Humans; Leishmaniasis, Visceral; Liv

1974
Current practice in tropical medicine.
    Transactions of the Medical Society of London, 1969, Volume: 85

    Topics: Acute Kidney Injury; Amebiasis; Amebicides; Chloroquine; Cholera; Drug Resistance, Microbial; Hepati

1969
Antimicrobial activity of the leprostatic drug 3-(p-chloranilino)-10-(p-chlorphenyl-2,10-dihydro-2-(isopropylimino)-phenazine (G 30'320, B. 663).
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:5

    Topics: Animals; Antitubercular Agents; Aspergillosis; Candidiasis; Chloroquine; Cricetinae; Disease Models,

1970
[Inhibition of isoniazid activity in the presence of chloroquinum diphosphoricum].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:9

    Topics: Animals; Body Weight; Chloroquine; Depression, Chemical; Drug Antagonism; Isoniazid; Mice; Mycobacte

1970
Diagnosis and treatment of uveitis in association with sarcoidosis.
    Transactions of the American Ophthalmological Society, 1968, Volume: 66

    Topics: Adrenal Cortex Hormones; Adult; Age Factors; Biopsy; Blood Protein Electrophoresis; Bone and Bones;

1968