chloroquine has been researched along with Tinnitus in 5 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Tinnitus: A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The suggested dose of chloroquine for COVID-19 infection is considerably higher than the usual dosage for malaria treatment; therefore, it is plausible that the ototoxic effects will be greater." | 6.66 | Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review. ( Baguley, DM; Kasbekar, AV; Prayuenyong, P, 2020) |
| "Chloroquine (CQ), a 4-aminoquinoline drug, has been largely used for the treatment of rheumatoid arthritis and other connective tissue diseases." | 4.84 | Chloroquine ototoxicity. ( Bortoli, R; Santiago, M, 2007) |
| " The suggested dose of chloroquine for COVID-19 infection is considerably higher than the usual dosage for malaria treatment; therefore, it is plausible that the ototoxic effects will be greater." | 2.66 | Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review. ( Baguley, DM; Kasbekar, AV; Prayuenyong, P, 2020) |
| "Tinnitus was the first and the predominant symptom in 140 patients (89." | 1.40 | Ototoxicity in Nigeria: why it persists. ( Ahmad, BM; Bakari, A; Kokong, DD, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prayuenyong, P | 1 |
| Kasbekar, AV | 1 |
| Baguley, DM | 1 |
| Kokong, DD | 1 |
| Bakari, A | 1 |
| Ahmad, BM | 1 |
| Bortoli, R | 1 |
| Santiago, M | 1 |
| Cooke, RA | 1 |
| Shannon, J | 1 |
| Dwivedi, GS | 1 |
| Mehra, YN | 1 |
2 reviews available for chloroquine and Tinnitus
| Article | Year |
|---|---|
Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review.
Topics: Antimalarials; Antiviral Agents; Chloroquine; COVID-19 Drug Treatment; Emergencies; Hearing Loss; Hu | 2020 |
Chloroquine ototoxicity.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Cochlea; Hearing; Hearing Loss; Humans; Ti | 2007 |
3 other studies available for chloroquine and Tinnitus
| Article | Year |
|---|---|
Ototoxicity in Nigeria: why it persists.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antimalarials; Audiometry; Child; | 2014 |
Malaria in southeast Queensland in 1979.
Topics: Adolescent; Adult; Australia; Child; Child, Preschool; Chloroquine; Dapsone; Female; Humans; Infant; | 1980 |
Ototoxicity of chloroquine phosphate. A case report.
Topics: Chloroquine; Deafness; Humans; Male; Melanins; Middle Aged; Tinnitus; Vision Disorders | 1978 |