Page last updated: 2024-10-24

chloroquine and Thrombocytopenia

chloroquine has been researched along with Thrombocytopenia in 28 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Thrombocytopenia: A subnormal level of BLOOD PLATELETS.

Research Excerpts

ExcerptRelevanceReference
" He used chloroquine as a malaria prophylaxis during his stay and for 6 weeks after his return to Japan."7.69[A case of Plasmodium ovale malaria with thrombocytopenia and an abnormality grade in FDP concentration despite the use of chloroquine as a malaria prophylaxis]. ( Karino, T; Miyashita, N; Nagatomo, Y; Nakajima, M; Niki, Y; Okimoto, N; Soejima, R; Yoshida, K, 1995)
" knowlesi was again brought to the attention of the medical community when in 2004, Balbir Singh and his co-workers reported that about 58% of malaria cases observed in the Kapit district of the Malaysian Borneo were actually caused by P."4.89Plasmodium knowlesi: the emerging zoonotic malaria parasite. ( Antinori, S; Corbellino, M; Galimberti, L; Milazzo, L, 2013)
" knowlesi infection had uncomplicated malaria that responded to chloroquine and primaquine treatment."3.75Clinical and laboratory features of human Plasmodium knowlesi infection. ( Cox-Singh, J; Daneshvar, C; Davis, TM; Divis, PC; Rafa'ee, MZ; Singh, B; Zakaria, SK, 2009)
" He used chloroquine as a malaria prophylaxis during his stay and for 6 weeks after his return to Japan."3.69[A case of Plasmodium ovale malaria with thrombocytopenia and an abnormality grade in FDP concentration despite the use of chloroquine as a malaria prophylaxis]. ( Karino, T; Miyashita, N; Nagatomo, Y; Nakajima, M; Niki, Y; Okimoto, N; Soejima, R; Yoshida, K, 1995)
" The second patient acquired falciparum malaria inspite of chloroquine prophylaxis and was admitted with a thrombocytopenia of 24 000 mm3."3.66[Think of malaria!]. ( Schreiber, W, 1981)
"The exact treatment of sepsis is still the subject of considerable debate."2.58Sepsis: The Involvement of Platelets and the Current Treatments. ( Ganaes, JOF; Lopes-Pires, ME; Naime, ACA, 2018)
"Cases of human babesiosis are rarely reported and probably under-diagnosed in China; therefore, improving our understanding of this disease as a newly emerging public health threat is imperative."1.48Human babesiosis in Southeast China: A case report. ( Chen, H; Huang, S; Jin, L; Li, J; Ni, Q; Pan, C; Yao, L; Zhang, L, 2018)
"Serum samples of thirty patients with dengue hemorrhagic fever (DHF) were analysed for different biochemical parameters."1.46Potential of Nigella sativa seed aqueous extract in ameliorating quinine-induced thrombocytopenia in rats. ( Khan, MA; Rehman, S; Robin, S; Ruby, T; Saadia, M; Sher, M; Siddiqui, WA, 2017)
"Antiphospholipid syndrome is an autoimmune disease that is characterised by tendency to thrombosis, obstetrical and hematological complications."1.33Nocardiosis in a patient with primary anti-phospholipid syndrome. ( Altinay, G; Ermantaş, N; Okten, O; Oktun, MT; Soy, M; Tunçbilek, N; Turgut, B, 2006)
"vivax malaria were compared with 20, apparently healthy controls."1.31Immunological alterations associated with Plasmodium vivax malaria in South Korea. ( Han, K; Kang, CS; Kim, BK; Kim, M; Kim, Y; Lee, EJ; Lee, HK; Lee, J; Lee, S; Lim, J; Oh, EJ; Oh, J, 2001)
"falciparum."1.30Profound thrombocytopenia in Plasmodium vivax malaria. ( Bhoi, S; Kakar, A; Kakar, S; Prakash, V, 1999)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199010 (35.71)18.7374
1990's4 (14.29)18.2507
2000's5 (17.86)29.6817
2010's8 (28.57)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Thangaraju, P1
Narasimhan, G1
Ramamurthy, VA1
Gurunthalingam, MP1
Yella, SST1
Venkatesan, S1
Thangaraju, E1
Saadia, M1
Rehman, S1
Robin, S1
Ruby, T1
Sher, M1
Siddiqui, WA1
Khan, MA1
Huang, S1
Zhang, L1
Yao, L1
Li, J1
Chen, H1
Ni, Q1
Pan, C1
Jin, L1
Naime, ACA1
Ganaes, JOF1
Lopes-Pires, ME1
Laothamatas, J1
Sammet, CL1
Golay, X1
Van Cauteren, M1
Lekprasert, V1
Tangpukdee, N1
Krudsood, S1
Leowattana, W1
Wilairatana, P1
Swaminathan, SV1
DeLaPaz, RL1
Brown, TR1
Looareesuwan, S1
Brittenham, GM1
Dos-Santos, JC1
Angerami, RN1
Castiñeiras, CM1
Lopes, SC1
Albrecht, L1
Garcia, MT1
Levy, CE1
Moretti, ML1
Lacerda, MV1
Costa, FT1
Zaki, S1
Daneshvar, C1
Davis, TM1
Cox-Singh, J1
Rafa'ee, MZ1
Zakaria, SK1
Divis, PC1
Singh, B1
Altman, A1
Gueta, I1
Grosman, T1
Schwartz, E1
Barber, BE1
William, T1
Jikal, M1
Jilip, J1
Dhararaj, P1
Menon, J1
Yeo, TW1
Anstey, NM1
Antinori, S1
Galimberti, L1
Milazzo, L1
Corbellino, M1
NIEWEG, HO1
BOUMA, HG1
SOEPARMAN, R1
ABELS, J1
KUPCHINSKAS, IuK1
Soy, M1
Oktun, MT1
Tunçbilek, N1
Ermantaş, N1
Okten, O1
Altinay, G1
Turgut, B1
Neri, S1
Pulvirenti, D1
Patamia, I1
Zoccolo, A1
Castellino, P1
Harris, LF1
Shasteen, WJ1
Lampert, R1
Schreiber, W1
Miyashita, N1
Karino, T1
Nagatomo, Y1
Yoshida, K1
Nakajima, M1
Okimoto, N1
Niki, Y1
Soejima, R1
Suarez, IM1
Diaz, RA1
Aguayo Canela, D1
Pujol de la Llave, E1
Lown, JA1
Ivey, JG1
Kakar, A1
Bhoi, S1
Prakash, V1
Kakar, S1
Lee, HK1
Lim, J1
Kim, M1
Lee, S1
Oh, EJ1
Lee, J1
Oh, J1
Kim, Y1
Han, K1
Lee, EJ1
Kang, CS1
Kim, BK1
Muirden, KD1
Metcalfe, P1
Minchinton, RM1
Murphy, MF1
Waters, AH1
Campbell, CH1
Holiday, J1
Biggs, JC1
Backhouse, TC1
Eales, L1
Sheehy, TW1
Reba, RC1
Parks, GR1
Martelo, OJ1
Smoller, M1
Saladin, TA1

Reviews

4 reviews available for chloroquine and Thrombocytopenia

ArticleYear
Sepsis: The Involvement of Platelets and the Current Treatments.
    Current molecular pharmacology, 2018, Volume: 11, Issue:4

    Topics: Acetylcysteine; Animals; Blood Platelets; Capsaicin; Chloroquine; Disseminated Intravascular Coagula

2018
Plasmodium knowlesi: the emerging zoonotic malaria parasite.
    Acta tropica, 2013, Volume: 125, Issue:2

    Topics: Animals; Anopheles; Antimalarials; Borneo; Chloroquine; Communicable Diseases, Emerging; Geography;

2013
[AUTOALLERGY IN CLINICAL INTERNAL MEDICINE].
    Klinicheskaia meditsina, 1964, Volume: 42

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Agranulocytosis; Anemia, Hemolytic; Anemia, He

1964
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
    The Medical journal of Australia, 1986, Jan-06, Volume: 144, Issue:1

    Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T

1986

Trials

1 trial available for chloroquine and Thrombocytopenia

ArticleYear
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
    The Medical journal of Australia, 1986, Jan-06, Volume: 144, Issue:1

    Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T

1986

Other Studies

24 other studies available for chloroquine and Thrombocytopenia

ArticleYear
Molecular Docking Analysis of
    Infectious disorders drug targets, 2023, Volume: 23, Issue:1

    Topics: Chloroquine; Dengue; Humans; Justicia; Molecular Docking Simulation; Plant Preparations; Receptors,

2023
Potential of Nigella sativa seed aqueous extract in ameliorating quinine-induced thrombocytopenia in rats.
    Pakistan journal of pharmaceutical sciences, 2017, Volume: 30, Issue:5

    Topics: Adolescent; Adult; Animals; Antioxidants; Blood Platelets; Case-Control Studies; Chloroquine; Diseas

2017
Human babesiosis in Southeast China: A case report.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2018, Volume: 68

    Topics: Administration, Intravenous; Anemia, Hemolytic; Anti-Bacterial Agents; Azithromycin; Babesiosis; C-R

2018
Transient lesion in the splenium of the corpus callosum in acute uncomplicated falciparum malaria.
    The American journal of tropical medicine and hygiene, 2014, Volume: 90, Issue:6

    Topics: Acute Disease; Adult; Antimalarials; Artemisinins; Chloroquine; Corpus Callosum; Drug Therapy, Combi

2014
Imported malaria in a non-endemic area: the experience of the university of Campinas hospital in the Brazilian Southeast.
    Malaria journal, 2014, Jul-22, Volume: 13

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Anemia; Antimalarials; Artemether; Artemisini

2014
Chloroquine resistance vivax malaria in an infant: a report from India.
    Journal of vector borne diseases, 2009, Volume: 46, Issue:2

    Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; India; Infant, Newborn; Malaria

2009
Clinical and laboratory features of human Plasmodium knowlesi infection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009, Sep-15, Volume: 49, Issue:6

    Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Blood Chemical Analysis; Chloroquine; Female; Hemog

2009
[Acute respiratory distress syndrome (ARDS) as a complication of malaria P.vivax].
    Harefuah, 2010, Volume: 149, Issue:9

    Topics: Aged; Antimalarials; Chloroquine; Female; Humans; India; Leukopenia; Malaria, Vivax; Male; Plasmodiu

2010
Plasmodium knowlesi malaria in children.
    Emerging infectious diseases, 2011, Volume: 17, Issue:5

    Topics: Adolescent; Age Factors; Anemia; Antimalarials; Child; Child, Preschool; Chloroquine; Female; Humans

2011
[CLINICAL STUDY ON CHANGES IN THE BLOOD CAUSED BY DRUGS].
    Nederlands tijdschrift voor geneeskunde, 1963, Nov-09, Volume: 107

    Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Blood Platelet Disorders; Chloramphenicol; Chloroquine;

1963
Nocardiosis in a patient with primary anti-phospholipid syndrome.
    Rheumatology international, 2006, Volume: 26, Issue:5

    Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Antiphospholipid Syndrome; Antirheumatic Age

2006
Acute renal failure in Plasmodium malariae infection.
    The Netherlands journal of medicine, 2008, Volume: 66, Issue:4

    Topics: Acute Kidney Injury; Adult; Animals; Antimalarials; Chloroquine; Female; Humans; Liver Failure; Mala

2008
Malaria: recent experience in a community.
    Southern medical journal, 1984, Volume: 77, Issue:9

    Topics: Adolescent; Adult; Alabama; Anemia; Child; Child, Preschool; Chloroquine; Drug Resistance, Microbial

1984
[Think of malaria!].
    Fortschritte der Medizin, 1981, Jan-29, Volume: 99, Issue:4

    Topics: Adult; Chloroquine; Humans; Lung Abscess; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; Th

1981
[A case of Plasmodium ovale malaria with thrombocytopenia and an abnormality grade in FDP concentration despite the use of chloroquine as a malaria prophylaxis].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1995, Volume: 69, Issue:4

    Topics: Animals; Chloroquine; Fibrin Fibrinogen Degradation Products; Humans; Malaria; Male; Middle Aged; Pl

1995
Correction of severe thrombocytopenia with chloroquine in the primary antiphospholipid syndrome.
    Lupus, 1996, Volume: 5, Issue:1

    Topics: Adult; Antiphospholipid Syndrome; Antirheumatic Agents; Chloroquine; Female; Follow-Up Studies; Huma

1996
Evaluation of a solid phase red cell adherence technique for platelet antibody screening.
    Transfusion medicine (Oxford, England), 1991, Volume: 1, Issue:3

    Topics: Antigens, Human Platelet; Autoantibodies; Blood Platelets; Cell Adhesion; Chloroquine; Erythrocytes;

1991
Profound thrombocytopenia in Plasmodium vivax malaria.
    Diagnostic microbiology and infectious disease, 1999, Volume: 35, Issue:3

    Topics: Adult; Antimalarials; Chloroquine; Drug Therapy, Combination; Female; Humans; Malaria, Vivax; Platel

1999
Immunological alterations associated with Plasmodium vivax malaria in South Korea.
    Annals of tropical medicine and parasitology, 2001, Volume: 95, Issue:1

    Topics: Adolescent; Adult; Antimalarials; Biomarkers; Case-Control Studies; Chloroquine; Eosinophils; Female

2001
Use of chloroquine-treated granulocytes and platelets in the diagnosis of immune cytopenias.
    Vox sanguinis, 1985, Volume: 49, Issue:5

    Topics: Adult; Antibodies; Autoantibodies; Autoimmune Diseases; Blood Platelets; Chloroquine; Female; Fever;

1985
Chloroquine-resistant Falciparum malaria acquired in Vietnam.
    The Medical journal of Australia, 1973, Oct-13, Volume: 2, Issue:15

    Topics: Acute Kidney Injury; Adolescent; Adult; Blood Cell Count; Chloroquine; Dapsone; Drug Resistance, Mic

1973
Acute falciparum malaria. Complications and treatment.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Jul-06, Volume: 48, Issue:32

    Topics: Acute Kidney Injury; Brain Diseases; Chloroquine; Coma; Disseminated Intravascular Coagulation; Hepa

1974
Combined pyrimethamine-quinine therapy for chloroquine-resistant P. falciparum infections.
    Southern medical journal, 1969, Volume: 62, Issue:2

    Topics: Adolescent; Adult; Agranulocytosis; Anemia, Hemolytic; Chloroquine; Clinical Laboratory Techniques;

1969
Malaria in American soldiers.
    Archives of internal medicine, 1969, Volume: 123, Issue:4

    Topics: Anemia, Hemolytic; Blood Cell Count; Carrier State; Chloroquine; Hematocrit; Hemoglobinometry; Hepat

1969