Page last updated: 2024-10-24

chloroquine and Tachycardia, Ventricular

chloroquine has been researched along with Tachycardia, Ventricular in 2 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).

Research Excerpts

ExcerptRelevanceReference
"Atrial and ventricular tachyarrhythmias can be perpetuated by up-regulation of inward rectifier potassium channels."1.36Specific residues of the cytoplasmic domains of cardiac inward rectifier potassium channels are effective antifibrillatory targets. ( Berenfeld, O; Calvo, CJ; Chapula, JA; Ferrer-Villada, T; Grzeda, KR; Jalife, J; López-Izquierdo, A; Noujaim, SF; Pandit, S; Ponce-Balbuena, D; Stuckey, JA, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Kaagaard, MD1
Matos, LO1
Holm, AE1
Gomes, LC1
Wegener, A1
Lima, KO1
Vieira, IVM1
de Souza, RM1
Marinho, CRF1
Hviid, L1
Vestergaard, LS1
Dominguez, H1
Biering-Sørensen, T1
Silvestre, OM1
Brainin, P1
Noujaim, SF1
Stuckey, JA1
Ponce-Balbuena, D1
Ferrer-Villada, T1
López-Izquierdo, A1
Pandit, S1
Calvo, CJ1
Grzeda, KR1
Berenfeld, O1
Chapula, JA1
Jalife, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Malaria Heart Disease Study: A Novel Pathway to Subclinical Heart Disease[NCT04445103]597 participants (Actual)Observational2020-06-21Terminated (stopped due to Due to the COVID-19 pandemic it was not possible to complete the study inclusion as originally anticipated.)
Chloroquine for Patients With Symptomatic Persistent Atrial Fibrillation: A Prospective Pilot Study[NCT02932007]Phase 240 participants (Anticipated)Interventional2017-03-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for chloroquine and Tachycardia, Ventricular

ArticleYear
Frequency of Electrocardiographic Alterations and Pericardial Effusion in Patients With Uncomplicated Malaria.
    The American journal of cardiology, 2022, 02-15, Volume: 165

    Topics: Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Brazil; Case-Control Studies; Chlor

2022
Specific residues of the cytoplasmic domains of cardiac inward rectifier potassium channels are effective antifibrillatory targets.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2010, Volume: 24, Issue:11

    Topics: Animals; Anti-Arrhythmia Agents; Chloroquine; Cytoplasm; Heart; Mice; Models, Molecular; Potassium C

2010