chloroquine has been researched along with Syndrome in 27 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine induced a myasthenic syndrome in a patient taking the drug for presumable reticular erythematous mucinosis." | 8.77 | Myasthenic syndrome caused by direct effect of chloroquine on neuromuscular junction. ( Bednarik, J; Bourgeois, P; Carton, H; Robberecht, W; van Hees, J, 1989) |
| "Chloroquine is considered essentially nontoxic when used for the chemosuppression of malaria, but gastrointestinal upsets, headache, blurring of vision, pruritus, and uritcaria may occur during chloroquine therapy." | 7.66 | Extrapyramidal syndrome following chloroquine therapy. ( Singh, M; Singhi, P; Singhi, S, 1979) |
| "Treatment of a six-year-old boy with porphyria congenita (Günther) by small amounts of chloroquine was followed by a sharp but transient increase of the urinary excretion of porphyrins." | 7.66 | [Porphyria erythropoietica congenita Günther and chloroquine (author's transl)]. ( Ippen, H; Seubert, A; Seubert, S; Tillmann, W, 1978) |
| "Chloroquine induced a myasthenic syndrome in a patient taking the drug for presumable reticular erythematous mucinosis." | 4.77 | Myasthenic syndrome caused by direct effect of chloroquine on neuromuscular junction. ( Bednarik, J; Bourgeois, P; Carton, H; Robberecht, W; van Hees, J, 1989) |
| "Chloroquine is considered essentially nontoxic when used for the chemosuppression of malaria, but gastrointestinal upsets, headache, blurring of vision, pruritus, and uritcaria may occur during chloroquine therapy." | 3.66 | Extrapyramidal syndrome following chloroquine therapy. ( Singh, M; Singhi, P; Singhi, S, 1979) |
| "Treatment of a six-year-old boy with porphyria congenita (Günther) by small amounts of chloroquine was followed by a sharp but transient increase of the urinary excretion of porphyrins." | 3.66 | [Porphyria erythropoietica congenita Günther and chloroquine (author's transl)]. ( Ippen, H; Seubert, A; Seubert, S; Tillmann, W, 1978) |
| "Chloroquine treatment and other manipulations that produce chromatin defects in the absence of detectable double strand breaks also trigger ATM phosphorylation and the phosphorylation of p53 in primary human fibroblasts, while other downstream substrates of ATM that are involved in the repair of DNA double strand breaks remain unphosphorylated." | 1.33 | Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with ICF syndrome without downstream kinase activity. ( Gamo, K; Gartler, SM; Gatti, RA; Goldstine, JV; Hansen, RS; Marahrens, Y; Nahas, S; Roelfsema, JH, 2006) |
| "Thirteen cases of malaria are presented for their protean manifestations." | 1.29 | Protean manifestations of malaria--(multi organ dysfunction syndrome). ( Gaikwad, A; Jirwankar, PS; Talib, SH, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (74.07) | 18.7374 |
| 1990's | 3 (11.11) | 18.2507 |
| 2000's | 4 (14.81) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KRAUS, KA | 1 |
| KOLL, JF | 1 |
| BUTTERWORTH, RF | 1 |
| Goldstine, JV | 1 |
| Nahas, S | 1 |
| Gamo, K | 1 |
| Gartler, SM | 1 |
| Hansen, RS | 1 |
| Roelfsema, JH | 1 |
| Gatti, RA | 1 |
| Marahrens, Y | 1 |
| Hoffman, SL | 1 |
| Piessens, WF | 1 |
| Ratiwayanto, S | 1 |
| Hussein, PR | 1 |
| Kurniawan, L | 1 |
| Piessens, PW | 1 |
| Campbell, JR | 1 |
| Marwoto, HA | 1 |
| Oravisto, KJ | 1 |
| Claudy, AL | 1 |
| Talib, SH | 1 |
| Gaikwad, A | 1 |
| Jirwankar, PS | 1 |
| Kozyraki, R | 1 |
| Fyfe, J | 1 |
| Kristiansen, M | 1 |
| Gerdes, C | 1 |
| Jacobsen, C | 1 |
| Cui, S | 1 |
| Christensen, EI | 1 |
| Aminoff, M | 1 |
| de la Chapelle, A | 1 |
| Krahe, R | 1 |
| Verroust, PJ | 1 |
| Moestrup, SK | 1 |
| Van den Ende, J | 1 |
| van Gompel, A | 1 |
| van den Enden, E | 1 |
| Taelman, H | 1 |
| Vanham, G | 1 |
| Vervoort, T | 1 |
| Seneviratne, U | 1 |
| Gamage, R | 1 |
| Climent-Albaladejo, A | 1 |
| Saiz-Cuenca, E | 1 |
| Rosique-Roman, J | 1 |
| Caballero-Rodriguez, J | 1 |
| Galvez-Munoz, J | 1 |
| Wurm, K | 1 |
| Argov, Z | 1 |
| Mastaglia, FL | 1 |
| Singhi, S | 1 |
| Singhi, P | 1 |
| Singh, M | 1 |
| Putintsev, VI | 1 |
| Son, EA | 1 |
| Ippen, H | 1 |
| Tillmann, W | 1 |
| Seubert, S | 1 |
| Seubert, A | 1 |
| Ricken, D | 1 |
| Flenker, I | 1 |
| James, DG | 1 |
| Neville, E | 1 |
| Langley, DA | 1 |
| Betticher, DC | 1 |
| Nicole, A | 1 |
| Pugin, P | 1 |
| Regamey, C | 1 |
| Robberecht, W | 1 |
| Bednarik, J | 1 |
| Bourgeois, P | 1 |
| van Hees, J | 1 |
| Carton, H | 1 |
| Gupta, OP | 1 |
| Bajaj, S | 1 |
| Gupta, SC | 1 |
| Tomec, RJ | 1 |
| Walsh, M | 1 |
| Garcia, JC | 1 |
| Jordan, PK | 1 |
| Gupta, HL | 1 |
| Vankataswar, N | 1 |
| Aggarwal, A | 1 |
| Bhutani, P | 1 |
| Haber, RM | 1 |
| Hanna, W | 1 |
| Ramsay, CA | 1 |
| Boxall, LB | 1 |
| Daynes, WG | 1 |
| Karaca, M | 1 |
| Akoğuz, O | 1 |
| Bölükoğlu, B | 1 |
| Meadows, SP | 1 |
5 reviews available for chloroquine and Syndrome
| Article | Year |
|---|---|
Interstitial cystitis as an autoimmune disease. A review.
Topics: Adult; Animals; Antibodies, Antinuclear; Antibody Specificity; Autoimmune Diseases; Azathioprine; Ch | 1980 |
[Sarcoidosis therapy and its problems today].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Anti-Inflammatory Agents; Antineoplasti | 1978 |
Drug therapy: Disorders of neuromuscular transmission caused by drugs.
Topics: Aged; Animals; Anti-Bacterial Agents; Anticonvulsants; Cardiovascular Agents; Chloroquine; Drug-Rela | 1979 |
Myasthenic syndrome caused by direct effect of chloroquine on neuromuscular junction.
Topics: Adult; Chloroquine; Electric Stimulation; Electromyography; Erythema; Female; Humans; Injections; Ma | 1989 |
Hereditary epidermolysis bullosa.
Topics: Adult; Animals; Child; Child, Preschool; Chloroquine; Dogs; Epidermolysis Bullosa; Female; Humans; I | 1985 |
22 other studies available for chloroquine and Syndrome
| Article | Year |
|---|---|
[Report on experiences with elestol therapy of rheumatic syndromes].
Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Chloroquine; Humans; Prednisone; Spondylitis; Spondylitis | 1959 |
The burning skin syndrome: treatment with hydroxychloroquine.
Topics: Chloroquine; Dermatology; Humans; Hydroxychloroquine; Musculoskeletal Diseases; Pain; Paresthesia; S | 1960 |
Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with ICF syndrome without downstream kinase activity.
Topics: Abnormalities, Multiple; Androstadienes; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cy | 2006 |
Reduction of suppressor T lymphocytes in the tropical splenomegaly syndrome.
Topics: Adolescent; Adult; Antibodies; Chloroquine; Female; Humans; Immunoglobulin G; Immunoglobulin M; Indo | 1984 |
[R.E.M. syndrome or idiopathic reticular erythema].
Topics: Chloroquine; Erythema; Humans; Male; Middle Aged; Syndrome | 1980 |
Protean manifestations of malaria--(multi organ dysfunction syndrome).
Topics: Adult; Antimalarials; Cardiomyopathies; Chloroquine; Diagnosis, Differential; Drug Resistance, Micro | 1996 |
The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein.
Topics: Anemia, Megaloblastic; Animals; Antibodies; Apolipoprotein A-I; Case-Control Studies; Chloroquine; C | 1999 |
Hyperreactive malaria in expatriates returning from sub-Saharan Africa.
Topics: Adolescent; Adult; Africa South of the Sahara; Aged; Animals; Antibodies, Protozoan; Antimalarials; | 2000 |
Brainstem dysfunction: another manifestation of post-malaria neurological syndrome?
Topics: Adult; Antimalarials; Ataxia; Chloroquine; Evoked Potentials, Auditory, Brain Stem; Humans; Malaria, | 2001 |
Dermatomyositis sine myositis and antisynthetase syndrome.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antinuclear; Antirheumatic Agents; Arthri | 2002 |
Extrapyramidal syndrome following chloroquine therapy.
Topics: Basal Ganglia Diseases; Child; Child, Preschool; Chloroquine; Female; Humans; Malaria; Male; Syndrom | 1979 |
[Hypothalamic syndrome as a consequence of years-long use of delagil].
Topics: Adult; Brain Diseases; Chloroquine; Consciousness Disorders; Humans; Hypothalamus; Male; Syndrome; T | 1979 |
[Porphyria erythropoietica congenita Günther and chloroquine (author's transl)].
Topics: Child; Chloroquine; Elasticity; Erythrocytes; Erythropoiesis; Humans; Male; Photosensitivity Disorde | 1978 |
[Therapy of systemic lupus erythematosus and of pseudo-le-syndrome].
Topics: Aged; Azathioprine; Chloroquine; Cyclophosphamide; Diagnosis, Differential; Female; Glucocorticoids; | 1978 |
Ocular sarcoidosis.
Topics: Adrenal Cortex Hormones; Adult; Chloroquine; Conjunctivitis; Eye Diseases; Eye Manifestations; Facia | 1976 |
The hyperreactive malarial splenomegaly syndrome in a European: has the treatment a modulatory effect on the immune system?
Topics: Chloroquine; Humans; Immune System; Malaria; Male; Middle Aged; Splenomegaly; Syndrome | 1990 |
A study on tropical splenomegaly syndrome and chloroquine prophylaxis.
Topics: Adolescent; Adult; Animals; Chloroquine; Female; Humans; India; Malaria; Male; Middle Aged; Plasmodi | 1989 |
Diagnosis of autoerythrocyte sensitization syndrome in the emergency department.
Topics: Adult; Autoimmune Diseases; Chloroquine; Diagnosis, Differential; Emergency Service, Hospital; Eryth | 1989 |
Tropical splenomegaly syndrome and the role of chloroquine prophylaxis.
Topics: Adult; Chloroquine; Female; Humans; Splenomegaly; Syndrome; Tropical Medicine | 1987 |
Lower lip syndrome--a form of lupus erythematosus?
Topics: Adult; Biopsy; Child; Chloroquine; Humans; Lip Diseases; Lupus Erythematosus, Discoid; Neutrophils; | 1973 |
Autoerythrocyte sensitization syndrome.
Topics: Adult; Autoimmune Diseases; Blood Platelets; Chloroquine; Cortisone; Ecchymosis; Erythrocytes; Femal | 1973 |
Visual failure and optic atrophy.
Topics: Adult; Amblyopia; Anemia, Pernicious; Child; Chloroquine; Craniocerebral Trauma; Cyanides; Female; H | 1970 |