Page last updated: 2024-10-24

chloroquine and Stroke

chloroquine has been researched along with Stroke in 3 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
"Chloroquine treatment prevented ganglioside dysregulation 3 days post-stroke and partially prevented complex ganglioside depletion 21 days post-stroke."5.51Chloroquine Restores Ganglioside Homeostasis and Improves Pathological and Behavioral Outcomes Post-stroke in the Rat. ( Caughlin, S; Cechetto, DF; Hepburn, J; Liu, Q; Wang, L; Whitehead, SN; Yeung, KK, 2019)
"Chloroquine pretreatment significantly enhanced rats' short-term spatial memory capacity and attenuated the expression of TLR3, IFR3, and IFN-β in the Hippocampus compared to non-treatment control in tGCI rats."5.39Chloroquine pretreatment inhibits toll-like receptor 3 signaling after stroke. ( Chen, W; Cui, G; Hua, F; Ye, X; Zhao, H; Zhao, Q; Zuo, T, 2013)
"Chloroquine treatment prevented ganglioside dysregulation 3 days post-stroke and partially prevented complex ganglioside depletion 21 days post-stroke."1.51Chloroquine Restores Ganglioside Homeostasis and Improves Pathological and Behavioral Outcomes Post-stroke in the Rat. ( Caughlin, S; Cechetto, DF; Hepburn, J; Liu, Q; Wang, L; Whitehead, SN; Yeung, KK, 2019)
"Chloroquine pretreatment significantly enhanced rats' short-term spatial memory capacity and attenuated the expression of TLR3, IFR3, and IFN-β in the Hippocampus compared to non-treatment control in tGCI rats."1.39Chloroquine pretreatment inhibits toll-like receptor 3 signaling after stroke. ( Chen, W; Cui, G; Hua, F; Ye, X; Zhao, H; Zhao, Q; Zuo, T, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, YY1
Zhang, TY1
Xue, X1
Liu, DM1
Zhang, HT1
Yuan, LL1
Liu, YL1
Yang, HL1
Sun, SB1
Zhang, C1
Xu, HS1
Wu, CF1
Yang, JY1
Caughlin, S1
Hepburn, J1
Liu, Q1
Wang, L1
Yeung, KK1
Cechetto, DF1
Whitehead, SN1
Cui, G1
Ye, X1
Zuo, T1
Zhao, H1
Zhao, Q1
Chen, W1
Hua, F1

Other Studies

3 other studies available for chloroquine and Stroke

ArticleYear
Pseudoginsenoside-F11 attenuates cerebral ischemic injury by alleviating autophagic/lysosomal defects.
    CNS neuroscience & therapeutics, 2017, Volume: 23, Issue:7

    Topics: Animals; Apoptosis; Autophagy; Brain; Brain Edema; Brain Ischemia; Chloroquine; Disease Models, Anim

2017
Chloroquine Restores Ganglioside Homeostasis and Improves Pathological and Behavioral Outcomes Post-stroke in the Rat.
    Molecular neurobiology, 2019, Volume: 56, Issue:5

    Topics: Animals; Behavior, Animal; Cell Survival; Cells, Cultured; Chloroquine; Forelimb; Gangliosides; Home

2019
Chloroquine pretreatment inhibits toll-like receptor 3 signaling after stroke.
    Neuroscience letters, 2013, Aug-26, Volume: 548

    Topics: Animals; Chloroquine; Interferon Regulatory Factor-3; Interferon-beta; Male; Memory; Premedication;

2013