chloroquine has been researched along with Stevens-Johnson Syndrome in 11 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A fatal case of Stevens-Johnson syndrome associated with Fansidar and chloroquine is reported in a 5-year-old boy." | 7.67 | Fatal Stevens-Johnson syndrome associated with Fansidar and chloroquine. ( Bamber, MG; Elder, AT; Gray, JA; Minns, RA, 1986) |
| "A 12-year-old boy developed a phototoxic rash with subsequent progression to Stevens-Johnson syndrome due to prophylactic ingestion of antimalarials (chloroquine and sulfadoxine-pyrimethamine; Fansidar)." | 3.67 | An unusual combination of phototoxicity and Stevens-Johnson syndrome due to antimalarial therapy. ( Hönigsmann, H; Ortel, B; Sivayathorn, A, 1989) |
| "A fatal case of Stevens-Johnson syndrome associated with Fansidar and chloroquine is reported in a 5-year-old boy." | 3.67 | Fatal Stevens-Johnson syndrome associated with Fansidar and chloroquine. ( Bamber, MG; Elder, AT; Gray, JA; Minns, RA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Yadav, V | 1 |
| Sharma, S | 1 |
| Kumar, V | 1 |
| Chawla, A | 1 |
| Logani, A | 1 |
| Cisneros, CG | 1 |
| Romiti, R | 1 |
| Santi, CG | 1 |
| Aoki, V | 1 |
| Valente, NY | 1 |
| Nico, MM | 1 |
| Boffa, MJ | 1 |
| Chalmers, RJ | 1 |
| Kanwar, AJ | 1 |
| Singh, OP | 1 |
| Bazarnaia, NS | 1 |
| Pankova, RA | 1 |
| Iaroshkevich, TF | 1 |
| Volodikhin, VI | 1 |
| Ortel, B | 1 |
| Sivayathorn, A | 1 |
| Hönigsmann, H | 1 |
| Miller, KD | 1 |
| Lobel, HO | 1 |
| Satriale, RF | 1 |
| Kuritsky, JN | 1 |
| Stern, R | 1 |
| Campbell, CC | 1 |
| Phillips-Howard, PA | 1 |
| Warwick Buckler, J | 1 |
| Bamber, MG | 1 |
| Elder, AT | 1 |
| Gray, JA | 1 |
| Minns, RA | 1 |
| Lenox-Smith, I | 1 |
| Shul'tsev, GP | 1 |
| Tsalenchuk, IaP | 1 |
11 other studies available for chloroquine and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Cone Beam Computed Tomographic Cone beam computed tomographic characterization of short root anomaly in chloroquine-induced Stevens-Johnson Syndrome - a case report.
Topics: Adult; Child; Chloroquine; Cone-Beam Computed Tomography; Humans; Male; Stevens-Johnson Syndrome; To | 2022 |
Toxic epidermal necrolysis-like cutaneous lupus erythematosus: A series of three patients.
Topics: Adolescent; Azathioprine; Chloroquine; Diagnosis, Differential; Drug Therapy, Combination; Female; H | 2010 |
Toxic epidermal necrolysis due to chloroquine phosphate.
Topics: Aged; Antimalarials; Chloroquine; Female; Humans; Stevens-Johnson Syndrome | 1994 |
Toxic epidermal necrolysis-drug induced (report of 2 cases).
Topics: Adult; Chloroquine; Humans; Male; Middle Aged; Stevens-Johnson Syndrome; Thioacetazone | 1976 |
[Toxic epidermal necrosis as a manifestation of intolerance to butadione and delagyl].
Topics: Adult; Chloroquine; Female; Humans; Phenylbutazone; Stevens-Johnson Syndrome | 1979 |
An unusual combination of phototoxicity and Stevens-Johnson syndrome due to antimalarial therapy.
Topics: Antimalarials; Child; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Ma | 1989 |
Severe cutaneous reactions among American travelers using pyrimethamine-sulfadoxine (Fansidar) for malaria prophylaxis.
Topics: Adolescent; Adult; Aged; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Eruptions; Eryth | 1986 |
Idiosyncratic reaction resembling toxic epidermal necrolysis caused by chloroquine and maloprim.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Humans; Male; Middle Aged; Pyrimethamine; St | 1988 |
Fatal Stevens-Johnson syndrome associated with Fansidar and chloroquine.
Topics: Child, Preschool; Chloroquine; Drug Combinations; Humans; Malaria; Male; Pyrimethamine; Stevens-John | 1986 |
Fatal Stevens-Johnson syndrome associated with Fansidar and chloroquine.
Topics: Antimalarials; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Pyrimethamine; Ste | 1987 |
[Case of severe allergic reaction of Lyell syndrome type caused by rezokhin in renal amyloidosis].
Topics: Aged; Amyloidosis; Chloroquine; Humans; Kidney Diseases; Male; Stevens-Johnson Syndrome | 1972 |