chloroquine has been researched along with Starvation in 10 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Starvation: Lengthy and continuous deprivation of food. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine (CQ) is a 4-aminoquinoline drug used for the treatment of diverse diseases." | 5.38 | Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy. ( Aryal, S; Cummings, CT; Maycotte, P; Morgan, MJ; Thorburn, A; Thorburn, J, 2012) |
| " However, GGA null flies are hypersensitive to dietary chloroquine and to starvation, implicating GGA in lysosomal function and autophagy." | 3.78 | The unique GGA clathrin adaptor of Drosophila melanogaster is not essential. ( Eissenberg, JC; Ilvarsonn, AM; Luan, S, 2012) |
| " In contrast, depletion of glutathione, induced either by starvation or by pretreatment with buthionine sulfoximine, a potent inhibitor of glutathione synthesis, markedly augmented the fluorescence intensity of OFP in the livers of mice treated with chloroquine." | 3.68 | Relationship between glutathione content and formation of organic solvent-soluble fluorescent pigments in mice treated with chloroquine. ( Nakagawa, K, 1991) |
| "Glioblastomas are highly aggressive tumors that contain treatment resistant stem-like cells." | 1.43 | Targeting Notch Signaling and Autophagy Increases Cytotoxicity in Glioblastoma Neurospheres. ( Chu, Q; Eberhart, CG; Kahlert, UD; Kaur, H; Liu, Y; Maitani, K; Miyahara, H; Natsumeda, M; Zhang, H, 2016) |
| "Chloroquine (CQ) is a 4-aminoquinoline drug used for the treatment of diverse diseases." | 1.38 | Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy. ( Aryal, S; Cummings, CT; Maycotte, P; Morgan, MJ; Thorburn, A; Thorburn, J, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, YJ | 1 |
| Zhang, SS | 1 |
| Guo, XL | 1 |
| Sun, K | 1 |
| Han, ZP | 1 |
| Li, R | 1 |
| Zhao, QD | 1 |
| Deng, WJ | 1 |
| Xie, XQ | 1 |
| Zhang, JW | 1 |
| Wu, MC | 1 |
| Wei, LX | 1 |
| Natsumeda, M | 1 |
| Maitani, K | 1 |
| Liu, Y | 1 |
| Miyahara, H | 1 |
| Kaur, H | 1 |
| Chu, Q | 1 |
| Zhang, H | 1 |
| Kahlert, UD | 1 |
| Eberhart, CG | 1 |
| Maycotte, P | 1 |
| Aryal, S | 1 |
| Cummings, CT | 1 |
| Thorburn, J | 1 |
| Morgan, MJ | 1 |
| Thorburn, A | 1 |
| Luan, S | 1 |
| Ilvarsonn, AM | 1 |
| Eissenberg, JC | 1 |
| Lee, MJ | 1 |
| Fried, SK | 1 |
| Lenk, SE | 1 |
| Susan, PP | 1 |
| Hickson, I | 1 |
| Jasionowski, T | 1 |
| Dunn, WA | 1 |
| Stauber, WT | 1 |
| Bird, JW | 1 |
| Schottelius, BA | 1 |
| Nakagawa, K | 1 |
| Regoeczi, E | 1 |
| Charlwood, PA | 1 |
| Chindemi, PA | 1 |
| Banno, Y | 1 |
| Sasaki, N | 1 |
| Nozawa, Y | 1 |
10 other studies available for chloroquine and Starvation
| Article | Year |
|---|---|
Autophagy contributes to the survival of CD133+ liver cancer stem cells in the hypoxic and nutrient-deprived tumor microenvironment.
Topics: AC133 Antigen; Animals; Antigens, CD; Autophagy; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Chlo | 2013 |
Targeting Notch Signaling and Autophagy Increases Cytotoxicity in Glioblastoma Neurospheres.
Topics: Antimalarials; Autophagy; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chloroquine; Colony-Form | 2016 |
Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy.
Topics: Animals; Antineoplastic Agents; Autophagy; Autophagy-Related Protein 12; Breast Neoplasms; Cell Line | 2012 |
The unique GGA clathrin adaptor of Drosophila melanogaster is not essential.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Autophagy; Chloroquine; Clathrin; Drosophila melanog | 2012 |
Multilevel regulation of leptin storage, turnover, and secretion by feeding and insulin in rat adipose tissue.
Topics: Adipocytes; Adipose Tissue; Animals; Blotting, Northern; Body Weight; Chloroquine; Cycloheximide; In | 2006 |
Ubiquitinated aldolase B accumulates during starvation-induced lysosomal proteolysis.
Topics: Adenine; Amino Acid Sequence; Amino Acids; Animals; Antimalarials; Blood Proteins; Carcinoma, Hepato | 1999 |
Catalase: an enzymatic indicator of the degree of muscle wasting.
Topics: Acid Phosphatase; Animals; Arylsulfatases; Back; Catalase; Cathepsins; Chickens; Chloroquine; Glucur | 1977 |
Relationship between glutathione content and formation of organic solvent-soluble fluorescent pigments in mice treated with chloroquine.
Topics: Acid Phosphatase; Animals; Antimetabolites; Buthionine Sulfoximine; Chloroquine; gamma-Glutamyltrans | 1991 |
The effects of cytotropic compounds on the resialylation of human asialotransferrin type 3 in the rat.
Topics: Alkaloids; Animals; Asialoglycoproteins; Chloroquine; Colchicine; Female; Humans; Leupeptins; Liver; | 1985 |
Secretion heterogeneity of lysosomal enzymes in Tetrahymena pyriformis.
Topics: Acid Phosphatase; Age Factors; alpha-Mannosidase; Ammonium Chloride; Animals; Azides; beta-Galactosi | 1987 |