chloroquine has been researched along with Sicca Syndrome in 22 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine (CQ) was known as an immunomodulatory drug and in the inhibition of autophagy." | 5.51 | The Effect of Chloroquine on the Development of Dry Eye in Sjögren Syndrome Animal Model. ( Cheon, EJ; Chung, SH; Lee, HJ; Shin, S; Yoon, SG, 2019) |
| "Hydroxychloroquine (HCQ) is a lysosomotropic agent that is commonly used for treating Sjögren's disease (SjD)." | 1.91 | Salivary gland LAMP3 mRNA expression is a possible predictive marker in the response to hydroxychloroquine in Sjögren's disease. ( Afione, SA; Atsumi, T; Chiorini, JA; Ji, Y; Motta, ACF; Nakamura, H; Noguchi, M; Oliveira, FR; Rocha, EM; Tanaka, T; Warner, BM; Zheng, C, 2023) |
| "Chloroquine (CQ) was known as an immunomodulatory drug and in the inhibition of autophagy." | 1.51 | The Effect of Chloroquine on the Development of Dry Eye in Sjögren Syndrome Animal Model. ( Cheon, EJ; Chung, SH; Lee, HJ; Shin, S; Yoon, SG, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (45.45) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Nakamura, H | 1 |
| Tanaka, T | 1 |
| Ji, Y | 1 |
| Zheng, C | 1 |
| Afione, SA | 1 |
| Warner, BM | 1 |
| Oliveira, FR | 1 |
| Motta, ACF | 1 |
| Rocha, EM | 1 |
| Noguchi, M | 1 |
| Atsumi, T | 1 |
| Chiorini, JA | 1 |
| Lee, HJ | 1 |
| Shin, S | 1 |
| Yoon, SG | 1 |
| Cheon, EJ | 1 |
| Chung, SH | 1 |
| Dos Reis Neto, ET | 1 |
| Kakehasi, AM | 1 |
| de Medeiros Pinheiro, M | 1 |
| Ferreira, GA | 1 |
| Marques, CDL | 1 |
| da Mota, LMH | 1 |
| Dos Santos Paiva, E | 1 |
| Pileggi, GCS | 1 |
| Sato, EI | 1 |
| Reis, APMG | 1 |
| Xavier, RM | 1 |
| Provenza, JR | 1 |
| Fegan, D | 1 |
| Glennon, MJ | 1 |
| Wu, CH | 1 |
| Li, KJ | 1 |
| Yu, CL | 1 |
| Tsai, CY | 1 |
| Hsieh, SC | 1 |
| Pavsic, N | 1 |
| Mraz, J | 1 |
| Strazar, ZD | 1 |
| Gabrijelcic, J | 1 |
| Toplisek, J | 1 |
| Kozelj, M | 1 |
| Prokselj, K | 1 |
| Kobak, S | 1 |
| Deveci, H | 1 |
| Jin, M | 1 |
| Hwang, SM | 1 |
| Davies, AJ | 1 |
| Shin, Y | 1 |
| Bae, JS | 1 |
| Lee, JH | 1 |
| Lee, EB | 1 |
| Song, YW | 1 |
| Park, K | 1 |
| Müller-Höcker, J | 1 |
| Schmid, H | 1 |
| Weiss, M | 1 |
| Dendorfer, U | 1 |
| Braun, GS | 1 |
| HEATON, JM | 1 |
| Milic, V | 1 |
| Ostojic, P | 1 |
| Brahma, AK | 1 |
| Hay, E | 1 |
| Sturgess, DA | 1 |
| Morgan, LH | 1 |
| Peris, P | 1 |
| Font, J | 1 |
| Grau, JM | 1 |
| Martínez de Osaba, MJ | 1 |
| Filella, X | 1 |
| Muñoz-Gómez, J | 1 |
| Vasil'ev, VI | 1 |
| Simonova, MV | 1 |
| Safonova, TN | 1 |
| Mach, ES | 1 |
| Ivanova, AV | 1 |
| Bezuglov, MF | 1 |
| Dugowson, CE | 1 |
| Gilliland, BC | 1 |
| Coles, RS | 1 |
| Henkind, P | 1 |
| Gold, DH | 1 |
| Cziráki, L | 1 |
| Szemere, P | 1 |
| Missmahl, HP | 1 |
| Deseö, E | 1 |
| Chlebowski, J | 1 |
| Propkopczuk, J | 1 |
5 reviews available for chloroquine and Sicca Syndrome
| Article | Year |
|---|---|
Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases.
Topics: Antimalarials; Antiphospholipid Syndrome; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; | 2020 |
Management of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyc | 1986 |
Ocular manifestations of connective tissue disease.
Topics: Adrenal Cortex Hormones; Child; Chloroquine; Connective Tissue Diseases; Eye Diseases; Female; Giant | 1985 |
Ocular manifestations of rheumatic disorders. Natural and iatrogenic.
Topics: Adrenal Cortex Hormones; Arteritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Chloroquine; Conjunc | 1973 |
[Amyloidosis in chronic rheumatic diseases].
Topics: Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Biopsy; Chloroquine; Chronic Disease; Collagen Dise | 1968 |
1 trial available for chloroquine and Sicca Syndrome
| Article | Year |
|---|---|
[Comparative evaluation of the treatment of Sjögren's syndrome with anti-rheumatic preparations].
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Chlorambucil; Chloroquine; Clinical Trials as Topic; Dr | 1988 |
16 other studies available for chloroquine and Sicca Syndrome
| Article | Year |
|---|---|
Salivary gland LAMP3 mRNA expression is a possible predictive marker in the response to hydroxychloroquine in Sjögren's disease.
Topics: Animals; Chloroquine; Hydroxychloroquine; Lysosomal Membrane Proteins; Mice; Retrospective Studies; | 2023 |
The Effect of Chloroquine on the Development of Dry Eye in Sjögren Syndrome Animal Model.
Topics: Animals; Antirheumatic Agents; Autophagy; Autophagy-Related Protein 5; Biomarkers; Chloroquine; Corn | 2019 |
SLE and dental erosion: a lethal cocktail.
Topics: Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Chloroquine; Female; Fever; Fruit; Human | 2014 |
Sjögren's Syndrome Antigen B Acts as an Endogenous Danger Molecule to Induce Interleukin-8 Gene Expression in Polymorphonuclear Neutrophils.
Topics: Ammonium Chloride; Autoantigens; Chloroquine; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; HL- | 2015 |
Shunt reversal due to deterioration of chloroquine-induced cardiomyopathy in a patient with primary Sjögren syndrome.
Topics: Aged; Antimalarials; Cardiac Catheterization; Cardiomyopathies; Chloroquine; Female; Follow-Up Studi | 2016 |
Retinopathy due to antimalarial drugs in patients with connective tissue diseases: are they so innocent? A single center retrospective study.
Topics: Adolescent; Adult; Aged; Antimalarials; Arthritis, Rheumatoid; Chi-Square Distribution; Chloroquine; | 2010 |
Autoantibodies in primary Sjögren's syndrome patients induce internalization of muscarinic type 3 receptors.
Topics: Adult; Aged; Autoantibodies; Calcium; Carbachol; Chloroquine; Clathrin; Down-Regulation; Female; Flu | 2012 |
Chloroquine-induced phospholipidosis of the kidney mimicking Fabry's disease: case report and review of the literature.
Topics: alpha-Galactosidase; Chloroquine; Diagnosis, Differential; Fabry Disease; Female; Humans; Hypertensi | 2003 |
Antimalarials in treatment of Sjogren's syndrome.
Topics: Antimalarials; Blood Group Antigens; Chloroquine; Sjogren's Syndrome | 1959 |
Cerebellar ataxia in a patient with primary Sjögren's syndrome after treatment with chloroquine.
Topics: Aged; Antirheumatic Agents; Cerebellar Ataxia; Chloroquine; Female; Humans; Sjogren's Syndrome | 2008 |
Acquired Brown's syndrome and primary Sjogren's syndrome.
Topics: Adult; Chloroquine; Diplopia; Female; Humans; Ophthalmoplegia; Prednisolone; Sjogren's Syndrome | 1995 |
Calcitriol-mediated hypercalcaemia and increased interleukins in a patient with sarcoid myopathy.
Topics: Antirheumatic Agents; Calcitonin; Calcitriol; Chloroquine; Clodronic Acid; Female; Humans; Hypercalc | 1999 |
[Comparative evaluation of various methods of treatment of patients with Sjögren's disease and syndrome at the hospital-polyclinic stages].
Topics: Ambulatory Care; Chloroquine; Dose-Response Relationship, Drug; Hospitalization; Humans; Prednisolon | 1988 |
[Successful combined immunosuppressive and corticosteroid therapy of Sjögren's disease].
Topics: Adult; Azathioprine; Chloroquine; Female; Humans; Male; Middle Aged; Prednisolone; Sjogren's Syndrom | 1974 |
Treatment of Sjögren's syndrome by delagil.
Topics: Adult; Chloroquine; Female; Humans; Middle Aged; Phosphates; Sjogren's Syndrome | 1968 |
[Trial of Sjögren's syndrome treatment with arechin (Resochin)].
Topics: Chloroquine; Female; Humans; Middle Aged; Sjogren's Syndrome | 1966 |