chloroquine has been researched along with Sarcoidosis, Pulmonary in 6 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Sarcoidosis, Pulmonary: Sarcoidosis affecting predominantly the lungs, the site most frequently involved and most commonly causing morbidity and mortality in sarcoidosis. Pulmonary sarcoidosis is characterized by sharply circumscribed granulomas in the alveolar, bronchial, and vascular walls, composed of tightly packed cells derived from the mononuclear phagocyte system. The clinical symptoms when present are dyspnea upon exertion, nonproductive cough, and wheezing. (Cecil Textbook of Medicine, 19th ed, p431)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bullous pemphigoid has been reported to be induced or precipitated by systemic therapy with several drugs, including penicillamine, captopril, frusemide and ampicillin." | 5.30 | Bullous pemphigoid developing during systemic therapy with chloroquine. ( Barker, JN; Black, MM; Millard, TP; Smith, HR, 1999) |
| "Bullous pemphigoid has been reported to be induced or precipitated by systemic therapy with several drugs, including penicillamine, captopril, frusemide and ampicillin." | 1.30 | Bullous pemphigoid developing during systemic therapy with chloroquine. ( Barker, JN; Black, MM; Millard, TP; Smith, HR, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Polverosi, R | 1 |
| Russo, R | 1 |
| Coran, A | 1 |
| Battista, A | 1 |
| Agostini, C | 1 |
| Pomerri, F | 1 |
| Giraudo, C | 1 |
| Paramothayan, S | 2 |
| Lasserson, T | 1 |
| Walters, EH | 2 |
| Gol'dshteĭn, VD | 1 |
| Ivantsova, LN | 1 |
| Lasserson, TJ | 1 |
| Baltzan, M | 1 |
| Mehta, S | 1 |
| Kirkham, TH | 1 |
| Cosio, MG | 1 |
| Millard, TP | 1 |
| Smith, HR | 1 |
| Black, MM | 1 |
| Barker, JN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Controlled Trial Testing the Effect of Hydroxychloroquine Combined With Low-dose Corticosteroid Therapy in Pulmonary Sarcoidosis[NCT05247554] | Phase 3 | 200 participants (Anticipated) | Interventional | 2022-03-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for chloroquine and Sarcoidosis, Pulmonary
| Article | Year |
|---|---|
Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis.
Topics: Antineoplastic Agents; Chloroquine; Cyclosporine; Humans; Immunosuppressive Agents; Methotrexate; Ra | 2003 |
Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis.
Topics: Antineoplastic Agents; Chloroquine; Cyclosporine; Humans; Immunosuppressive Agents; Methotrexate; Pe | 2006 |
1 trial available for chloroquine and Sarcoidosis, Pulmonary
| Article | Year |
|---|---|
Randomized trial of prolonged chloroquine therapy in advanced pulmonary sarcoidosis.
Topics: Adult; Antirheumatic Agents; Biopsy; Chloroquine; Diagnostic Imaging; Dose-Response Relationship, Dr | 1999 |
3 other studies available for chloroquine and Sarcoidosis, Pulmonary
| Article | Year |
|---|---|
Typical and atypical pattern of pulmonary sarcoidosis at high-resolution CT: relation to clinical evolution and therapeutic procedures.
Topics: Adult; Aged; Antirheumatic Agents; Chloroquine; Female; Humans; Male; Methotrexate; Middle Aged; Ret | 2014 |
[Long-term results of treatment and prediction in patients with sarcoidosis].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chloroquine; Female; Follow-Up Studies; Humans; Hydr | 2006 |
Bullous pemphigoid developing during systemic therapy with chloroquine.
Topics: Antirheumatic Agents; Biopsy; Chloroquine; Drug Eruptions; Dyspnea; Erythema Multiforme; Fluorescent | 1999 |