chloroquine has been researched along with Rhabdomyolysis in 5 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 36-year-old woman with systemic lupus erythematosus was admitted to our hospital with malaise, myalgia, dysphagia, fever, preserved muscle strength, leukocytosis (15,600 cells), and increased creatine kinase of 1,358 IU/L that reached 75,000 IU/L in few days." | 1.37 | Fatal rhabdomyolysis in systemic lupus erythematosus. ( Bonfa, E; da Mota, LM; de Carvalho, JF, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamel, Y | 1 |
| Mauvais, FX | 1 |
| Madrange, M | 1 |
| Renard, P | 1 |
| Lebreton, C | 1 |
| Nemazanyy, I | 1 |
| Pellé, O | 1 |
| Goudin, N | 1 |
| Tang, X | 1 |
| Rodero, MP | 1 |
| Tuchmann-Durand, C | 1 |
| Nusbaum, P | 1 |
| Brindley, DN | 1 |
| van Endert, P | 1 |
| de Lonlay, P | 1 |
| de Carvalho, JF | 1 |
| da Mota, LM | 1 |
| Bonfa, E | 1 |
| Mishra, SK | 1 |
| Satpathy, SK | 1 |
| Satpathy, R | 1 |
| Nanda, NC | 1 |
| Berlit, P | 1 |
| Härle, M | 1 |
| Buss, J | 1 |
| Klötzsch, C | 1 |
| Poels, PJ | 1 |
| Dolmans, WM | 1 |
| Gabreëls, FJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acute Rhabdomyolysis and Muscle Pain Associated With Mutations in the LPIN1 Gene - A Retrospective Study Describing the Safety and Efficacy of Hydroxychloroquine Sulfate Given on a Compassionate Basis to Patients Suffering From Lipin-1 Deficiency[NCT04007562] | 0 participants (Actual) | Observational | 2019-07-31 | Withdrawn (stopped due to The study never started) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for chloroquine and Rhabdomyolysis
| Article | Year |
|---|---|
Compromised mitochondrial quality control triggers lipin1-related rhabdomyolysis.
Topics: Autophagosomes; Child; Child, Preschool; Chloroquine; DNA, Mitochondrial; Endosomes; Female; Follow- | 2021 |
Fatal rhabdomyolysis in systemic lupus erythematosus.
Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Antibodies, Antinuclear; Arthritis; Azathioprine; | 2011 |
Myoglobinuric renal failure following rhabdomyolysis.
Topics: Acute Kidney Injury; Back Injuries; Child; Chloroquine; Female; Humans; Male; Middle Aged; Myoglobin | 1994 |
Rhabdomyolysis in vasculitis.
Topics: Adult; Chloroquine; Connective Tissue Diseases; Fatal Outcome; Female; Humans; Prednisolone; Rhabdom | 1993 |
Rhabdomyolysis associated with malaria tertiana in a patient with myoadenylate deaminase deficiency.
Topics: Acute Kidney Injury; Adult; AMP Deaminase; Chloroquine; Humans; Malaria, Vivax; Male; Rhabdomyolysis | 1993 |