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chloroquine and Pulmonary Arterial Hypertension

chloroquine has been researched along with Pulmonary Arterial Hypertension in 1 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Pulmonary Arterial Hypertension: A progressive rare pulmonary disease characterized by high blood pressure in the PULMONARY ARTERY.

Research Excerpts

ExcerptRelevanceReference
"Chloroquine (CLQ) has been observed to inhibit calcium influx."5.62The effect of chloroquine on the TRPC1, TRPC6, and CaSR in the pulmonary artery smooth muscle cells in hypoxia-induced experimental pulmonary artery hypertension. ( Akin, AT; Başaran, KE; Kaymak, E; Özdamar, S; Taheri, S; Tufan, E; Yakan, B, 2021)
"Chloroquine (CLQ) has been observed to inhibit calcium influx."1.62The effect of chloroquine on the TRPC1, TRPC6, and CaSR in the pulmonary artery smooth muscle cells in hypoxia-induced experimental pulmonary artery hypertension. ( Akin, AT; Başaran, KE; Kaymak, E; Özdamar, S; Taheri, S; Tufan, E; Yakan, B, 2021)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Kaymak, E1
Akin, AT1
Tufan, E1
Başaran, KE1
Taheri, S1
Özdamar, S1
Yakan, B1

Other Studies

1 other study available for chloroquine and Pulmonary Arterial Hypertension

ArticleYear
The effect of chloroquine on the TRPC1, TRPC6, and CaSR in the pulmonary artery smooth muscle cells in hypoxia-induced experimental pulmonary artery hypertension.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:2

    Topics: Animals; Arterioles; Body Weight; Cell Line; Chloroquine; Disease Models, Animal; Hypoxia; Lung; Mal

2021