chloroquine has been researched along with Protein Aggregation, Pathological in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Protein Aggregation, Pathological: A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lan, JS | 1 |
| Xie, SS | 1 |
| Li, SY | 1 |
| Pan, LF | 1 |
| Wang, XB | 1 |
| Kong, LY | 1 |
| Pierzynowska, K | 1 |
| Gaffke, L | 1 |
| Hać, A | 1 |
| Mantej, J | 1 |
| Niedziałek, N | 1 |
| Brokowska, J | 1 |
| Węgrzyn, G | 1 |
2 other studies available for chloroquine and Protein Aggregation, Pathological
| Article | Year |
|---|---|
Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain B | 2014 |
Correction of Huntington's Disease Phenotype by Genistein-Induced Autophagy in the Cellular Model.
Topics: Autophagy; Chloroquine; Drug Evaluation, Preclinical; Genes, Reporter; Genistein; HEK293 Cells; Huma | 2018 |