chloroquine has been researched along with Porphyrias in 116 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Longer remissions after the phlebotomy therapy than after the low-dose chloroquine treatment were ascertained by means of the long-term follow-up of a large group of porphyria cutanea tarda patients." | 9.05 | A comparative study of the results of phlebotomy therapy and low-dose chloroquine treatment in porphyria cutanea tarda. ( Chlumský, J; Malina, L, 1981) |
| "We report a 33-year-old female patient who had hemodialysis-associated pseudoporphyria which did not respond to treatment with oral N-acetylcysteine." | 7.77 | Hemodialysis-associated pseudoporphyria resistant to N-acetylcysteine. ( Alouane, Z; Bahadi, A; El Kabbaj, D; Laalou, A; Oualim, Z, 2011) |
| "In 59 patients showing clear clinical and biochemical signs of porphyria cutanea tarda (PCT), we tested 3 different modes of therapy: 20 patients received combined treatment with repeated bleeding and chloroquine, 24 patients were exclusively treated with oral chloroquine in low doses, and 15 patients underwent repeated phlebotomy only." | 7.68 | [Results of treatment of porphyria cutanea tarda with bloodletting and chloroquine]. ( Batlle, A; Guzman, H; Seubert, A; Seubert, S; Stella, AM, 1990) |
| "The knowledge about the influence of chloroquine phosphate (CQ) on the iron metabolism in porphyria cutanea tarda (PCT) is still insufficient." | 7.68 | [Iron metabolism and chloroquine phosphate therapy in porphyria cutanea tarda]. ( Köstler, E; Pollack, P; Riedel, H; Seebacher, C, 1990) |
| "Seven patients with porphyria cutanea tarda received a total of ten courses of low-dose oral chloroquine therapy (125 mg chloroquine phosphate twice weekly)." | 7.67 | Low-dose oral chloroquine in the treatment of porphyria cutanea tarda. ( Ashton, RE; Hawk, JL; Magnus, IA, 1984) |
| "Forty-six patients with porphyria cutanea tarda were observed for a mean period of 32 months (range 4-86) after treatment with high-dose, short-course chloroquine phosphate." | 7.67 | Long-term effect of high-dose, short-course chloroquine therapy on porphyria cutanea tarda. ( Tsega, E, 1987) |
| "Treatment of a six-year-old boy with porphyria congenita (Günther) by small amounts of chloroquine was followed by a sharp but transient increase of the urinary excretion of porphyrins." | 7.66 | [Porphyria erythropoietica congenita Günther and chloroquine (author's transl)]. ( Ippen, H; Seubert, A; Seubert, S; Tillmann, W, 1978) |
| "Treatment of a patient with porphyria cutanea tarda with low dose chloroquine improved the clinical and biochemical abnormalities in association with a reduction in photosensitivity as shown by changes in the action spectrum." | 7.66 | Photosensitivity after treatment of porphyria cutanea tarda with low dose chloroquine. ( Gould, P, 1978) |
| "The treatment of Porphyria Cutaneous Tarda (PCT) has greatly improved by the introduction of low-dose chloroquine." | 7.66 | [Effect of chloroquine in porphyria cutanea tarda]. ( Herrero, C; Muniesa, A, 1980) |
| "In thirty-four patients with porphyria cutanea tarda treated with small doses of chloroquine, liver biopsies were performed before and after treatment." | 7.66 | Liver changes in porphyria cutanea tarda patients treated with chloroquine. ( Chlumska, A; Chlumsky, J; Malina, L, 1980) |
| "Intermittent chloroquine medication was given to 15 patients with porphyria cutanea tarda." | 7.66 | [Treatment of porphyria cutanea tarda with intermittent chloroquine]. ( Formanek, I; Raff, M, 1980) |
| "Treatment of porphyria cutanea tarda (PCT) with chloroquine risks serious side-effects so we have combined it with phlebotomy." | 7.65 | Treatment of porphyria cutanea tarda with chloroquine and phlebotomy. ( Swanbeck, G; Wennersten, G, 1977) |
| "She was being treated for porphyria cutanea tarda (p." | 5.27 | [Death following administration of 1,250 mg chloroquine in porphyria cutanea tarda]. ( Drasch, G; Eisenmenger, W, 1986) |
| " After treatment with Resochin in an erroneously high dosage (1." | 5.26 | [Accident in treatment of porphyria cutanea tarda by chloroquine (Resochin) (author's transl)]. ( Eichenauer, MG; Goerz, G; Krieg, T, 1976) |
| "Longer remissions after the phlebotomy therapy than after the low-dose chloroquine treatment were ascertained by means of the long-term follow-up of a large group of porphyria cutanea tarda patients." | 5.05 | A comparative study of the results of phlebotomy therapy and low-dose chloroquine treatment in porphyria cutanea tarda. ( Chlumský, J; Malina, L, 1981) |
| " Porphyria cutanea tarda can be effectively treated by phlebotomy or low dose chloroquine." | 4.81 | Management of acute and cutaneous porphyrias. ( Badminton, MN; Elder, GH, 2002) |
| "We report a 33-year-old female patient who had hemodialysis-associated pseudoporphyria which did not respond to treatment with oral N-acetylcysteine." | 3.77 | Hemodialysis-associated pseudoporphyria resistant to N-acetylcysteine. ( Alouane, Z; Bahadi, A; El Kabbaj, D; Laalou, A; Oualim, Z, 2011) |
| "Five patients with porphyria cutanea tarda (PCT) were treated with a prolonged, low-dose chloroquine regimen (250 mg twice weekly)." | 3.68 | Skin morphology in porphyria cutanea tarda does not improve despite clinical remission. ( Mustajoki, P; Niemi, KM; Timonen, K, 1991) |
| "The knowledge about the influence of chloroquine phosphate (CQ) on the iron metabolism in porphyria cutanea tarda (PCT) is still insufficient." | 3.68 | [Iron metabolism and chloroquine phosphate therapy in porphyria cutanea tarda]. ( Köstler, E; Pollack, P; Riedel, H; Seebacher, C, 1990) |
| "In 59 patients showing clear clinical and biochemical signs of porphyria cutanea tarda (PCT), we tested 3 different modes of therapy: 20 patients received combined treatment with repeated bleeding and chloroquine, 24 patients were exclusively treated with oral chloroquine in low doses, and 15 patients underwent repeated phlebotomy only." | 3.68 | [Results of treatment of porphyria cutanea tarda with bloodletting and chloroquine]. ( Batlle, A; Guzman, H; Seubert, A; Seubert, S; Stella, AM, 1990) |
| "A 56-year-old patient suffering from porphyria cutanea tarda (PCT) was sufficiently treated with chloroquine and occasional bleeding." | 3.68 | [Artefacts in porphyria cutanea tarda]. ( Egger, B; Goerz, G, 1990) |
| "Seven patients with porphyria cutanea tarda received a total of ten courses of low-dose oral chloroquine therapy (125 mg chloroquine phosphate twice weekly)." | 3.67 | Low-dose oral chloroquine in the treatment of porphyria cutanea tarda. ( Ashton, RE; Hawk, JL; Magnus, IA, 1984) |
| "Seventy-three patients with porphyria cutanea tarda (PCT) were treated with chloroquine phosphate, which was administered in doses of 250 mg twice a week for more than 1 year on average." | 3.67 | [Therapeutic and pathogenetic aspects of porphyria cutanea tarda]. ( Kemmer, C; Köstler, E; Riedel, H; Seebacher, C, 1986) |
| "Forty-six patients with porphyria cutanea tarda were observed for a mean period of 32 months (range 4-86) after treatment with high-dose, short-course chloroquine phosphate." | 3.67 | Long-term effect of high-dose, short-course chloroquine therapy on porphyria cutanea tarda. ( Tsega, E, 1987) |
| "Rats were treated with the well-known porphyrogen hexachlorobenzene (HCB) to induce experimental porphyria." | 3.67 | Influence of chloroquine on the porphyrin metabolism. ( Bolsen, K; Goerz, G; Merk, H, 1985) |
| "A female patient with porphyria cutanea tarda (PCT) clinically cured by a low-dose chloroquine treatment showed neither exacerbation of the disease nor an increased excretion of urinary porphyrins during pregnancy." | 3.66 | Porphyria cutanea tarda and pregnancy. ( Goerz, G; Hammer, G, 1983) |
| "The treatment of Porphyria Cutaneous Tarda (PCT) has greatly improved by the introduction of low-dose chloroquine." | 3.66 | [Effect of chloroquine in porphyria cutanea tarda]. ( Herrero, C; Muniesa, A, 1980) |
| "Treatment of a six-year-old boy with porphyria congenita (Günther) by small amounts of chloroquine was followed by a sharp but transient increase of the urinary excretion of porphyrins." | 3.66 | [Porphyria erythropoietica congenita Günther and chloroquine (author's transl)]. ( Ippen, H; Seubert, A; Seubert, S; Tillmann, W, 1978) |
| "Treatment of a patient with porphyria cutanea tarda with low dose chloroquine improved the clinical and biochemical abnormalities in association with a reduction in photosensitivity as shown by changes in the action spectrum." | 3.66 | Photosensitivity after treatment of porphyria cutanea tarda with low dose chloroquine. ( Gould, P, 1978) |
| " The treatment of porphyria cutanea tarda with chloroquine shows good success." | 3.66 | [Modern internal therapy of skin diseases (author's transl)]. ( Goerz, G, 1979) |
| "Intermittent chloroquine medication was given to 15 patients with porphyria cutanea tarda." | 3.66 | [Treatment of porphyria cutanea tarda with intermittent chloroquine]. ( Formanek, I; Raff, M, 1980) |
| "In thirty-four patients with porphyria cutanea tarda treated with small doses of chloroquine, liver biopsies were performed before and after treatment." | 3.66 | Liver changes in porphyria cutanea tarda patients treated with chloroquine. ( Chlumska, A; Chlumsky, J; Malina, L, 1980) |
| "The effect of ethanol, phenobarbitone, griseofulvin or chloroquine on 3,4-diethoxycarbonyl-1,4-dihydrocollidine (DDC)-induced porphyria in rats has been studied in experiments lasting up to 40 days." | 3.65 | Study of the effects of certain drugs on experimental porphyria in rats. ( Bhutani, LK; Bikhchandani, R; Deshpande, SG; Kandhari, KC; Narang, BS, 1977) |
| "Treatment of porphyria cutanea tarda (PCT) with chloroquine risks serious side-effects so we have combined it with phlebotomy." | 3.65 | Treatment of porphyria cutanea tarda with chloroquine and phlebotomy. ( Swanbeck, G; Wennersten, G, 1977) |
| "The porphyrias are caused by hereditary defects in the synthesis of heme." | 1.27 | The porphyrias. ( Rosen, T; Sekula, SA; Tschen, JA, 1986) |
| "She was being treated for porphyria cutanea tarda (p." | 1.27 | [Death following administration of 1,250 mg chloroquine in porphyria cutanea tarda]. ( Drasch, G; Eisenmenger, W, 1986) |
| " After treatment with Resochin in an erroneously high dosage (1." | 1.26 | [Accident in treatment of porphyria cutanea tarda by chloroquine (Resochin) (author's transl)]. ( Eichenauer, MG; Goerz, G; Krieg, T, 1976) |
| "Diabetes mellitus was found in 15%; systemic lupus erythematosus in 5%; elevated serum iron level in 62%; and, abnormal liver function test results in 60%." | 1.26 | Porphyria cutanea tarda. Clinical features and laboratory findings in 40 patients. ( Bickers, DR; Deleo, VA; Grossman, ME; Harber, LC; Poh-Fitzpatrick, MB, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 108 (93.10) | 18.7374 |
| 1990's | 6 (5.17) | 18.2507 |
| 2000's | 1 (0.86) | 29.6817 |
| 2010's | 1 (0.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El Kabbaj, D | 1 |
| Laalou, A | 1 |
| Alouane, Z | 1 |
| Bahadi, A | 1 |
| Oualim, Z | 1 |
| LINDEN, IH | 1 |
| STEFFEN, CG | 1 |
| NEWCOMER, VD | 1 |
| CHAPMAN, M | 1 |
| DAVIS, MJ | 1 |
| PLOEG, DE | 1 |
| LONDON, ID | 1 |
| MARSDEN, CW | 1 |
| GROGG, E | 1 |
| MACAULAY, WL | 1 |
| EMBREE, PW | 1 |
| BELUKHA, UK | 1 |
| RIMINGTON, C | 1 |
| HAMAGUCHI, T | 1 |
| KOTANI, Y | 1 |
| ISHIBUCHI, M | 1 |
| ZIEKUR, U | 1 |
| SWEENEY, GD | 3 |
| SAUNDERS, SJ | 1 |
| DOWDLE, EB | 1 |
| EALES, L | 1 |
| Riedel, H | 4 |
| Justus, J | 1 |
| Köstler, E | 5 |
| Pätzold, K | 2 |
| Kemmer, C | 2 |
| Cramers, M | 1 |
| Jepsen, LV | 1 |
| Malina, L | 6 |
| Chlumský, J | 4 |
| Goerz, G | 12 |
| Strohmeyer, G | 1 |
| Ashton, RE | 1 |
| Hawk, JL | 1 |
| Magnus, IA | 1 |
| Bidrat, MS | 1 |
| Montag, H | 1 |
| Schmeel, A | 1 |
| Seebacher, C | 3 |
| Bässler, E | 1 |
| Stölzel, U | 1 |
| Michel, B | 1 |
| Guillot, B | 1 |
| Guilhou, JJ | 1 |
| Meynadier, J | 1 |
| Chinarro, S | 1 |
| de Salamanca, RE | 1 |
| Perpiñá, J | 1 |
| Muñoz, JJ | 1 |
| Peña, ML | 1 |
| Idel'son, LI | 1 |
| Hammer, G | 1 |
| Wennersten, G | 2 |
| Ros, AM | 1 |
| Tanenbaum, L | 1 |
| Tuffanelli, DL | 1 |
| Herrero, C | 1 |
| Muniesa, A | 1 |
| Krivosheev, BN | 1 |
| Martásek, P | 3 |
| Jirsa, M | 5 |
| Kordac, V | 10 |
| Tsega, E | 3 |
| Damtew, B | 2 |
| Landells, JW | 2 |
| Besrat, A | 2 |
| Seyoum, E | 2 |
| Holvay, E | 2 |
| Anderson, PC | 2 |
| Kaláb, M | 4 |
| Semrádová, M | 4 |
| Papezová, R | 2 |
| Soldátová, H | 3 |
| Błaszczyk, M | 1 |
| Daoud, S | 1 |
| Chorzelski, T | 1 |
| Jabłońska, S | 1 |
| Sulej, J | 1 |
| Chlumska, A | 2 |
| Vizethum, W | 1 |
| Bolsen, K | 3 |
| Simon, K | 1 |
| Weber, K | 1 |
| Horkay, I | 2 |
| Nagy, E | 2 |
| Gerwel, M | 1 |
| Raff, M | 1 |
| Formanek, I | 1 |
| Badminton, MN | 1 |
| Elder, GH | 1 |
| Krieg, T | 2 |
| Finnerty, EF | 1 |
| Muhlbauer, JE | 1 |
| Pathak, MA | 1 |
| Jones, KG | 1 |
| Grossman, ME | 1 |
| Bickers, DR | 1 |
| Poh-Fitzpatrick, MB | 1 |
| Deleo, VA | 1 |
| Harber, LC | 1 |
| Dobiás, J | 1 |
| Gould, P | 1 |
| Ippen, H | 1 |
| Tillmann, W | 1 |
| Seubert, S | 2 |
| Seubert, A | 2 |
| Fromke, VL | 1 |
| Bossenmaier, I | 1 |
| Cardinal, R | 1 |
| Watson, CJ | 1 |
| Mathews-Roth, MM | 1 |
| Sams, WM | 1 |
| Roller, JA | 1 |
| Deshpande, SG | 1 |
| Kandhari, KC | 1 |
| Narang, BS | 1 |
| Bikhchandani, R | 1 |
| Bhutani, LK | 1 |
| Marecek, Z | 2 |
| Hunter, GA | 3 |
| Donald, GF | 3 |
| Swanbeck, G | 1 |
| Thornsvard, CT | 1 |
| Guider, BA | 1 |
| Kimball, DB | 1 |
| Jaschke, E | 1 |
| Kowertz, MJ | 2 |
| Eichenauer, MG | 1 |
| Adjarov, D | 1 |
| Kerimova, M | 1 |
| Timonen, K | 1 |
| Niemi, KM | 1 |
| Mustajoki, P | 1 |
| Pollack, P | 1 |
| Ginsburg, AD | 1 |
| Margesson, LJ | 1 |
| Feleki, K | 1 |
| Stella, AM | 2 |
| Guzman, H | 1 |
| Batlle, A | 1 |
| Egger, B | 1 |
| Heinicke, HJ | 1 |
| Schneider, F | 1 |
| Hensel, J | 1 |
| Kotal, P | 2 |
| Doss, MO | 1 |
| Enríquez de Salamanca, R | 1 |
| Cervinka, J | 1 |
| Papezová, P | 1 |
| Sekula, SA | 1 |
| Tschen, JA | 1 |
| Rosen, T | 1 |
| Battle, AM | 1 |
| De Kaminsky, AR | 1 |
| Kaminsky, C | 1 |
| Mariano, HG | 1 |
| Drasch, G | 1 |
| Eisenmenger, W | 1 |
| Seuwen, P | 1 |
| Schmitter, H | 1 |
| Merk, H | 2 |
| Lissner, R | 1 |
| Goh, CL | 1 |
| Zoubek, V | 1 |
| Handa, F | 1 |
| Walia, RL | 1 |
| Sadana, JK | 1 |
| Gill, BS | 1 |
| Tamayo, L | 1 |
| Ruiz-Maldonado, R | 1 |
| Ridaura, C | 1 |
| Meurer, M | 1 |
| Schulte, C | 1 |
| Weiler, A | 1 |
| Reed, WB | 1 |
| Howard, HF | 1 |
| Knutsson, F | 1 |
| Lindstedt, G | 1 |
| Norrby, A | 1 |
| Rödjer, S | 1 |
| Taljaard, JJ | 2 |
| Shanley, BC | 2 |
| Joubert, SM | 2 |
| Deppe, WM | 2 |
| Scholnick, PL | 1 |
| Epstein, J | 1 |
| Marver, HS | 1 |
| Copeman, PW | 1 |
| Beritić, T | 1 |
| Prpić-Majić, D | 1 |
| Roman, W | 1 |
| Taylor, AE | 1 |
| Stewart-Wynne, EG | 1 |
| Snitker, G | 1 |
| Hoo, TT | 1 |
| Vogler, WR | 1 |
| Galambos, JT | 1 |
| Olansky, S | 1 |
| Saltzer, EI | 1 |
| Redeker, AG | 2 |
| Wilson, JW | 1 |
| Bloom, M | 1 |
| Felsher, BF | 1 |
10 reviews available for chloroquine and Porphyrias
| Article | Year |
|---|---|
Antimalarial agents. Chloroquine, hydroxychloroquine, and quinacrine.
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents; Chloroquine; DNA; Eye Diseases; Female; Hemat | 1980 |
Management of acute and cutaneous porphyrias.
Topics: Arginine; beta Carotene; Chloroquine; Estrogens; Ethanol; Heme; Humans; Phlebotomy; Porphyria Cutane | 2002 |
Porphyria cutanea tarda.
Topics: Adolescent; Aged; Alcoholism; Animals; Chick Embryo; Child; Chloroquine; Diagnosis, Differential; He | 1979 |
Therapy of human photosensitivity.
Topics: Administration, Oral; Administration, Topical; Adult; Aminobenzoates; Benzophenones; Carotenoids; Ch | 1975 |
Chloroquine: its therapeutic use in photosensitive eruptions.
Topics: Antimalarials; Child, Preschool; Chloroquine; Female; Fetal Diseases; Humans; Lupus Erythematosus, D | 1976 |
[Porphyria cutanea tarda (chronic hepatic porphyria): new aspects on pathogenesis, diagnosis and therapy with a review of the workshop, "Cutaneous porphyrias" at the 17th World Congress of Dermatology in Berlin 1987].
Topics: Chloroquine; Humans; Liver Diseases; Porphyrias; Skin Diseases | 1988 |
[Porphyria hepatocutaneous tarda. Etiopathogenesis and physiopathologic treatment].
Topics: Chloroquine; Humans; Liver Diseases; Plasma Exchange; Porphyrias; Porphyrins; Skin Diseases | 1987 |
Porphyria cutanea tarda, or the uroporphyrinogen decarboxylase deficiency diseases.
Topics: Animals; Bloodletting; Carboxy-Lyases; Chloroquine; Chromatography, High Pressure Liquid; Disease Mo | 1986 |
Chloroquine.
Topics: Abnormalities, Drug-Induced; Animals; Ascorbic Acid; Child; Chloroquine; Enzymes; Eye Diseases; Fema | 1967 |
[Porphyrias].
Topics: Acute Disease; Adenine Nucleotides; Chelating Agents; Chloroquine; Cholestyramine Resin; Chronic Dis | 1969 |
3 trials available for chloroquine and Porphyrias
| Article | Year |
|---|---|
A comparative study of the results of phlebotomy therapy and low-dose chloroquine treatment in porphyria cutanea tarda.
Topics: Adult; Aged; Bloodletting; Chloroquine; Female; Humans; Liver; Male; Middle Aged; Porphyrias; Recurr | 1981 |
[Comparative evaluation of the therapeutic effectiveness of small and regular doses of delagil in porphyria cutanea tarda].
Topics: Adult; Aged; Chloroquine; Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Male; Middle | 1981 |
[Antimalarials in the treatment of porphyria cutanea tarda].
Topics: Adult; Chloroquine; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Long-Term Care; Male; | 1973 |
103 other studies available for chloroquine and Porphyrias
| Article | Year |
|---|---|
Hemodialysis-associated pseudoporphyria resistant to N-acetylcysteine.
Topics: Acetylcysteine; Administration, Oral; Adult; Chloroquine; Drug Resistance; Female; Humans; Kidney Fa | 2011 |
Development of porphyria during chloroquine therapy for chronic discoid lupus erythematosus.
Topics: Chloroquine; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Porphyrias | 1954 |
Acute porphyria and coproporphyrinuria following chloroquine therapy; a report of two cases.
Topics: Chloroquine; Coproporphyria, Hereditary; Humans; Porphyria, Acute Intermittent; Porphyrias; Porphyri | 1957 |
Porphyria cutanea tarda; report of case successfully treated with chloroquine.
Topics: Animals; Chloroquine; Humans; Porifera; Porphyria Cutanea Tarda; Porphyrias; Skin Diseases | 1957 |
Porphyria during chloroquine therapy.
Topics: Chloroquine; Lupus Erythematosus, Systemic; Porphyrias | 1959 |
[On the drug modification of experimental porphyria in rabbits].
Topics: Animals; Ascorbic Acid; Chloroquine; Lagomorpha; Porphyrias; Rabbits; Thyroxine; Vitamins | 1960 |
Relapses of porphyria induced by chloroquine (aralen) phosphate; report of a case.
Topics: Chloroquine; Humans; Minnesota; Phosphates; Porphyrias; Recurrence | 1960 |
Porphyria in the Bantu and some observations on the effect of chloroquine.
Topics: Animals; Black People; Chloroquine; Humans; Porifera; Porphyrias | 1961 |
[THERAPEUTIC EFFECTIVENESS OF SOME DRUG SUBSTANCES AND THE CONTENT OF WATER-SOLUBLE VITAMINS IN PATIENTS WITH PHOTODERMATOSES].
Topics: Chloroquine; Eczema; Humans; Niacin; Nicotinic Acids; Photosensitivity Disorders; Porphyrias; Prurig | 1964 |
ENZYMES AND DRUG SENSITIVITY. DRUG AND ENZYME INTERACTIONS IN PORPHYRIAS.
Topics: Acetates; Adenine Nucleotides; Amides; Barbiturates; Chloroquine; Enzyme Inhibitors; Hexachlorocyclo | 1964 |
[A CASE OF PORPHYRIA CONGENITA].
Topics: Child; Chloroquine; Corrinoids; Drug Therapy; Humans; Pathology; Porphyria, Erythropoietic; Porphyri | 1964 |
[THERAPEUTIC EXPERIENCES WITH RESOCHIN AND RESOCHIN-CONTAINING PREPARATIONS IN DERMATOLOGICAL PATIENTS].
Topics: Carcinoma, Squamous Cell; Chloroquine; Drug Eruptions; Drug Therapy; Finger Injuries; Hematoma; Herp | 1964 |
EFFECTS OF CHLOROQUINE ON PATIENTS WITH CUTANEOUS PORPHYRIA OF THE "SYMPTOMATIC" TYPE.
Topics: Amino Acids; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chloroquine; Class | 1965 |
[Morphology of liver damage in chronic hepatic porphyria with special reference to the effect of therapy].
Topics: Adult; Aged; Biopsy; Bloodletting; Chloroquine; Female; Humans; Inclusion Bodies; Liver; Liver Disea | 1984 |
Porphyria variegata: failure of chloroquin treatment.
Topics: Adult; Chloroquine; Female; Humans; Porphyrias; Porphyrins; Skin Diseases | 1980 |
[Porphyria cutanea tarda (PCT)].
Topics: Bloodletting; Chloroquine; Diagnosis, Differential; Female; Humans; Liver Diseases; Male; Porphyrias | 1983 |
Low-dose oral chloroquine in the treatment of porphyria cutanea tarda.
Topics: Administration, Oral; Adult; Aged; Chloroquine; Drug Administration Schedule; Humans; Male; Middle A | 1984 |
[Clinico-immunological substantiation of the therapeutic effectiveness of delagil in porphyria cutanea tarda].
Topics: Chloroquine; Humans; Porphyrias; Skin Diseases | 1984 |
[Porphyria cutanea tarda and chronic lymphatic leukemia].
Topics: Bloodletting; Chloroquine; Combined Modality Therapy; Humans; Leukemia, Lymphoid; Lymph Nodes; Male; | 1984 |
[Immunological aspects of porphyria cutanea tarda].
Topics: Adult; Aged; Chloroquine; Female; Humans; Lymphocyte Activation; Male; Middle Aged; Porphyrias; Rose | 1983 |
[Major hypertrichosis in an adult female secondary to porphyria cutanea tarda. Its evolution with chloroquine].
Topics: Chloroquine; Female; Humans; Hypertrichosis; Middle Aged; Porphyrias; Skin Diseases; Uroporphyrins | 1983 |
Studies on in vitro formation of complexes between porphyrins and chloroquine.
Topics: Chloroquine; Chromatography, Gel; Humans; Porphyrias; Porphyrins; Skin Diseases; Spectrophotometry; | 1983 |
[Delagil treatment of urocoproporphyria].
Topics: Adult; Chloroquine; Coproporphyrins; Drug Evaluation; Edetic Acid; Female; Humans; Inosine; Male; Mi | 1980 |
Porphyria cutanea tarda and pregnancy.
Topics: Adult; Chloroquine; Female; Humans; Porphyrias; Porphyrins; Pregnancy; Pregnancy Complications; Skin | 1983 |
Chloroquine in treatment of porphyria cutanea tarda. Long-term efficacy of combined phlebotomy and high-dose chloroquine therapy.
Topics: Adult; Aged; Bloodletting; Chloroquine; Female; Follow-Up Studies; Humans; Liver; Male; Middle Aged; | 1982 |
[Effect of chloroquine in porphyria cutanea tarda].
Topics: Adult; Aged; Alcohol Drinking; Chloroquine; Coproporphyrins; Humans; Liver Function Tests; Male; Mid | 1980 |
[The effect of chloroquine therapy on the level of porphyrins in the liver in symptomatic hepatic porphyria].
Topics: Adult; Aged; Chloroquine; Humans; Liver; Liver Diseases; Middle Aged; Porphyrias | 1982 |
The liver in Ethiopians with porphyria cutanea tarda.
Topics: Adult; Aged; Alcohol Drinking; Biopsy; Chloroquine; Ethiopia; Female; Humans; Inflammation; Liver; L | 1982 |
Long-term treatment of porphyria cutanea tarda with low chloroquine doses.
Topics: Adult; Chloroquine; Dose-Response Relationship, Drug; Humans; Liver Diseases; Male; Middle Aged; Por | 1981 |
Porphyria Cutanea tarda in Missouri.
Topics: Chloroquine; Humans; Porphyrias; Skin Diseases | 1981 |
[Prolonged low-dose chloroquin therapy of porphyria cutanea tarda].
Topics: Adult; Chloroquine; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Porphyrias; Skin Di | 1981 |
Chloroquine in the treatment of porphyria cutanea tarda.
Topics: Adult; Aged; Chloroquine; Female; Humans; Male; Middle Aged; Porphyrias; Porphyrins; Skin Diseases | 1981 |
[Chloroquine in the treatment of porphyria cutanea tarda symptomatica. Twelve years of experience in 307 patients (author's transl)].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chloroquine; Female; Humans; Infant; Liver Disease | 1981 |
[Suburoporphyrins in symptomatic hepatic porphyria and in experimental porphyria (author's transl)].
Topics: Adult; Aged; Animals; Chloroquine; Female; Humans; Liver Diseases; Male; Middle Aged; Porphyrias; Po | 1981 |
Immunological and biochemical findings in patients with porphyria cutanea tarda.
Topics: Adult; Aged; Chloroquine; Complement System Proteins; Female; Humans; Immunoglobulin G; Male; Middle | 1981 |
Liver changes in porphyria cutanea tarda patients treated with chloroquine.
Topics: Adult; Aged; Chloroquine; Female; Humans; Liver; Male; Middle Aged; Porphyrias; Skin Diseases | 1980 |
[Influence of chloroquine on the hexachlorobenzene-induced porphyria. Investigations in the skin, liver, and urine (author's transl)].
Topics: Animals; Chloroquine; Female; Hexachlorobenzene; Iron; Liver; Porphyrias; Porphyrins; Rats; Skin | 1980 |
[Combination therapy of porphyria cutanea tarda using chloroquine and bloodletting therapy].
Topics: Adult; Aged; Bloodletting; Chloroquine; Female; Humans; Liver; Male; Middle Aged; Porphyrias | 1980 |
[Acute intermittent porphyria detected during treatment of malaria with chloroquine].
Topics: Acute Disease; Adult; Chloroquine; Diagnosis, Differential; Diagnostic Errors; Humans; Malaria; Male | 1980 |
[Treatment of porphyria cutanea tarda with intermittent chloroquine].
Topics: Chloroquine; Drug Administration Schedule; Female; Humans; Male; Porphyrias; Porphyrins; Skin Diseas | 1980 |
[Modern internal therapy of skin diseases (author's transl)].
Topics: Anti-Inflammatory Agents; Carotenoids; Chloroquine; Cyclooxygenase Inhibitors; Glucocorticoids; Huma | 1979 |
[Porphyria cutanea tarda: possible treatment and its results (author's transl)].
Topics: 4-Aminobenzoic Acid; Bloodletting; Chloroquine; Female; Humans; Male; Porphyrias; Porphyrins; Time F | 1978 |
Management of porphyria cutanea tarda.
Topics: Aged; Chloroquine; Female; Humans; Porphyrias; Skin Diseases, Vesiculobullous | 1977 |
Porphyria cutanea tarda: clinical and laboratory features.
Topics: Adult; Aged; Aspartate Aminotransferases; Bloodletting; Chloroquine; Estrogens; Ethanol; Female; Fer | 1979 |
Porphyria cutanea tarda. Clinical features and laboratory findings in 40 patients.
Topics: Adult; Aged; Alcohol Drinking; Bloodletting; Child; Chloroquine; Contraceptives, Oral; Diabetes Comp | 1979 |
[Clinic and treatment of porphyria cutanea tarda (author's transl)].
Topics: Bloodletting; Chloroquine; Female; Humans; Male; Porphyrias | 1979 |
[Porphyria cutanea tarda].
Topics: Adult; Aged; Bloodletting; Chloroquine; Diagnosis, Differential; Female; Humans; Hypertrichosis; Liv | 1979 |
[Porphyria cutanea tarda treated with low doses of antimalarial agents; liver findings (author's transl)].
Topics: Adult; Aged; Chloroquine; Drug Tolerance; Female; Humans; Liver; Liver Diseases; Male; Middle Aged; | 1977 |
Photosensitivity after treatment of porphyria cutanea tarda with low dose chloroquine.
Topics: Aged; Chloroquine; Drug Administration Schedule; Humans; Male; Photosensitivity Disorders; Porphyria | 1978 |
[Therapy of porphyria cutanea tarda using chloroquine].
Topics: Adult; Chloroquine; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Porphyrias; Rem | 1978 |
[Porphyria erythropoietica congenita Günther and chloroquine (author's transl)].
Topics: Child; Chloroquine; Elasticity; Erythrocytes; Erythropoiesis; Humans; Male; Photosensitivity Disorde | 1978 |
Porphyria variegata. Study of a large kindred in the United States.
Topics: Adolescent; Adult; Aged; Child; Chloroquine; Coproporphyrins; Feces; Female; Humans; Male; Middle Ag | 1978 |
Chloroquine in the treatment of porphyria cutanea tarda. Case report.
Topics: Aged; Chloroquine; Female; Humans; Porphyrias | 1977 |
Chloroquine in the treatment of porphyria cutanea tarda.
Topics: Chloroquine; Humans; Porphyrias; Remission, Spontaneous; Time Factors | 1977 |
Study of the effects of certain drugs on experimental porphyria in rats.
Topics: Animals; Chloroquine; Dicarbethoxydihydrocollidine; Ethanol; Griseofulvin; Liver; Phenobarbital; Por | 1977 |
[Effect of chloroquine on porphyrin transport in serum and liver cells (author's transl)].
Topics: Adult; Binding Sites; Biological Transport; Chloroquine; Humans; Liver; Middle Aged; Porphyrias; Por | 1977 |
The treatment of cutaneous porphyria.
Topics: Chloroquine; Humans; Penicillamine; Porphyrias | 1977 |
Treatment of porphyria cutanea tarda with chloroquine and phlebotomy.
Topics: Adult; Aged; Bloodletting; Chloroquine; Female; Humans; Male; Middle Aged; Porphyrias; Porphyrins | 1977 |
An unusual reaction to chloroquine-primaquine.
Topics: Adult; Chloroquine; Coproporphyrins; Female; Humans; Malaria; Porphyrias; Primaquine; Uroporphyrins | 1976 |
[Hydroa vacciniforme Bazin].
Topics: Adolescent; Adult; Amino Acids; Antimalarials; Carotenoids; Child; Child, Preschool; Chloroquine; Di | 1975 |
Letter: Retreatment with chloroquine in porphyria cutanea tarda.
Topics: Administration, Oral; Chloroquine; Humans; Porphyrias; Recurrence | 1975 |
[Accident in treatment of porphyria cutanea tarda by chloroquine (Resochin) (author's transl)].
Topics: Aminolevulinic Acid; Chloroquine; Humans; Liver; Male; Medication Errors; Middle Aged; Mitochondria, | 1976 |
Effective control of patients with porphyria cutanea tarda by measuring plasma uroporphyrin.
Topics: Adult; Aged; Aged, 80 and over; Bloodletting; Chloroquine; Female; Humans; Male; Middle Aged; Porphy | 1991 |
Skin morphology in porphyria cutanea tarda does not improve despite clinical remission.
Topics: Adult; Chloroquine; Female; Humans; Male; Middle Aged; Porphyrias; Remission Induction; Skin; Skin D | 1991 |
[Iron metabolism and chloroquine phosphate therapy in porphyria cutanea tarda].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chloroquine; Female; Humans; Iron; Male; Porphyrias; | 1990 |
Porphyria cutanea tarda due to ferrous gluconate.
Topics: Aged; Chloroquine; Female; Ferrous Compounds; Humans; Porphyrias; Porphyrins | 1990 |
[Results of treatment of porphyria cutanea tarda with bloodletting and chloroquine].
Topics: Administration, Oral; Adult; Aged; Bloodletting; Chloroquine; Combined Modality Therapy; Dose-Respon | 1990 |
[Artefacts in porphyria cutanea tarda].
Topics: Bloodletting; Chloroquine; Combined Modality Therapy; Diagnosis, Differential; Humans; Male; Malinge | 1990 |
[Porphyria cutanea tarda and lupus erythematosus].
Topics: Adult; Biopsy; Chloroquine; Cyclophosphamide; Humans; Kidney; Liver; Liver Function Tests; Lupus Ery | 1989 |
[Experimental study of the action of antimalarial agents with respect to therapy in porphyria. Combined effect of chloroquine and pyrimethamine].
Topics: Chloroquine; Humans; Porphyrias; Porphyrins; Pyrimethamine; Saccharomyces cerevisiae | 1989 |
[Therapeutic and pathogenetic aspects of porphyria cutanea tarda].
Topics: Alcoholism; Chloroquine; Contraceptives, Oral, Hormonal; Dose-Response Relationship, Drug; Drug Admi | 1986 |
[2 years' experience with combined therapy of symptomatic liver porphyria using pyrimethamine and chloroquine].
Topics: Adult; Chloroquine; Drug Therapy, Combination; Female; Humans; Liver Diseases; Male; Middle Aged; Po | 1988 |
Long-term effect of high-dose, short-course chloroquine therapy on porphyria cutanea tarda.
Topics: Adult; Aged; Chloroquine; Ethiopia; Female; Humans; Liver; Male; Middle Aged; Porphyrias; Skin Disea | 1987 |
The porphyrias.
Topics: Adolescent; Adult; Aminolevulinic Acid; beta Carotene; Bloodletting; Carotenoids; Child; Child, Pres | 1986 |
Two cases of infantile porphyria cutanea tarda: successful treatment with oral S-adenosyl-L-methionine and low-dose oral chloroquine.
Topics: Child; Chloroquine; Female; Humans; Male; Porphyrias; Porphyrins; S-Adenosylmethionine; Skin Disease | 1987 |
[Death following administration of 1,250 mg chloroquine in porphyria cutanea tarda].
Topics: Adult; Chloroquine; Dose-Response Relationship, Drug; Female; Humans; Liver; Medication Errors; Porp | 1986 |
Effects of chloroquine and hydroxychloroquine on the hexachlorobenzene-induced porphyria in rats.
Topics: Animals; Chlorobenzenes; Chloroquine; Female; Hexachlorobenzene; Hydroxychloroquine; Porphyrias; Rat | 1986 |
Porphyria cutanea tarda simulating scleroderma.
Topics: Chloroquine; Diagnosis, Differential; Female; Humans; Middle Aged; Porphyrias; Scleroderma, Systemic | 1987 |
Treatment of chronic hepatic porphyria (PCT).
Topics: Bloodletting; Chloroquine; Humans; Hydroxychloroquine; Liver Diseases; Porphyrias | 1986 |
Treatment of porphyria cutanea tarda.
Topics: Chloroquine; Humans; Porphyrias; Skin Diseases | 1987 |
[Experience with the therapy of symptomatic liver porphyria using a combination of antimalarial agents--chloroquine with pyrimethamine].
Topics: Adult; Aged; Chloroquine; Drug Therapy, Combination; Humans; Liver Diseases; Male; Middle Aged; Porp | 1987 |
Porphyria cutanea tarda symptomatica.
Topics: Adolescent; Chloroquine; Female; Humans; Porphyrias; Porphyrins; Skin Diseases | 1985 |
Influence of chloroquine on the porphyrin metabolism.
Topics: 7-Alkoxycoumarin O-Dealkylase; Aminolevulinic Acid; Aminopyrine N-Demethylase; Animals; Aryl Hydroca | 1985 |
Porphyria cutanea tarda symptomatica in children treated with chloroquine. Report of four cases with control liver biopsies.
Topics: Adolescent; Child; Chloroquine; Humans; Liver; Male; Porphyrias; Skin Diseases | 1985 |
Photodynamic action of uroporphyrin on the complement system in porphyria cutanea tarda.
Topics: Aged; beta Carotene; Carotenoids; Chloroquine; Complement Activation; Complement C3; Complement Syst | 1985 |
Proceedings: Porphyria cutanea tarda.
Topics: Adult; Chloroquine; Female; Humans; Porphyrias; Skin Diseases | 1974 |
Peripheral clinical laboratory service for the Border and Transkei.
Topics: Afibrinogenemia; Amebiasis; Balantidiasis; Black or African American; Black People; Cantharidin; Chi | 1973 |
[A case of chloroquine-induced porphyrinuria].
Topics: Acute Disease; Arthritis, Rheumatoid; Chloroquine; Female; Humans; Middle Aged; Porphyrias; Porphyri | 1973 |
Incorporation of (4-14 C) -aminolaevulinate into urinary porphyrins in porphyria cutanea tarda: effect of chloroquine therapy.
Topics: Adult; Aged; Autopsy; Carbon Isotopes; Carboxylic Acids; Chloroquine; Decarboxylation; Feces; Humans | 1973 |
[Therapy of patients with porphyria cutanea tarda with antimalarials].
Topics: Adult; Aged; Chloroquine; Female; Humans; Male; Middle Aged; Porphyrias; Time Factors; Transaminases | 1973 |
The therapeutic effect of chloroquine. Hepatic recovery in porphyria cutanea tarda.
Topics: Alanine Transaminase; Chloroquine; Female; Humans; Liver; Middle Aged; Mitochondria, Liver; Porphyri | 1973 |
The molecular basis of the action of chloroquine in porphyria cutanea tarda.
Topics: 5-Aminolevulinate Synthetase; Animals; Chemical Phenomena; Chemistry; Chloroquine; Chromatography, G | 1973 |
Treatment of porphyria cutanea tarda with chloroquine.
Topics: Administration, Oral; Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Chloroquine; F | 1974 |
Current concepts of cutaneous porphyria and its treatment with particular reference to the use of sodium calciumedetate.
Topics: Australia; Barbiturates; Chloroquine; Cholestyramine Resin; Diet Therapy; Edetic Acid; Estrogens; Gr | 1970 |
Studies on low dose chloroquine therapy and the action of chloroquine in symptomatic porphyria.
Topics: Adult; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chloroquine; Deferoxamine; Humans | 1972 |
[Chloroquine therapy in porphyria cutanea tarda].
Topics: Aged; Bloodletting; Chloroquine; Eosinophilia; Female; Humans; Male; Middle Aged; Porphyrias; Porphy | 1971 |
Evaluation of therapy in acquired porphyria cutanea tarda.
Topics: Adenosine Monophosphate; Adult; Chelating Agents; Chloroquine; Humans; Porphyrias; Pyridoxal Phospha | 1971 |
Biochemical effects of chloroquine therapy in porphyria cutanea tarda.
Topics: Ascites; Body Temperature; Chemical and Drug Induced Liver Injury; Chloroquine; Chromatography; Fece | 1970 |
Porphyria cutanea tarda.
Topics: Adult; Chloroquine; Humans; Male; Porphyrias; Porphyrins | 1970 |
The treatment of cutaneous porphyria with chloroquine or D-penicillamine.
Topics: Chloroquine; Humans; Penicillamine; Porphyrias; Porphyrins | 1970 |
Porphyria cutanea tarda. Remission following chloroquine administration without adverse effects.
Topics: Aged; Chloroquine; Feces; Female; Humans; Male; Porphyrias; Porphyrins; Pregnancy; Pregnancy Complic | 1968 |
Porphyria cutanea tarda treated with chloroquine phosphate.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Chloroquine; Humans; Male; Middle Aged; Porphyria | 1969 |
Effect of chloroquine on hepatic uroporphyrin metabolism in patients with porphyria cutanea tarda.
Topics: Adult; Aged; Chloroquine; Humans; Liver; Middle Aged; Porphyrias; Porphyrins; Skin Manifestations | 1966 |