chloroquine has been researched along with Porphyria, Acute Intermittent in 4 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Porphyria, Acute Intermittent: An autosomal dominant porphyria that is due to a deficiency of HYDROXYMETHYLBILANE SYNTHASE in the LIVER, the third enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features are recurrent and life-threatening neurologic disturbances, ABDOMINAL PAIN, and elevated level of AMINOLEVULINIC ACID and PORPHOBILINOGEN in the urine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Porphyria cutanea tarda can be effectively treated by phlebotomy or low dose chloroquine." | 4.81 | Management of acute and cutaneous porphyrias. ( Badminton, MN; Elder, GH, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DAVIS, MJ | 1 |
| PLOEG, DE | 1 |
| Puri, AS | 1 |
| Rawal, KK | 1 |
| Gupta, R | 1 |
| Broor, SL | 1 |
| Nordmann, Y | 1 |
| Puy, H | 1 |
| Deybach, JC | 1 |
| Badminton, MN | 1 |
| Elder, GH | 1 |
2 reviews available for chloroquine and Porphyria, Acute Intermittent
| Article | Year |
|---|---|
[Hepatic porphyria].
Topics: Adult; Analgesics, Opioid; Antipsychotic Agents; Charcoal; Child; Child, Preschool; Chloroquine; Chl | 1999 |
Management of acute and cutaneous porphyrias.
Topics: Arginine; beta Carotene; Chloroquine; Estrogens; Ethanol; Heme; Humans; Phlebotomy; Porphyria Cutane | 2002 |
2 other studies available for chloroquine and Porphyria, Acute Intermittent
| Article | Year |
|---|---|
Acute porphyria and coproporphyrinuria following chloroquine therapy; a report of two cases.
Topics: Chloroquine; Coproporphyria, Hereditary; Humans; Porphyria, Acute Intermittent; Porphyrias; Porphyri | 1957 |
Precipitation of acute intermittent porphyria by chloroquin.
Topics: Child; Chloroquine; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration S | 1996 |