chloroquine has been researched along with Polyuria in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Polyuria: Urination of a large volume of urine with an increase in urinary frequency, commonly seen in diabetes (DIABETES MELLITUS; DIABETES INSIPIDUS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, its adverse effect has been limiting its long-term use in clinic." | 1.56 | Chloroquine attenuates lithium-induced NDI and proliferation of renal collecting duct cells. ( Cao, W; Chen, S; Du, Y; Guo, Y; Huang, S; Jia, Z; Jiang, M; Qian, Y; Tang, X; Yang, B; Zhang, A; Zhang, Y, 2020) |
| " Chronic administration of chloroquine also results in polyuria, which may be explained by suppression of the antidiuretic response of vasopressin." | 1.38 | Chronic use of chloroquine disrupts the urine concentration mechanism by lowering cAMP levels in the inner medulla. ( Blount, MA; von Bergen, TN, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Du, Y | 1 |
| Qian, Y | 1 |
| Tang, X | 1 |
| Guo, Y | 1 |
| Chen, S | 1 |
| Jiang, M | 1 |
| Yang, B | 1 |
| Cao, W | 1 |
| Huang, S | 1 |
| Zhang, A | 1 |
| Jia, Z | 1 |
| Zhang, Y | 1 |
| von Bergen, TN | 1 |
| Blount, MA | 1 |
2 other studies available for chloroquine and Polyuria
| Article | Year |
|---|---|
Chloroquine attenuates lithium-induced NDI and proliferation of renal collecting duct cells.
Topics: Animals; Aquaporin 2; Autophagy; beta Catenin; Cell Line; Cell Proliferation; Chloroquine; Diabetes | 2020 |
Chronic use of chloroquine disrupts the urine concentration mechanism by lowering cAMP levels in the inner medulla.
Topics: Animals; Aquaporin 2; Chloroquine; Cyclic AMP; Down-Regulation; Kidney; Kidney Concentrating Ability | 2012 |