chloroquine has been researched along with Polycystic Kidney, Autosomal Dominant in 1 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Polycystic Kidney, Autosomal Dominant: Kidney disorders with autosomal dominant inheritance and characterized by multiple CYSTS in both KIDNEYS with progressive deterioration of renal function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The molecular pathogenesis of ADPKD is not completely known, and there is no approved therapy." | 1.43 | Targeted rescue of a polycystic kidney disease mutation by lysosomal inhibition. ( Hofherr, A; Köttgen, M; Wagner, CJ; Watnick, T, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hofherr, A | 1 |
| Wagner, CJ | 1 |
| Watnick, T | 1 |
| Köttgen, M | 1 |
1 other study available for chloroquine and Polycystic Kidney, Autosomal Dominant
| Article | Year |
|---|---|
Targeted rescue of a polycystic kidney disease mutation by lysosomal inhibition.
Topics: Animals; Antirheumatic Agents; Chloroquine; Drosophila melanogaster; Drug Evaluation, Preclinical; F | 2016 |