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chloroquine and Poliomyelitis

chloroquine has been researched along with Poliomyelitis in 2 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Poliomyelitis: An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)

Research Excerpts

ExcerptRelevanceReference
"The immune response of 198 young Nigerian children protected against malaria by chemoprophylaxis with chloroquine to immunization with triple, poliomyelitis, measles, typhoid, meningococcal and BCG vaccines was compared with the immune response to vaccination of 185 control children."9.05Malaria chemoprophylaxis with chloroquine in young Nigerian children. II. Effect on the immune response to vaccination. ( Bartlett, A; Bidwell, DE; Bradley, AK; Bradley-Moore, AM; Craske, J; Gilles, HM; Greenwood, BM; Kirkwood, BR; Voller, A, 1985)
"The immune response of 198 young Nigerian children protected against malaria by chemoprophylaxis with chloroquine to immunization with triple, poliomyelitis, measles, typhoid, meningococcal and BCG vaccines was compared with the immune response to vaccination of 185 control children."5.05Malaria chemoprophylaxis with chloroquine in young Nigerian children. II. Effect on the immune response to vaccination. ( Bartlett, A; Bidwell, DE; Bradley, AK; Bradley-Moore, AM; Craske, J; Gilles, HM; Greenwood, BM; Kirkwood, BR; Voller, A, 1985)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bradley-Moore, AM1
Greenwood, BM1
Bradley, AK1
Bartlett, A1
Bidwell, DE1
Voller, A1
Craske, J1
Kirkwood, BR1
Gilles, HM1
Woodruff, AW1

Trials

1 trial available for chloroquine and Poliomyelitis

ArticleYear
Malaria chemoprophylaxis with chloroquine in young Nigerian children. II. Effect on the immune response to vaccination.
    Annals of tropical medicine and parasitology, 1985, Volume: 79, Issue:6

    Topics: Antibody Formation; BCG Vaccine; Child, Preschool; Chloroquine; Diphtheria; Humans; Immunity, Cellul

1985

Other Studies

1 other study available for chloroquine and Poliomyelitis

ArticleYear
Current practice in tropical medicine.
    Transactions of the Medical Society of London, 1969, Volume: 85

    Topics: Acute Kidney Injury; Amebiasis; Amebicides; Chloroquine; Cholera; Drug Resistance, Microbial; Hepati

1969