chloroquine has been researched along with Placenta Diseases in 17 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Placenta Diseases: Pathological processes or abnormal functions of the PLACENTA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effect of chloroquine chemoprophylaxis during pregnancy on birth weights, a randomized trial was carried out in 1987 and 1988 in Banfora, Burkina Faso (West Africa)." | 9.07 | Effect of chloroquine chemoprophylaxis during pregnancy on birth weight: results of a randomized trial. ( Barro, D; Breart, G; Carnevale, P; Cot, M; Roisin, A; Verhave, JP; Yada, A, 1992) |
| "In West Africa, treatment for the prevention of malaria during pregnancy has recently changed from chloroquine (CQ) prophylaxis to intermittent preventive treatment (IPTp)." | 7.74 | Efficacy of intermittent preventive treatment versus chloroquine prophylaxis to prevent malaria during pregnancy in Benin. ( Briand, V; Cot, M; Denoeud, L; Massougbodji, A, 2008) |
| "Chloroquine was given under observation at a weekly oral dose of 300 mg." | 6.68 | Increase of birth weight following chloroquine chemoprophylaxis during the first pregnancy: results of a randomized trial in Cameroon. ( Breart, G; Cot, M; Esveld, M; Etya'ale, D; Le Hesran, JY; Miailhes, P, 1995) |
| "The weekly chemoprophylaxis of malaria during pregnancy with chloroquine (CQ) has become problematic with the increasing resistance of Plasmodium falciparum to this drug." | 5.14 | Placental malaria and low birth weight in pregnant women living in a rural area of Burkina Faso following the use of three preventive treatment regimens. ( Bougouma, EC; Diarra, A; Konaté, AT; Nébié, I; Ouedraogo, A; Sirima, SB; Tiono, AB, 2009) |
| " The purpose was to compare the efficacy of two regimens using chloroquine (CQ) or sulfadoxine-pyrimethamine (SP) during pregnancy and delivery in a village located in an endemic area of Mali." | 5.12 | [Randomized clinical trial of two malaria prophylaxis regimens for pregnant women in Faladie, Mali]. ( Dabo, CA; Diallo, M; Diarra, MA; Doumbo, O; Kayentao, K; Ongoiba, A; Sangho, H; Saye, R; Yattara, O, 2007) |
| "In Mali, IPT with SP appears more efficacious than weekly chloroquine chemoprophylaxis in preventing malaria during pregnancy." | 5.11 | Comparison of intermittent preventive treatment with chemoprophylaxis for the prevention of malaria during pregnancy in Mali. ( Coulibaly, D; Doumbo, O; Doumtabe, D; Kayentao, K; Keita, AS; Kodio, M; Maiga, B; Maiga, H; Mungai, M; Newman, RD; Ongoiba, A; Parise, ME, 2005) |
| "To define an effective and deliverable antimalarial regimen for use during pregnancy, pregnant women at highest risk of malaria (those in their first or second pregnancy) in an area of Malawi with high transmission of chloroquine (CQ)-resistant Plasmodium falciparum were placed on CQ and/or sulfadoxine-pyrimethamine (SP)." | 5.07 | The efficacy of antimalarial regimens containing sulfadoxine-pyrimethamine and/or chloroquine in preventing peripheral and placental Plasmodium falciparum infection among pregnant women in Malawi. ( Chitsulo, L; Kazembe, P; Macheso, A; Schultz, LJ; Steketee, RW; Wirima, JJ, 1994) |
| "To determine the effect of chloroquine chemoprophylaxis during pregnancy on birth weights, a randomized trial was carried out in 1987 and 1988 in Banfora, Burkina Faso (West Africa)." | 5.07 | Effect of chloroquine chemoprophylaxis during pregnancy on birth weight: results of a randomized trial. ( Barro, D; Breart, G; Carnevale, P; Cot, M; Roisin, A; Verhave, JP; Yada, A, 1992) |
| "In West Africa, treatment for the prevention of malaria during pregnancy has recently changed from chloroquine (CQ) prophylaxis to intermittent preventive treatment (IPTp)." | 3.74 | Efficacy of intermittent preventive treatment versus chloroquine prophylaxis to prevent malaria during pregnancy in Benin. ( Briand, V; Cot, M; Denoeud, L; Massougbodji, A, 2008) |
| "6 months of pregnancy), placed on one of three chloroquine regimens, and followed through delivery." | 3.69 | Impairment of a pregnant woman's acquired ability to limit Plasmodium falciparum by infection with human immunodeficiency virus type-1. ( Bloland, PB; Breman, JG; Chilima, B; Chitsulo, L; Mermin, JH; Steketee, RW; Wirima, JJ, 1996) |
| "Chloroquine was given under observation at a weekly oral dose of 300 mg." | 2.68 | Increase of birth weight following chloroquine chemoprophylaxis during the first pregnancy: results of a randomized trial in Cameroon. ( Breart, G; Cot, M; Esveld, M; Etya'ale, D; Le Hesran, JY; Miailhes, P, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 6 (35.29) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boudová, S | 1 |
| Divala, T | 1 |
| Mungwira, R | 1 |
| Mawindo, P | 1 |
| Tomoka, T | 1 |
| Laufer, MK | 1 |
| Sharma, L | 1 |
| Shukla, G | 1 |
| Briand, V | 1 |
| Denoeud, L | 1 |
| Massougbodji, A | 1 |
| Cot, M | 3 |
| Tiono, AB | 1 |
| Ouedraogo, A | 1 |
| Bougouma, EC | 1 |
| Diarra, A | 1 |
| Konaté, AT | 1 |
| Nébié, I | 1 |
| Sirima, SB | 1 |
| Ndao, CT | 1 |
| Ndiaye, JL | 1 |
| Gaye, A | 1 |
| Le Hesran, JY | 2 |
| Kayentao, K | 2 |
| Kodio, M | 1 |
| Newman, RD | 1 |
| Maiga, H | 1 |
| Doumtabe, D | 1 |
| Ongoiba, A | 2 |
| Coulibaly, D | 1 |
| Keita, AS | 1 |
| Maiga, B | 1 |
| Mungai, M | 1 |
| Parise, ME | 1 |
| Doumbo, O | 2 |
| Mehlotra, RK | 1 |
| Mattera, G | 1 |
| Bhatia, K | 1 |
| Reeder, JC | 1 |
| Stoneking, M | 1 |
| Zimmerman, PA | 1 |
| Diallo, M | 1 |
| Dabo, CA | 1 |
| Saye, R | 1 |
| Yattara, O | 1 |
| Diarra, MA | 1 |
| Sangho, H | 1 |
| Flici, O | 1 |
| Tadjerouni, A | 1 |
| Leroy, F | 1 |
| Teys, JP | 1 |
| Hubinont, PO | 1 |
| Schultz, LJ | 1 |
| Steketee, RW | 4 |
| Macheso, A | 1 |
| Kazembe, P | 1 |
| Chitsulo, L | 2 |
| Wirima, JJ | 4 |
| Mutabingwa, TK | 1 |
| Eling, WM | 1 |
| Kitinya, JN | 1 |
| Malle, LN | 1 |
| de Geus, A | 1 |
| Miailhes, P | 1 |
| Esveld, M | 1 |
| Etya'ale, D | 1 |
| Breart, G | 2 |
| Slutsker, L | 1 |
| Roberts, JM | 1 |
| Khoromana, CO | 1 |
| Heymann, DL | 2 |
| Breman, JG | 2 |
| Bloland, PB | 1 |
| Chilima, B | 1 |
| Mermin, JH | 1 |
| Staalsoe, T | 1 |
| Megnekou, R | 1 |
| Fievét, N | 1 |
| Ricke, CH | 1 |
| Zornig, HD | 1 |
| Leke, R | 1 |
| Taylor, DW | 1 |
| Deloron, P | 1 |
| Hviid, L | 1 |
| Roisin, A | 1 |
| Barro, D | 1 |
| Yada, A | 1 |
| Verhave, JP | 1 |
| Carnevale, P | 1 |
| McDermott, JM | 1 |
| Macheso, AP | 1 |
| Wahl, RD | 1 |
| Campbell, CC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intermittent Preventive Treatment During Pregnancy in Benin: a Randomized, Open, and Equivalent Trial Comparing Sulfadoxine-Pyrimethamine With Mefloquine[NCT00274235] | Phase 3 | 1,600 participants (Anticipated) | Interventional | 2005-07-31 | Completed | ||
| Intermittent Preventive Treatment With Azithromycin-containing Regimens for the Prevention of Malarial Infections and Anaemia and the Control of Sexually Transmitted Infections in Pregnant Women in Papua New Guinea[NCT01136850] | Phase 3 | 2,793 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for chloroquine and Placenta Diseases
| Article | Year |
|---|---|
[Malaria in pregnant women. Presentation of 2 cases and review of the literature].
Topics: Abortion, Spontaneous; Acute Kidney Injury; Adult; Anemia, Hemolytic; Antimalarials; Brain Diseases; | 1982 |
10 trials available for chloroquine and Placenta Diseases
| Article | Year |
|---|---|
Placental but Not Peripheral Plasmodium falciparum Infection During Pregnancy Is Associated With Increased Risk of Malaria in Infancy.
Topics: Chloroquine; Drug Combinations; Female; Follow-Up Studies; Humans; Infant; Logistic Models; Longitud | 2017 |
Placental malaria and low birth weight in pregnant women living in a rural area of Burkina Faso following the use of three preventive treatment regimens.
Topics: Adult; Animals; Antimalarials; Burkina Faso; Chemoprevention; Chloroquine; Drug Combinations; Female | 2009 |
Comparison of intermittent preventive treatment with chemoprophylaxis for the prevention of malaria during pregnancy in Mali.
Topics: Abortion, Spontaneous; Adolescent; Adult; Anemia; Birth Weight; Chemoprevention; Chloroquine; Drug A | 2005 |
[Randomized clinical trial of two malaria prophylaxis regimens for pregnant women in Faladie, Mali].
Topics: Adult; Anemia; Antimalarials; Chloroquine; Drug Combinations; Endemic Diseases; Female; Humans; Infa | 2007 |
The efficacy of antimalarial regimens containing sulfadoxine-pyrimethamine and/or chloroquine in preventing peripheral and placental Plasmodium falciparum infection among pregnant women in Malawi.
Topics: Analysis of Variance; Antimalarials; Chi-Square Distribution; Chloroquine; Drug Combinations; Drug T | 1994 |
Malaria chemosuppression in pregnancy. V. Placenta malarial changes among three different prophylaxis groups.
Topics: Chloroquine; Drug Therapy, Combination; Female; Humans; Malaria; Placenta Diseases; Pregnancy; Pregn | 1993 |
Increase of birth weight following chloroquine chemoprophylaxis during the first pregnancy: results of a randomized trial in Cameroon.
Topics: Adolescent; Adult; Animals; Antimalarials; Birth Weight; Cameroon; Chloroquine; Drug Resistance; Ery | 1995 |
Malaria parasite infection during pregnancy and at delivery in mother, placenta, and newborn: efficacy of chloroquine and mefloquine in rural Malawi.
Topics: Adolescent; Adult; Antimalarials; Chloroquine; Female; Fetal Blood; Humans; Malaria, Falciparum; Mal | 1996 |
Effect of chloroquine chemoprophylaxis during pregnancy on birth weight: results of a randomized trial.
Topics: Adult; Birth Weight; Burkina Faso; Chloroquine; Female; Humans; Malaria; Placenta Diseases; Pregnanc | 1992 |
Efficacy of chemoprophylaxis in preventing Plasmodium falciparum parasitaemia and placental infection in pregnant women in Malawi.
Topics: Amodiaquine; Animals; Chloroquine; Female; Humans; Malaria; Malawi; Placenta Diseases; Plasmodium fa | 1988 |
6 other studies available for chloroquine and Placenta Diseases
| Article | Year |
|---|---|
Treatment of pregnant BALB/c mice with sulphadoxine pyrimethamine or chloroquine abrogates Plasmodium berghei induced placental pathology.
Topics: Animals; Antimalarials; Antioxidants; Chloroquine; DNA Fragmentation; Drug Combinations; Female; Lip | 2014 |
Efficacy of intermittent preventive treatment versus chloroquine prophylaxis to prevent malaria during pregnancy in Benin.
Topics: Adult; Antimalarials; Benin; Chloroquine; Cross-Sectional Studies; Female; Humans; Infant, Low Birth | 2008 |
[Placental infection by Plasmodium falciparum in an urban area of Senegal].
Topics: Adolescent; Adult; Animals; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Middl | 2003 |
Insight into the early spread of chloroquine-resistant Plasmodium falciparum infections in Papua New Guinea.
Topics: Animals; Antimalarials; Chloroquine; DNA, Protozoan; Drug Resistance; Female; Genes, MDR; Humans; Ma | 2005 |
Impairment of a pregnant woman's acquired ability to limit Plasmodium falciparum by infection with human immunodeficiency virus type-1.
Topics: Adolescent; Adult; Antimalarials; Chloroquine; Delivery, Obstetric; Female; Fetal Blood; HIV Infecti | 1996 |
Acquisition and decay of antibodies to pregnancy-associated variant antigens on the surface of Plasmodium falciparum-infected erythrocytes that protect against placental parasitemia.
Topics: Animals; Antibodies, Protozoan; Antigens, Protozoan; Antimalarials; Cell Adhesion; Chloroquine; Chon | 2001 |