chloroquine has been researched along with Pituitary Neoplasms in 6 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine (CQ) is an old drug widely used to treat malaria." | 1.46 | Pituitary Tumor Suppression by Combination of Cabergoline and Chloroquine. ( Cao, L; Guo, YH; Leng, ZG; Lin, SJ; Shang, HB; Wu, ZB; Wu, ZR; Zhang, X; Zhang, Y; Zhao, WG, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, SJ | 1 |
| Wu, ZR | 1 |
| Cao, L | 1 |
| Zhang, Y | 1 |
| Leng, ZG | 1 |
| Guo, YH | 1 |
| Shang, HB | 1 |
| Zhao, WG | 1 |
| Zhang, X | 1 |
| Wu, ZB | 1 |
| Halpern, J | 1 |
| Hinkle, PM | 1 |
| Westendorf, JM | 1 |
| Schonbrunn, A | 2 |
| Steinsapir, J | 1 |
| Harney, J | 1 |
| Larsen, PR | 1 |
| Stoller, TJ | 1 |
| Shields, D | 1 |
| Presky, DH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Combined Treatment of Cabergoline With Hydroxychloroquine/Chloroquine for Resistant Prolactinomas[NCT03400865] | 30 participants (Anticipated) | Interventional | 2018-10-25 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for chloroquine and Pituitary Neoplasms
| Article | Year |
|---|---|
Pituitary Tumor Suppression by Combination of Cabergoline and Chloroquine.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cabergoline; Cell Death; Cells, Cultured; C | 2017 |
Evidence for an active step in thyroid hormone transport to nuclei: drug inhibition of L-125I-triiodothyronine binding to nuclear receptors in rat pituitary tumor cells.
Topics: Animals; Antineoplastic Agents; Biological Transport, Active; Cadaverine; Cell Line; Cell Nucleus; C | 1982 |
Characterization of bombesin receptors in a rat pituitary cell line.
Topics: Animals; Binding, Competitive; Bombesin; Cell Line; Chloroquine; Kinetics; Neoplasms, Experimental; | 1983 |
Type 2 iodothyronine deiodinase in rat pituitary tumor cells is inactivated in proteasomes.
Topics: Adenosine Triphosphate; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Chloroquine; Cycloheximi | 1998 |
The propeptide of preprosomatostatin mediates intracellular transport and secretion of alpha-globin from mammalian cells.
Topics: Animals; beta-Lactamases; Cell Line; Chloroquine; Globins; Kinetics; Pituitary Neoplasms; Protein Pr | 1989 |
Receptor-bound somatostatin and epidermal growth factor are processed differently in GH4C1 rat pituitary cells.
Topics: Ammonium Chloride; Animals; Cell Compartmentation; Cell Line; Cell Membrane; Chloroquine; Cytosol; E | 1986 |