chloroquine has been researched along with Parasitic Diseases, Animal in 1 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Parasitic Diseases, Animal: Animal diseases caused by PARASITES.
Excerpt | Relevance | Reference |
---|---|---|
"Introduction of water-solubilizing groups on the 5-phenyl ring of a 2-aminopyrazine series led to the identification of highly potent compounds against the blood life-cycle stage of the human malaria parasite Plasmodium falciparum." | 7.83 | Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle. ( Angulo-Barturen, I; Antonova-Koch, Y; Bashyam, S; Birkholtz, LM; Botha, ME; Charman, SA; Chibale, K; Ferrer, S; Gonzàlez Cabrera, D; Han, Z; Jiménez-Díaz, MB; Lawrence, N; Le Manach, C; Martínez, MS; Meister, S; Nchinda, AT; Nondaba, SH; Paquet, T; Reader, J; Street, LJ; Taylor, D; Waterson, D; White, KL; Winzeler, EA; Wittlin, S; Witty, MJ; Younis, Y; Zabiulla, M, 2016) |
"Introduction of water-solubilizing groups on the 5-phenyl ring of a 2-aminopyrazine series led to the identification of highly potent compounds against the blood life-cycle stage of the human malaria parasite Plasmodium falciparum." | 3.83 | Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle. ( Angulo-Barturen, I; Antonova-Koch, Y; Bashyam, S; Birkholtz, LM; Botha, ME; Charman, SA; Chibale, K; Ferrer, S; Gonzàlez Cabrera, D; Han, Z; Jiménez-Díaz, MB; Lawrence, N; Le Manach, C; Martínez, MS; Meister, S; Nchinda, AT; Nondaba, SH; Paquet, T; Reader, J; Street, LJ; Taylor, D; Waterson, D; White, KL; Winzeler, EA; Wittlin, S; Witty, MJ; Younis, Y; Zabiulla, M, 2016) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Le Manach, C | 1 |
Nchinda, AT | 1 |
Paquet, T | 1 |
Gonzàlez Cabrera, D | 1 |
Younis, Y | 1 |
Han, Z | 1 |
Bashyam, S | 1 |
Zabiulla, M | 1 |
Taylor, D | 1 |
Lawrence, N | 1 |
White, KL | 1 |
Charman, SA | 1 |
Waterson, D | 1 |
Witty, MJ | 1 |
Wittlin, S | 1 |
Botha, ME | 1 |
Nondaba, SH | 1 |
Reader, J | 1 |
Birkholtz, LM | 1 |
Jiménez-Díaz, MB | 1 |
Martínez, MS | 1 |
Ferrer, S | 1 |
Angulo-Barturen, I | 1 |
Meister, S | 1 |
Antonova-Koch, Y | 1 |
Winzeler, EA | 1 |
Street, LJ | 1 |
Chibale, K | 1 |
1 other study available for chloroquine and Parasitic Diseases, Animal
Article | Year |
---|---|
Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle.
Topics: Animals; Antimalarials; Disease Models, Animal; Dose-Response Relationship, Drug; Ether-A-Go-Go Pota | 2016 |