chloroquine has been researched along with Pancreatitis in 13 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined the effects of a weak base, chloroquine, on the trypsinogen processing in cerulein-induced pancreatitis." | 7.72 | The pH modulator chloroquine blocks trypsinogen activation peptide generation in cerulein-induced pancreatitis. ( Makuuchi, M; Matsukura, A; Otani, T; Seyama, Y, 2003) |
| "We have investigated the effect of in vivo chloroquine administration on both secretagogue and diet-induced experimental pancreatitis to determine if raising the pH of cytoplasmic vacuoles in these models of pancreatitis would have a protective effect." | 7.68 | The effect of chloroquine administration on two experimental models of acute pancreatitis. ( Dawra, R; Lerch, MM; Saluja, AK; Saluja, M; Steer, ML, 1993) |
| "We examined the effects of a weak base, chloroquine, on the trypsinogen processing in cerulein-induced pancreatitis." | 3.72 | The pH modulator chloroquine blocks trypsinogen activation peptide generation in cerulein-induced pancreatitis. ( Makuuchi, M; Matsukura, A; Otani, T; Seyama, Y, 2003) |
| "We have investigated the effect of in vivo chloroquine administration on both secretagogue and diet-induced experimental pancreatitis to determine if raising the pH of cytoplasmic vacuoles in these models of pancreatitis would have a protective effect." | 3.68 | The effect of chloroquine administration on two experimental models of acute pancreatitis. ( Dawra, R; Lerch, MM; Saluja, AK; Saluja, M; Steer, ML, 1993) |
| "Pretreatment with chloroquine, a phospholipase A2 inhibitor, led to a inhibition of TXB2 production, whereas 6-keto-PGF1 alpha and PGE2 levels showed a surprising slight elevation in the first 6 h." | 1.27 | Prostanoid imbalance in experimental acute necrotizing pancreatitis in rats. ( Kort, WJ; van Ooijen, B; Vincent, JE; Westbroek, DL; Wilson, JH; Zijlstra, FJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 2 |
| Liu, S | 1 |
| Liu, H | 1 |
| Yang, C | 2 |
| Jiang, A | 1 |
| Wei, H | 1 |
| Sun, D | 1 |
| Cai, Z | 1 |
| Zheng, Y | 2 |
| Hu, T | 1 |
| Cao, H | 1 |
| Zhou, P | 1 |
| He, G | 1 |
| Song, X | 1 |
| Tong, A | 1 |
| Guo, G | 1 |
| Yang, F | 1 |
| Zhang, X | 1 |
| Qian, Z | 1 |
| Qi, X | 1 |
| Zhou, L | 1 |
| Loncle, C | 1 |
| Molejon, MI | 1 |
| Lac, S | 1 |
| Tellechea, JI | 1 |
| Lomberk, G | 1 |
| Gramatica, L | 1 |
| Fernandez Zapico, MF | 1 |
| Dusetti, N | 1 |
| Urrutia, R | 1 |
| Iovanna, JL | 1 |
| Seyama, Y | 1 |
| Otani, T | 3 |
| Matsukura, A | 2 |
| Makuuchi, M | 1 |
| van Dijk, E | 1 |
| Leach, SD | 1 |
| Bilchik, AJ | 1 |
| Karapetian, O | 1 |
| Gorelick, FS | 1 |
| Modlin, IM | 1 |
| Lerch, MM | 1 |
| Saluja, AK | 1 |
| Dawra, R | 1 |
| Saluja, M | 1 |
| Steer, ML | 1 |
| Guillaumes, S | 1 |
| Blanco, I | 1 |
| Villanueva, A | 1 |
| Sans, MD | 1 |
| Clavé, P | 1 |
| Chabás, A | 1 |
| Farré, A | 1 |
| Lluís, F | 1 |
| Skuja, N | 1 |
| van Ooijen, B | 1 |
| Kort, WJ | 1 |
| Zijlstra, FJ | 1 |
| Vincent, JE | 1 |
| Wilson, JH | 1 |
| Westbroek, DL | 1 |
| Buianov, VM | 1 |
| Stupin, IV | 1 |
| Zheltikov, AN | 1 |
| Sherstnev, MP | 1 |
13 other studies available for chloroquine and Pancreatitis
| Article | Year |
|---|---|
Versatile cationic liposomes for RIP3 overexpression in colon cancer therapy and RIP3 downregulation in acute pancreatitis therapy.
Topics: Animals; Antimalarials; Arginine; Cell Line; Chemotherapy, Adjuvant; Chloroquine; Colonic Neoplasms; | 2020 |
Facile Construction of Chloroquine Containing PLGA-Based pDNA Delivery System for Efficient Tumor and Pancreatitis Targeting in Vitro and in Vivo.
Topics: Animals; Calorimetry, Differential Scanning; Chloroquine; HEK293 Cells; Humans; Lactic Acid; Male; M | 2015 |
The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation.
Topics: Animals; Autophagy; Carcinoma, Ductal; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroqu | 2016 |
The pH modulator chloroquine blocks trypsinogen activation peptide generation in cerulein-induced pancreatitis.
Topics: Animals; Ceruletide; Chloroquine; Enzyme Inhibitors; Fluorescent Antibody Technique; Hydrogen-Ion Co | 2003 |
[Pancreas irritation caused by oxyphenbutazone (Tanderil)].
Topics: Chloroquine; Female; Humans; Oxyphenbutazone; Pancreatitis | 1984 |
Influence of chloroquine on diet-induced pancreatitis.
Topics: Acute Disease; Amylases; Animals; Chloroquine; Choline; Diet; Ethionine; Female; Hydrogen-Ion Concen | 1993 |
The effect of chloroquine administration on two experimental models of acute pancreatitis.
Topics: Acute Disease; Animals; Cathepsin B; Chloroquine; Enzyme Activation; Hydrogen-Ion Concentration; Mal | 1993 |
Chloroquine stabilizes pancreatic lysosomes and improves survival of mice with diet-induced acute pancreatitis.
Topics: Acid Phosphatase; Acute Disease; Amylases; Animals; beta-N-Acetylhexosaminidases; Cathepsin B; Chlor | 1997 |
Chloroquine improves survival of mice with diet-induced acute pancreatitis.
Topics: Acute Disease; Animals; Chloroquine; Diet; Lysosomes; Mice; Pancreatitis; Survival Rate | 1998 |
pH modulator chloroquine prevents diet-induced acute pancreatitis.
Topics: Acute Disease; Animals; Chloroquine; Diet; Hydrogen-Ion Concentration; Mice; Pancreatitis | 2000 |
[Clinical aspects and therapy of chronic pancreatitis].
Topics: 4-Aminobenzoic Acid; Alcoholism; Amylases; Chloroquine; Chronic Disease; Chymotrypsin; Diabetes Mell | 1979 |
Prostanoid imbalance in experimental acute necrotizing pancreatitis in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Chloroquine; Chromones; Dinoprostone; Male; Ne | 1988 |
[Use of dibunol and delagil in the treatment of acute pancreatitis].
Topics: Acute Disease; Administration, Oral; Animals; Antioxidants; Butylated Hydroxytoluene; Chloroquine; D | 1988 |