chloroquine has been researched along with Ototoxicity in 3 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Ototoxicity: Damage to the EAR or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The suggested dose of chloroquine for COVID-19 infection is considerably higher than the usual dosage for malaria treatment; therefore, it is plausible that the ototoxic effects will be greater." | 6.66 | Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review. ( Baguley, DM; Kasbekar, AV; Prayuenyong, P, 2020) |
| "Aim of this paper is to remind the risk of ototoxicity when using chloroquine and hydroxychloroquine, in particular as prophylactic agents against SARS-CoV-2, during the pandemic." | 3.96 | Ototoxicity prevention during the SARS-CoV-2 (COVID-19) emergency. ( Ciorba, A; Hatzopoulos, S; Pelucchi, S; Skarżyński, PH, 2020) |
| " The suggested dose of chloroquine for COVID-19 infection is considerably higher than the usual dosage for malaria treatment; therefore, it is plausible that the ototoxic effects will be greater." | 2.66 | Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review. ( Baguley, DM; Kasbekar, AV; Prayuenyong, P, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prayuenyong, P | 1 |
| Kasbekar, AV | 1 |
| Baguley, DM | 1 |
| Davis, SN | 1 |
| Wu, P | 1 |
| Camci, ED | 1 |
| Simon, JA | 1 |
| Rubel, EW | 1 |
| Raible, DW | 1 |
| Ciorba, A | 1 |
| Skarżyński, PH | 1 |
| Pelucchi, S | 1 |
| Hatzopoulos, S | 1 |
1 review available for chloroquine and Ototoxicity
| Article | Year |
|---|---|
Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review.
Topics: Antimalarials; Antiviral Agents; Chloroquine; COVID-19 Drug Treatment; Emergencies; Hearing Loss; Hu | 2020 |
2 other studies available for chloroquine and Ototoxicity
| Article | Year |
|---|---|
Chloroquine kills hair cells in zebrafish lateral line and murine cochlear cultures: Implications for ototoxicity.
Topics: Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Chloroquine; Hair Cells, Auditory; Hydrox | 2020 |
Ototoxicity prevention during the SARS-CoV-2 (COVID-19) emergency.
Topics: Antiviral Agents; Chloroquine; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Ototoxicity; Pan | 2020 |