chloroquine has been researched along with Niemann-Pick Diseases in 1 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Niemann-Pick Diseases: A group of autosomal recessive disorders in which harmful quantities of lipids accumulate in the viscera and the central nervous system. They can be caused by deficiencies of enzyme activities (SPHINGOMYELIN PHOSPHODIESTERASE) or defects in intracellular transport, resulting in the accumulation of SPHINGOMYELINS and CHOLESTEROL. There are various subtypes based on their clinical and genetic differences.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levade, T | 1 |
| Vidal, F | 1 |
| Vermeersch, S | 1 |
| Andrieu, N | 1 |
| Gatt, S | 1 |
| Salvayre, R | 1 |
1 other study available for chloroquine and Niemann-Pick Diseases
| Article | Year |
|---|---|
Degradation of fluorescent and radiolabelled sphingomyelins in intact cells by a non-lysosomal pathway.
Topics: Bridged-Ring Compounds; Cell Line; Chloroquine; Dithiothreitol; Edetic Acid; Endocytosis; Fluorescen | 1995 |