chloroquine has been researched along with Neoplasms in 118 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is a kind of cytokine storm, which involves increased activity of TNF-α, IL-1, IL-6, and INF-γ." | 5.62 | Can chloroquine/hydroxychloroquine prove efficient in cancer cachexia? A hypothesis in the era of COVID-19. ( Czerw, A; Deptała, A; Kapala, P; Kiedrowska, M; Kiedrowski, M; Skoczynska, A, 2021) |
| " Chloroquine and hydroxychloroquine, with an original indication to prevent or cure malaria, have been successfully used to treat several infectious (HIV, Q fever, Whipple's disease, fungal infections), rheumatological (systemic lupus erythematosus, antiphospholipid antibody syndrome, rheumatoid arthritis, Sjögren's syndrome), and other immunological diseases." | 4.98 | Current and Future Use of Chloroquine and Hydroxychloroquine in Infectious, Immune, Neoplastic, and Neurological Diseases: A Mini-Review. ( Koudriavtseva, T; Plantone, D, 2018) |
| "Chloroquine (CHQ) is a cheap, relatively well tolerated drug initially developed for the treatment of malaria in the 1930s." | 4.84 | Chloroquine: novel uses & manifestations. ( Cooper, RG; Magwere, T, 2008) |
| "Epoxyazadiradione (1), a major compound derived from Neem oil, showed modest anti-plasmodial activity against CQ-resistant and CQ-sensitive strains of the most virulent human malaria parasite P." | 3.85 | Synthesis and evaluation of anti-plasmodial and cytotoxic activities of epoxyazadiradione derivatives. ( Allanki, AD; Ashok Yadav, P; Jain, N; Pavan Kumar, C; Sijwali, PS; Siva, B; Suresh Babu, K; Veerabhadra Rao, A, 2017) |
| "Serum-deprived U251 glioma, B16 melanoma and L929 fibrosarcoma cells were treated with chloroquine in vitro." | 3.78 | Chloroquine-mediated lysosomal dysfunction enhances the anticancer effect of nutrient deprivation. ( Arsikin, K; Bumbasirevic, V; Harhaji-Trajkovic, L; Janjetovic, K; Kravic-Stevovic, T; Pantovic, A; Petricevic, S; Ristic, B; Tovilovic, G; Trajkovic, V; Zogovic, N, 2012) |
| "We then emphasize how autophagy and cancer cells interacting with one another is a promising therapeutic target in cancer treatment." | 3.01 | Recent Update and Drug Target in Molecular and Pharmacological Insights into Autophagy Modulation in Cancer Treatment and Future Progress. ( Islam, M; Kim, B; Parvez, MAK; Rahman, MA; Rahman, MS; Saikat, ASM, 2023) |
| "Targeting tumors by regulating autophagy has become a therapeutic strategy of interest." | 2.82 | Repurposing drugs in autophagy for the treatment of cancer: From bench to bedside. ( Bu, F; Liu, J; Ouyang, L; Shuai, W; Sun, Q; Zhang, J, 2022) |
| "While not approved for cancer therapy, there are ongoing clinical trials to evaluate their safety and efficacy." | 2.82 | Autophagy Agents in Clinical Trials for Cancer Therapy: A Brief Review. ( Al-Zeidaneen, SA; Algwaiz, GF; Karim, NA; Mohsen, S; Nasef, N; Sobash, PT, 2022) |
| "Given that CQ loses its anticancer activity in acidic and hypoxic environment within a tumor, novel CQ analogs and/or their formulations are under active investigation to improve their physicochemical properties and biological activity." | 2.72 | Repurposing Chloroquine Analogs as an Adjuvant Cancer Therapy. ( Fong, W; To, KKW, 2021) |
| "However, the link between some anticancer mechanisms, clinical efficacy and pharmacological safety has not yet been fully defined." | 2.72 | Chloroquine and hydroxychloroquine in antitumor therapies based on autophagy-related mechanisms. ( Bezerra, DP; Ferreira, JRO; Ferreira, PMP; Militão, GCG; Sousa, RWR, 2021) |
| "A number of anticancer drugs with 4-aminoquinazoline core are in the market, e." | 2.61 | Recent advancements of 4-aminoquinazoline derivatives as kinase inhibitors and their applications in medicinal chemistry. ( Das, D; Hong, J, 2019) |
| "Malaria and cancer are chronic diseases." | 2.61 | Ferrocene-Based Compounds with Antimalaria/Anticancer Activity. ( Aderibigbe, BA; Peter, S, 2019) |
| "Clinically approved cancer therapies include small molecules, antibodies, and nanoparticles." | 2.58 | Chloroquine and nanoparticle drug delivery: A promising combination. ( Busatto, S; Ferrari, M; Mody, K; Pelt, J; Thompson, EA; Wolfram, J, 2018) |
| "In the context of cancer, Chloroquine was found to have direct effects on different types of malignancies that could potentiate chemotherapies." | 2.53 | Time to use a dose of Chloroquine as an adjuvant to anti-cancer chemotherapies. ( Pascolo, S, 2016) |
| "Chloroquine has been shown to stabilize p53 and induce p53-dependent apoptosis or cell cycle arrest." | 2.52 | The utility of chloroquine in cancer therapy. ( Liao, Z; Xiao, HT; Zhang, LJ; Zhang, Y, 2015) |
| "Herein, we review the effects of anti-cancer agents that impact metabolism administered concurrently with autophagy inhibitors on immune cells and consider the implications for patient response to therapy." | 2.48 | Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity. ( Hughson, LR; Lum, JJ; Poon, VI; Schlie, K; Townsend, KN; Westerback, A, 2012) |
| "Autophagy has dual roles in cancer, acting as both a tumor suppressor by preventing the accumulation of damaged proteins and organelles and as a mechanism of cell survival that can promote the growth of established tumors." | 2.47 | The role of autophagy in cancer: therapeutic implications. ( Chee, CE; Huang, S; Sinicrope, FA; Yang, ZJ, 2011) |
| "Chloroquine (CQ), N'-(7-chloroquinolin-4-yl)-N,N-diethyl-pentane-1,4-diamine, is widely used as an effective and safe anti-malarial and anti-rheumatoid agent." | 2.45 | Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies. ( Lee, H; Solomon, VR, 2009) |
| "The sensitivity for lung cancer in 489 studies was 93 per cent." | 2.35 | Cancer diagnosis. The role of tumor-imaging radiopharmaceuticals. ( Silberstein, EB, 1976) |
| "It is a kind of cytokine storm, which involves increased activity of TNF-α, IL-1, IL-6, and INF-γ." | 1.62 | Can chloroquine/hydroxychloroquine prove efficient in cancer cachexia? A hypothesis in the era of COVID-19. ( Czerw, A; Deptała, A; Kapala, P; Kiedrowska, M; Kiedrowski, M; Skoczynska, A, 2021) |
| " In addition, CQ, Ku, and Rap in combination with RL2 decreased activity of lysosomal protease Cathepsin D." | 1.51 | Cytotoxic and Antitumor Activity of Lactaptin in Combination with Autophagy Inducers and Inhibitors. ( Bagamanshina, AV; Kähne, T; Kit, YY; Koval, OA; Kuligina, EV; Lavrik, IN; Nushtaeva, AA; Richter, M; Richter, VA; Starykovych, MO; Troitskaya, OS; Wohlfromm, F; Yunusova, AY, 2019) |
| "FQ enhances the anticancer activity of several chemotherapeutics suggesting its potential application as an adjuvant to existing anticancer therapy." | 1.46 | Ferroquine, the next generation antimalarial drug, has antitumor activity. ( Biot, C; Delcourt, P; Dewailly, E; Dubois, C; Gordienko, D; Kondratska, K; Kondratskyi, A; Lemière, S; Prevarskaya, N; Skryma, R; Slomianny, C; Toillon, RA; Vanden Abeele, F, 2017) |
| "Similar effects were confirmed in cancer cells bearing tumor-associated p53 mutations and in H1299 (p53 null) with overexpressed p53R175H and p53R273H mutant proteins." | 1.43 | Reactivation of mutant p53 by capsaicin, the major constituent of peppers. ( Cirone, M; D'Orazi, G; Garufi, A; Pistritto, G, 2016) |
| "We reported that cancer cells upregulate autophagy as a survival mechanism to acidic stress." | 1.40 | Acidic extracellular pH neutralizes the autophagy-inhibiting activity of chloroquine: implications for cancer therapies. ( Buoncervello, M; De Milito, A; Hägg-Olofsson, M; Linder, S; Pellegrini, P; Strambi, A; Zipoli, C, 2014) |
| "The EGFR high expressing cells and tumors investigated in this study are highly dependent on autophagy for growth and survival." | 1.39 | EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival. ( Bussink, J; Jutten, B; Keulers, TG; Rouschop, KM; Savelkouls, K; Schaaf, MB; Span, PN; Theys, J; Vooijs, MA, 2013) |
| "Chloroquine has demonstrated high affinity for aldehyde dehydrogenase 1A1 (ALDH1), an enzyme expressed in the highly tumorigenic CD133+ brain tumor initiating subpopulation." | 1.38 | Synthesis and preliminary evaluation of n.c.a. iodoquine: a novel radiotracer with high uptake in cells with high ALDH1 expression. ( Chin, BB; Dai, D; Greer, KL; Hjelemand, A; Lascola, C; McDougald, D; McLendon, R; Metzler, SD; Reiman, R; Rich, J; Song, H; Storms, R; Vaidyanathan, G, 2012) |
| "Like the natural IgM, the epithelial cancer cell-derived IgM recognized a series of microbial antigens, such as single-stranded DNA, double-stranded DNA, lipopolysaccharide, and the HEp-2 cell antigen." | 1.38 | Spontaneous production of immunoglobulin M in human epithelial cancer cells. ( Geng, L; Hu, F; Huang, J; Liao, Q; Ma, T; Qiu, X; Shao, W; Yin, CC; Zhang, L; Zhao, L; Zheng, J, 2012) |
| "Autophagy inhibition is a novel cancer therapeutic strategy in the early stages of clinical trial testing." | 1.37 | Targeting autophagy addiction in cancer. ( Kimmelman, AC; Mancias, JD, 2011) |
| "Glutamine metabolism is crucial for cancer cell growth via the generation of intermediate molecules in the tricarboxylic acid (TCA) cycle, antioxidants and ammonia." | 1.37 | Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy resistance. ( Flomenberg, N; Howell, A; Ko, YH; Lin, Z; Lisanti, MP; Martinez-Outschoorn, UE; Pestell, RG; Sotgia, F, 2011) |
| "In several human cancer cell lines, hypoxia increased transcription of the essential autophagy genes microtubule-associated protein 1 light chain 3beta (MAP1LC3B) and autophagy-related gene 5 (ATG5) through the transcription factors ATF4 and CHOP, respectively, which are regulated by PKR-like ER kinase (PERK, also known as EIF2AK3)." | 1.36 | The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. ( Bussink, J; Dubois, L; Keulers, T; Koritzinsky, M; Lambin, P; Landuyt, W; Mujcic, H; Niessen, H; Rouschop, KM; Savelkouls, K; van den Beucken, T; van der Kogel, AJ; Voncken, JW; Wouters, BG, 2010) |
| "Chloroquine is a lysosomotropic agent that has been reported to enhance in vitro cytotoxicity of basic anticancer drugs." | 1.36 | Triggering liposomal drug release with a lysosomotropic agent. ( Lee, RJ; Li, H; Wu, J; Xiong, S; Yu, B, 2010) |
| "On the other hand, cotreatment of cancer cells with cetuximab and the mTOR inhibitor rapamycin resulted in an Atg-dependent and lysosomal inhibition-sensitive death of cancer cells that show only growth inhibition or weak apoptosis after cetuximab treatment, indicating that cell death may be achieved by activating the autophagy pathway in these cells." | 1.36 | Roles of autophagy in cetuximab-mediated cancer therapy against EGFR. ( Fan, Z; Li, X; Lu, Y; Pan, T, 2010) |
| "Thus, CQ is a very effective and cancer-specific chemosensitizer when used in combination with Akt inhibitors." | 1.35 | The efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquine. ( Hu, C; Lee, H; Solomon, VR; Ulibarri, G, 2008) |
| "Conversely, established tumors appear to utilize autophagy in order to survive periods of metabolic or hypoxic stress." | 1.35 | ARF, autophagy and tumor suppression. ( Murphy, ME; Pimkina, J, 2009) |
| "Tamoxifen is a known structural-mimic of cholesterol, which were both found to be similarly effective in preventing drug release from liposomes." | 1.29 | Tamoxifen decreases drug efflux from liposomes: relevance to its ability to reverse multidrug resistance in cancer cells? ( Kayyali, R; Marriott, C; Wiseman, H, 1994) |
| "Chloroquine phosphate pretreatment was employed prior to each antibody infusion to block receptor recycling and host-antigen processing." | 1.28 | Human-human monoclonal antibody directed against tumor surface antigen in the treatment of human malignancy. A pilot study. ( Alonso, K, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (22.03) | 18.7374 |
| 1990's | 7 (5.93) | 18.2507 |
| 2000's | 9 (7.63) | 29.6817 |
| 2010's | 54 (45.76) | 24.3611 |
| 2020's | 22 (18.64) | 2.80 |
| Authors | Studies |
|---|---|
| Amewu, RK | 1 |
| Chadwick, J | 1 |
| Hussain, A | 1 |
| Panda, S | 1 |
| Rinki, R | 1 |
| Janneh, O | 1 |
| Ward, SA | 1 |
| Miguel, C | 1 |
| Burrell-Saward, H | 1 |
| Vivas, L | 1 |
| O'Neill, PM | 1 |
| Srivastava, V | 1 |
| Lee, H | 3 |
| Ashok Yadav, P | 1 |
| Pavan Kumar, C | 1 |
| Siva, B | 1 |
| Suresh Babu, K | 1 |
| Allanki, AD | 1 |
| Sijwali, PS | 1 |
| Jain, N | 1 |
| Veerabhadra Rao, A | 1 |
| See, CS | 1 |
| Kitagawa, M | 1 |
| Liao, PJ | 1 |
| Lee, KH | 1 |
| Wong, J | 2 |
| Lee, SH | 1 |
| Dymock, BW | 1 |
| Chu, XM | 1 |
| Wang, C | 5 |
| Liu, W | 1 |
| Liang, LL | 1 |
| Gong, KK | 1 |
| Zhao, CY | 1 |
| Sun, KL | 1 |
| Das, D | 1 |
| Hong, J | 1 |
| Dou, X | 1 |
| Sun, X | 2 |
| Huang, H | 2 |
| Jiang, L | 1 |
| Jin, Z | 1 |
| Liu, Y | 5 |
| Zou, Y | 2 |
| Li, Z | 3 |
| Zhu, G | 1 |
| Jin, H | 2 |
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| Liu, Z | 3 |
| Bu, F | 1 |
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| Shuai, W | 1 |
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| Ouyang, L | 1 |
| Mohsen, S | 1 |
| Sobash, PT | 1 |
| Algwaiz, GF | 1 |
| Nasef, N | 1 |
| Al-Zeidaneen, SA | 1 |
| Karim, NA | 1 |
| Li, F | 2 |
| Chen, T | 1 |
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| Zhang, Y | 7 |
| Song, D | 1 |
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| Lin, XH | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Proflaxis for Healthcare Professionals Using Hydroxychloroquine Plus Vitamin Combining Vitamins C, D and Zinc During COVID-19 Pandemia: An Observational Study[NCT04326725] | 80 participants (Anticipated) | Observational | 2020-03-20 | Active, not recruiting | |||
| A Phase II Randomized Controlled Trial for the Addition of Chloroquine, an Autophagy Inhibitor, to Concurrent Chemoradiation for Newly Diagnosed Glioblastoma[NCT02432417] | Phase 2 | 0 participants (Actual) | Interventional | 2023-11-10 | Withdrawn (stopped due to The study was withdrawn due to a lack of funding. The researchers were unable to secure the necessary financial support to continue and complete the trial.) | ||
| A Phase I Trial for the Addition of Chloroquine, an Autophagy Inhibitor, to Concurrent Chemoradiation for Newly Diagnosed Glioblastoma[NCT02378532] | Phase 1 | 13 participants (Actual) | Interventional | 2016-08-31 | Completed | ||
| Phase 2 Study of Hydroxychloroquine to Increase Tumor Suppressor PAR-4 Levels in Oligometastatic Prostate Cancer[NCT04011410] | Phase 2 | 20 participants (Actual) | Interventional | 2019-12-03 | Active, not recruiting | ||
| Identification of Novel Autophagy Markers in Bladder Cancer Patients[NCT03254888] | 150 participants (Anticipated) | Observational | 2020-12-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
36 reviews available for chloroquine and Neoplasms
| Article | Year |
|---|---|
Quinoline and quinolone dimers and their biological activities: An overview.
Topics: Anti-Bacterial Agents; Antimalarials; Antineoplastic Agents; Bacteria; Dimerization; Humans; Neoplas | 2019 |
Recent advancements of 4-aminoquinazoline derivatives as kinase inhibitors and their applications in medicinal chemistry.
Topics: Animals; Antineoplastic Agents; Chemistry Techniques, Synthetic; Humans; Neoplasms; Protein Kinase I | 2019 |
Repurposing drugs in autophagy for the treatment of cancer: From bench to bedside.
Topics: Antineoplastic Agents; Autophagy; Chloroquine; Drug Repositioning; Humans; Neoplasms | 2022 |
Autophagy Agents in Clinical Trials for Cancer Therapy: A Brief Review.
Topics: Autophagy; Chloroquine; Humans; Hydroxychloroquine; Neoplasms; United States | 2022 |
Recent Update and Drug Target in Molecular and Pharmacological Insights into Autophagy Modulation in Cancer Treatment and Future Progress.
Topics: Antineoplastic Agents; Autophagy; Chloroquine; Humans; Hydroxychloroquine; Neoplasms | 2023 |
Ferrocene-Based Compounds with Antimalaria/Anticancer Activity.
Topics: Aminoquinolines; Antimalarials; Antineoplastic Agents; Chloroquine; Drug Resistance, Neoplasm; Drug | 2019 |
Dissecting pharmacological effects of chloroquine in cancer treatment: interference with inflammatory signaling pathways.
Topics: Animals; Antineoplastic Agents; Autophagy; Chloroquine; Humans; Inflammation Mediators; Neoplasms; N | 2020 |
Crosstalk between autophagy and apoptosis: Mechanisms and therapeutic implications.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Relat | 2020 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Repurposing Chloroquine Analogs as an Adjuvant Cancer Therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Chemotherapy, Adjuvant; Chloroquine; Drug Repo | 2021 |
Chloroquine and hydroxychloroquine in antitumor therapies based on autophagy-related mechanisms.
Topics: Antineoplastic Agents; Autophagy; Chloroquine; Clinical Trials as Topic; Drug Resistance, Neoplasm; | 2021 |
Targeting autophagy in cancer.
Topics: Animals; Antineoplastic Agents; Autophagy; Biomarkers, Tumor; Chloroquine; Clinical Trials as Topic; | 2017 |
Current and Future Use of Chloroquine and Hydroxychloroquine in Infectious, Immune, Neoplastic, and Neurological Diseases: A Mini-Review.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antimalarials; Antineoplastic Agents; Antirheumatic | 2018 |
Chloroquine and nanoparticle drug delivery: A promising combination.
Topics: Animals; Antimalarials; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Chloroquine; Drug | 2018 |
Autophagy therapeutics: preclinical basis and initial clinical studies.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Survival; Chloroquine; Clin | 2018 |
The clinical value of using chloroquine or hydroxychloroquine as autophagy inhibitors in the treatment of cancers: A systematic review and meta-analysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Autophagy; Chloroquine; Clinical Trials as Topic; Da | 2018 |
New use for old drugs? Prospective targets of chloroquines in cancer therapy.
Topics: Animals; Antimalarials; Chloroquine; Clinical Trials as Topic; Humans; Neoplasms; Neoplastic Stem Ce | 2014 |
The utility of chloroquine in cancer therapy.
Topics: Antimalarials; Antineoplastic Agents; Apoptosis; Autophagy; Chloroquine; Humans; Neoplasms | 2015 |
Time to use a dose of Chloroquine as an adjuvant to anti-cancer chemotherapies.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chloroquine; Humans; Neoplasms; Neopla | 2016 |
To live or let die: Unclear task of autophagy in the radiosensitization battle.
Topics: Ataxia Telangiectasia Mutated Proteins; Autophagy; Cell Hypoxia; Chloroquine; Humans; Membrane Prote | 2016 |
Chloroquine: novel uses & manifestations.
Topics: Antimalarials; Chloroquine; Humans; Malaria; Neoplasms; Virus Diseases | 2008 |
[Metalloproteinases. Structure and function].
Topics: 4-Aminobenzoic Acid; Animals; Apoptosis; Arthritis; Autoimmune Diseases; Cell Movement; Chloroquine; | 2008 |
Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Chloroquine; Drug Syn | 2009 |
Novel proteasome inhibitors to overcome bortezomib resistance.
Topics: Allosteric Site; Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tu | 2011 |
The role of autophagy in cancer: therapeutic implications.
Topics: Animals; Antineoplastic Agents; Autophagy; Chloroquine; Gene Expression Regulation, Neoplastic; Huma | 2011 |
Molecular crosstalk between the proteasome, aggresomes and autophagy: translational potential and clinical implications.
Topics: Adenine; Antineoplastic Agents; Autophagy; Boronic Acids; Bortezomib; Chloroquine; Clinical Trials a | 2012 |
Targeting autophagic pathways for cancer drug discovery.
Topics: Antibiotics, Antineoplastic; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Chloroquine; Drug D | 2013 |
Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoc | 2012 |
Tumor cell autophagy as an adaptive response mediating resistance to treatments such as antiangiogenic therapy.
Topics: Adaptation, Biological; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Autophagy; Chloroqu | 2012 |
Chloroquine in cancer therapy: a double-edged sword of autophagy.
Topics: Animals; Antineoplastic Agents; Autophagy; Chloroquine; Humans; Kidney; Neoplasms | 2013 |
Immunoliposomes in vivo.
Topics: Amphotericin B; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Biological Availability; Can | 1994 |
Cancer diagnosis. The role of tumor-imaging radiopharmaceuticals.
Topics: Antibodies, Neoplasm; Bismuth; Bleomycin; Carcinoembryonic Antigen; Cesium Radioisotopes; Chelating | 1976 |
Similarities and differences between the multidrug resistance phenotype of mammalian tumor cells and chloroquine resistance in Plasmodium falciparum.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloroquine; Drug Resistance; Gene | 1991 |
Enhancement of the antimalarial effect of chloroquine on drug-resistant parasite strains--a critical examination of the reversal of multidrug resistance.
Topics: Animals; Antineoplastic Agents; Chloroquine; Drug Resistance; Gene Amplification; Genes; Humans; Neo | 1991 |
[Clinical picture, diagnostics and therapy of amyloidoses].
Topics: Adrenal Gland Diseases; Amyloidosis; Biopsy; Chloroquine; Chronic Disease; Gastrointestinal Diseases | 1972 |
Multiple combination therapy in cancer chemotherapy in Japan.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chloroquine; Cyclophosphamide; Cytarabine; Drug | 1969 |
1 trial available for chloroquine and Neoplasms
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
82 other studies available for chloroquine and Neoplasms
| Article | Year |
|---|---|
Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers.
Topics: Antimalarials; Antineoplastic Agents; Caspase 3; Cell Line, Tumor; Dimerization; Humans; Malaria, Fa | 2013 |
Synthesis and bio-evaluation of novel quinolino-stilbene derivatives as potential anticancer agents.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Drug Screening Assays, Antitumor; Hu | 2015 |
Synthesis and evaluation of anti-plasmodial and cytotoxic activities of epoxyazadiradione derivatives.
Topics: Animals; Antimalarials; Antineoplastic Agents; Azadirachta; Cell Line, Tumor; Cell Proliferation; Hu | 2017 |
Discovery of the cancer cell selective dual acting anti-cancer agent (Z)-2-(1H-indol-3-yl)-3-(isoquinolin-5-yl)acrylonitrile (A131).
Topics: Acrylonitrile; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplas | 2018 |
Discovery of novel ataxia telangiectasia mutated (ATM) kinase modulators: Computational simulation, biological evaluation and cancer combinational chemotherapy study.
Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor | 2022 |
Enhanced Cancer Starvation Therapy Enabled by an Autophagy Inhibitors-Encapsulated Biomimetic ZIF-8 Nanodrug: Disrupting and Harnessing Dual Pro-Survival Autophagic Responses.
Topics: Autophagy; Biomimetics; Cell Line, Tumor; Chloroquine; Glucose Oxidase; Nanoparticles; Neoplasms; Ze | 2022 |
Autophagy responsive intra-intercellular delivery nanoparticles for effective deep solid tumor penetration.
Topics: Autophagy; Cell Line, Tumor; Chloroquine; Docetaxel; Drug Delivery Systems; Humans; Nanoparticles; N | 2022 |
Lysosomal lipid peroxidation mediates immunogenic cell death.
Topics: Chloroquine; Humans; Hydroxychloroquine; Immunogenic Cell Death; Lipid Peroxidation; Lysosomes; Neop | 2023 |
Hollow Cu
Topics: Autophagy; Cell Line, Tumor; Chloroquine; Combined Modality Therapy; Humans; Nanoparticles; Nanostru | 2023 |
Hyaluronan nanogel co-loaded with chloroquine to enhance intracellular cisplatin delivery through lysosomal permeabilization and lysophagy inhibition.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chloroquine; Cisplatin; Humans; Hyaluronic Acid; Lysosomes; | 2024 |
Exosomes as a Surrogate Marker for Autophagy in Peripheral Blood, Correlative Data from Phase I Study of Chloroquine in Combination with Carboplatin/Gemcitabine in Advanced Solid Tumors.
Topics: Antimalarials; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Biomarkers; Car | 2019 |
A Metal-Organic Framework (MOF) Fenton Nanoagent-Enabled Nanocatalytic Cancer Therapy in Synergy with Autophagy Inhibition.
Topics: Animals; Apoptosis; Autophagy; Catalysis; Cell Line, Tumor; Chloroquine; Drug Synergism; Female; Hum | 2020 |
Complementary autophagy inhibition and glucose metabolism with rattle-structured polydopamine@mesoporous silica nanoparticles for augmented low-temperature photothermal therapy and
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line, Tumor; Chloroquine; D | 2020 |
Can chloroquine/hydroxychloroquine prove efficient in cancer cachexia? A hypothesis in the era of COVID-19.
Topics: Autophagy; Cachexia; Chloroquine; COVID-19 Drug Treatment; Cytokine Release Syndrome; Cytokines; Hum | 2021 |
6-Azauridine Induces Autophagy-Mediated Cell Death via a p53- and AMPK-Dependent Pathway.
Topics: AMP-Activated Protein Kinase Kinases; Antineoplastic Agents; Apoptosis; Autophagic Cell Death; Autop | 2021 |
Binding of hydroxychloroquine and chloroquine dimers to palmitoyl-protein thioesterase 1 (PPT1) and its glycosylated forms: a computational approach.
Topics: Asparagine; Child; Chloroquine; Fatty Acids; Humans; Hydroxychloroquine; Membrane Proteins; Neoplasm | 2022 |
Therapeutic Approach of KRAS Mutant Tumours by the Combination of Pharmacologic Ascorbate and Chloroquine.
Topics: Antineoplastic Agents; Autophagy; Chloroquine; Models, Theoretical; Neoplasms; Proto-Oncogene Protei | 2021 |
Co-Delivery of Doxorubicin and Chloroquine by Polyglycerol Functionalized MoS2 Nanosheets for Efficient Multidrug-Resistant Cancer Therapy.
Topics: Chloroquine; Disulfides; Doxorubicin; Drug Resistance, Neoplasm; Glycerol; HeLa Cells; Humans; Micro | 2021 |
Micelle nanovehicles for co-delivery of Lepidium meyenii Walp. (maca) polysaccharide and chloroquine to tumor-associated macrophages for synergistic cancer immunotherapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Polarity; Chloroquine; Female; Immunotherapy; | 2021 |
Verapamil treatment induces cytoprotective autophagy by modulating cellular metabolism.
Topics: Antimalarials; Antineoplastic Agents; Autophagosomes; Autophagy; Autophagy-Related Protein 5; Autoph | 2017 |
Autophagy inhibition enabled efficient photothermal therapy at a mild temperature.
Topics: Animals; Autophagy; Cell Line, Tumor; Chloroquine; Drug Carriers; HeLa Cells; Humans; Hyperthermia, | 2017 |
mAb MDR1-modified chitosan nanoparticles overcome acquired EGFR-TKI resistance through two potential therapeutic targets modulation of MDR1 and autophagy.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member | 2017 |
Ferroquine, the next generation antimalarial drug, has antitumor activity.
Topics: Aminoquinolines; Animals; Antimalarials; Antineoplastic Agents; Autophagy; Caspases; Cell Cycle Chec | 2017 |
Accelerated lipid catabolism and autophagy are cancer survival mechanisms under inhibited glutaminolysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Benzophenanthridines; Cell Lin | 2018 |
The release and activity of HMGB1 in ferroptosis.
Topics: Animals; Autophagy; Carbolines; Cell Death; Cell Line, Tumor; Chloroquine; Ferritins; Fibroblasts; H | 2019 |
Supramolecular self-assembly of triazine-based small molecules: targeting the endoplasmic reticulum in cancer cells.
Topics: Chloroquine; Drug Delivery Systems; Endoplasmic Reticulum; Fluorouracil; HeLa Cells; Humans; Neoplas | 2019 |
Chloroquine Urea Derivatives: Synthesis and Antitumor Activity in Vitro.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chloroquine; Drug Design; Drug Screenin | 2018 |
Cytotoxic and Antitumor Activity of Lactaptin in Combination with Autophagy Inducers and Inhibitors.
Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Caseins; Cathepsin D; Cell Death; Cel | 2019 |
Antimalarial activity of axidjiferosides, new β-galactosylceramides from the African sponge Axinyssa djiferi.
Topics: Animals; Antimalarials; Cell Line, Tumor; Ceramides; Chloroquine; Drug Resistance; Female; Galactosy | 2013 |
Cytoprotective and nonprotective autophagy in cancer therapy.
Topics: Animals; Autophagy; Cell Line, Tumor; Chloroquine; Cytoprotection; Disease Models, Animal; Humans; N | 2013 |
EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival.
Topics: Animals; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; ErbB Receptors | 2013 |
EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival.
Topics: Animals; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; ErbB Receptors | 2013 |
EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival.
Topics: Animals; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; ErbB Receptors | 2013 |
EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival.
Topics: Animals; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; ErbB Receptors | 2013 |
Single cell metabolic profiling of tumor mimics.
Topics: Chloroquine; Flow Cytometry; Glycosphingolipids; Humans; Metabolome; Neoplasms; Principal Component | 2013 |
Acidic extracellular pH neutralizes the autophagy-inhibiting activity of chloroquine: implications for cancer therapies.
Topics: Acids; Apoptosis; Autophagy; Cell Line, Tumor; Chloroquine; Extracellular Space; Humans; Hydrogen-Io | 2014 |
How to teach an old dog new tricks: autophagy-independent action of chloroquine on the tumor vasculature.
Topics: Animals; Antimalarials; Autophagy; Chloroquine; Endosomes; Gene Deletion; Humans; Hypoxia; Mice; Neo | 2014 |
Simultaneous activation and inhibition of autophagy sensitizes cancer cells to chemotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Cell Line, Tumor; Cel | 2016 |
Reactivation of mutant p53 by capsaicin, the major constituent of peppers.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Capsaicin; Capsicum; Cell Line, Tumor; Cell P | 2016 |
Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chloroquine; Humans; Mice; Neoplasm Metast | 2017 |
Modification of tumour cell metabolism modulates sensitivity to Chk1 inhibitor-induced DNA damage.
Topics: Aminoquinolines; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Chloroquine; | 2017 |
The efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquine.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cell Line, Tumor; Cell Proliferation | 2008 |
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents.
Topics: Animals; Apoptosis; Autophagy; Autophagy-Related Protein 7; Benzylamines; Cell Cycle; Cell Line, Tum | 2008 |
Chloroquine (SN-7618) pathologic changes observed in rats which for 2 years had been fed various proportions.
Topics: Animals; Chloroquine; Neoplasms; Rats; Thyroid Gland; Thyroid Neoplasms | 1948 |
ARF, autophagy and tumor suppression.
Topics: ADP-Ribosylation Factor 1; Animals; Antineoplastic Agents; Autophagy; Chloroquine; Gene Silencing; G | 2009 |
A role for p53 in the regulation of extracellular matrix metalloproteinase inducer in human cancer cells.
Topics: Basigin; Blotting, Western; Cell Line, Tumor; Cell Movement; Chloroquine; Down-Regulation; Enzyme-Li | 2009 |
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Topics: Activating Transcription Factor 4; Animals; Autophagy; Autophagy-Related Protein 5; Cell Hypoxia; Ce | 2010 |
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Topics: Activating Transcription Factor 4; Animals; Autophagy; Autophagy-Related Protein 5; Cell Hypoxia; Ce | 2010 |
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Topics: Activating Transcription Factor 4; Animals; Autophagy; Autophagy-Related Protein 5; Cell Hypoxia; Ce | 2010 |
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Topics: Activating Transcription Factor 4; Animals; Autophagy; Autophagy-Related Protein 5; Cell Hypoxia; Ce | 2010 |
Disruption of lysosome function promotes tumor growth and metastasis in Drosophila.
Topics: Animals; Chloroquine; Crosses, Genetic; Drosophila; Genotype; Green Fluorescent Proteins; Humans; Ly | 2010 |
Triggering liposomal drug release with a lysosomotropic agent.
Topics: Animals; Antibiotics, Antineoplastic; Arylsulfonates; Cell Line, Tumor; Chloroquine; Daunorubicin; F | 2010 |
Roles of autophagy in cetuximab-mediated cancer therapy against EGFR.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Apoptosis; Autophagy; Cell Line, Tumor; C | 2010 |
Identification of aneuploidy-selective antiproliferation compounds.
Topics: Aminoimidazole Carboxamide; Aneuploidy; Animals; Antineoplastic Agents; Apoptosis; Benzoquinones; Ce | 2011 |
Synthesis and preliminary evaluation of n.c.a. iodoquine: a novel radiotracer with high uptake in cells with high ALDH1 expression.
Topics: Aldehyde Dehydrogenase 1 Family; Animals; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Chlo | 2012 |
Autophagy inhibition enhances daunorubicin-induced apoptosis in K562 cells.
Topics: Antibiotics, Antineoplastic; Antirheumatic Agents; Apoptosis; Autophagy; Chloroquine; Daunorubicin; | 2011 |
Targeting autophagy addiction in cancer.
Topics: Animals; Antineoplastic Agents; Autophagy; Chloroquine; Genes, ras; Humans; Hydroxychloroquine; Mice | 2011 |
Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy resistance.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Caveolin 1; Cell Communication; Cell Line, Tumo | 2011 |
Chloroquine-mediated lysosomal dysfunction enhances the anticancer effect of nutrient deprivation.
Topics: Animals; Antimalarials; Caloric Restriction; Cell Death; Cell Line, Tumor; Cell Survival; Chloroquin | 2012 |
Spontaneous production of immunoglobulin M in human epithelial cancer cells.
Topics: Antibodies, Neoplasm; Autoantigens; B-Lymphocytes; Cell Line, Tumor; Chloroquine; Epithelial Cells; | 2012 |
BASIC AND CLINICAL STUDIES ON THE TREATMENT OF MALIGNANT TUMORS WITH A FIBROBLAST-INHIBITING AGENT, CHLOROQUINE.
Topics: Animals; Biomedical Research; Carcinoma, Brown-Pearce; Carcinoma, Ehrlich Tumor; Chloroquine; Fibrob | 1963 |
THE DESTRUCTIVE FORCE OF SUNLIGHT.
Topics: 4-Aminobenzoic Acid; Aminobenzoates; Antimalarials; Chloroquine; Dermatology; Humans; Neoplasms; Pho | 1964 |
STUDIES ON THE TREATMENT OF MALIGNANT TUMORS WITH FIBROBLAST-INHIBITING AGENT. II. EFFECTS OF CHLOROQUINE ON ANIMAL TUMORS.
Topics: Animals; Antineoplastic Agents; Carcinoma, Brown-Pearce; Carcinoma, Ehrlich Tumor; Chloroquine; Fibr | 1963 |
STUDIES ON THE TREATMENT OF MALIGNANT TUMORS WITH FIBROBLAST-INHIBITING AGENT. I. FIBROBLAST-INHIBITING ACTION OF CHLOROQUINE.
Topics: Antineoplastic Agents; Chick Embryo; Chloroquine; Chondroitin; Connective Tissue; Fibroblasts; Granu | 1963 |
STUDIES ON THE TREATMENT OF MALIGNANT TUMORS WITH FIBROBLAST-INHIBITING AGENT. 3. EFFECTS OF CHLOROQUINE ON HUMAN CANCERS.
Topics: Chloroquine; Drug Therapy; Fibroblasts; Geriatrics; Lung Neoplasms; Neoplasms; Radiography; Radiogra | 1964 |
STUDIES ON THE TREATMENT OF MALIGNANT TUMORS WITH FIBROBLAST-INHIBITING AGENT. IV. EFFECTS OF CHLOROQUINE ON MALIGNANT LYMPHOMAS.
Topics: Chloroquine; Fibroblasts; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Lymphocytes; Lympho | 1964 |
A PROBLEM IN RESEARCH.
Topics: Antineoplastic Agents; Chloroquine; Electron Transport Complex IV; Mice; Neoplasms; Neoplasms, Exper | 1965 |
SOME CHEMICAL INFLUENCES ON HAIR GROWTH AND PIGMENTATION.
Topics: Alopecia; Aminopterin; Anticoagulants; Child; Chloroquine; Colchicine; Cyclophosphamide; Geriatrics; | 1965 |
[CUTANEOUS LYMPHOCYTOMAS].
Topics: Chloroquine; Humans; Lymphoma; Methylprednisolone; Neoplasms; Pathology; Pseudolymphoma; Skin Neopla | 1965 |
Experimental chemotherapy studies. II. The reactions of chloroquine mustard (CQM) and nitrogen mustard (HN2) with Ehrlich cells.
Topics: Chloroquine; Mechlorethamine; Mustard Plant; Neoplasms; Nitrogen Mustard Compounds | 1961 |
Autophagy: is it cancer's friend or foe?
Topics: Animals; Antineoplastic Agents; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Survival; C | 2006 |
[Studies on the treatment of malignant tumor with fibroblast-inhibiting agents].
Topics: Aged; Animals; Antineoplastic Agents; Chloroquine; Female; Fibroblasts; Humans; Male; Mice; Middle A | 1966 |
Delivery of ricin and abrin A-chains to human carcinoma cells in culture following covalent linkage to monoclonal antibody LICR-LOND-Fib 75.
Topics: Abrin; Animals; Antibodies, Monoclonal; Cells, Cultured; Chloroquine; Humans; Neoplasms; Plant Prote | 1984 |
An overview of benefit/risk of disease modifying treatment of rheumatoid arthritis as of today.
Topics: Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyclophosphamide; Female; Gold; Humans; Hydroxychl | 1982 |
Tamoxifen decreases drug efflux from liposomes: relevance to its ability to reverse multidrug resistance in cancer cells?
Topics: Antineoplastic Agents; Chloroquine; Cholesterol; Drug Resistance; Humans; Kinetics; Liposomes; Membr | 1994 |
Modulation of the function of human MDR1 P-glycoprotein by the antimalarial drug mefloquine.
Topics: Affinity Labels; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sit | 1996 |
4-[3-(2-Nitro-1-imidazolyl)propylamino]-7-chloroquinoline hydrochloride (NLCQ-1), a novel bioreductive compound as a hypoxia-selective cytotoxin.
Topics: Aminoquinolines; Animals; Antineoplastic Agents; Cell Survival; Chloroquine; Chromatography, Thin La | 2000 |
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; | 1977 |
Human-human monoclonal antibody directed against tumor surface antigen in the treatment of human malignancy. A pilot study.
Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Neoplasm; Chloroqui | 1991 |
Public-health epidemiology in Vanuatu.
Topics: Adolescent; Anemia; Animals; Cardiovascular Diseases; Child; Child, Preschool; Chloroquine; Drug Res | 1990 |
Transport proteins. Export-import family expands.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloroquine; Drug Resistance; Huma | 1989 |
Myopathies associated with systemic diseases.
Topics: Alcoholism; Anti-Bacterial Agents; Chloroquine; Collagen Diseases; Endocrine System Diseases; Erythe | 1971 |
[On the value of chloroquine in the treatment of malignant tumor diseases].
Topics: Adenocarcinoma, Scirrhous; Adult; Aged; Animals; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, E | 1967 |
Amebic liver abscess following metronidazole therapy for amebic colitis.
Topics: Adult; Chloroquine; Dysentery, Amebic; Emetine; Entamoeba histolytica; Follow-Up Studies; Heart Dise | 1974 |
Myopathy.
Topics: Alcoholism; Chloroquine; Glucosyltransferases; Glycogen Storage Disease; Humans; Ischemia; Muscular | 1970 |
[Multiple drug therapy of malignant tumor using fibroblast-suppresive agents as the basis].
Topics: Aged; Antineoplastic Agents; Chloroquine; Drug Synergism; Female; Fibroblasts; Humans; Male; Neoplas | 1970 |
[Cytostatic effect of resochin and atebrin (compare same journal 20 (N.F.) 28: 1591 (1969))].
Topics: Animals; Antineoplastic Agents; Chloroquine; Humans; Neoplasms; Neoplasms, Experimental; Quinacrine | 1970 |
Early cellular inflammation and neoplasia control.
Topics: Arsenic; Carcinogens; Chloroquine; Folliculitis; Infections; Inflammation; Neoplasms; Psoriasis; Ski | 1968 |