chloroquine has been researched along with Neoplasms, Nerve Sheath in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Combined chloroquine and HDACi treatment abrogates growth of human MPNST xenografts and lung metastases." | 3.77 | Autophagy blockade enhances HDAC inhibitors' pro-apoptotic effects: potential implications for the treatment of a therapeutic-resistant malignancy. ( Lev, D; Lopez, G; Torres, K, 2011) |
| "Malignant peripheral nerve sheath tumors (MPNSTs) are rapidly progressive Schwann cell neoplasms." | 1.38 | The pan erbB inhibitor PD168393 enhances lysosomal dysfunction-induced apoptotic death in malignant peripheral nerve sheath tumor cells. ( Byer, S; Carroll, SL; Kaza, N; Kohli, L; Lavalley, NJ; Roth, KA; Turner, KL, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lopez, G | 1 |
| Torres, K | 1 |
| Lev, D | 1 |
| Kohli, L | 1 |
| Kaza, N | 1 |
| Lavalley, NJ | 1 |
| Turner, KL | 1 |
| Byer, S | 1 |
| Carroll, SL | 1 |
| Roth, KA | 1 |
2 other studies available for chloroquine and Neoplasms, Nerve Sheath
| Article | Year |
|---|---|
Autophagy blockade enhances HDAC inhibitors' pro-apoptotic effects: potential implications for the treatment of a therapeutic-resistant malignancy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Chloroquine; Gene Expression Regulation, Neopl | 2011 |
The pan erbB inhibitor PD168393 enhances lysosomal dysfunction-induced apoptotic death in malignant peripheral nerve sheath tumor cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Caspases; Cell Line, Tumor; Ce | 2012 |