chloroquine has been researched along with Myocarditis in 11 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Myocarditis: Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In fact, two of the actually used drugs against SARS-CoV2, such as chloroquine and the combination lopinavir/ritonavir, might determine a QT (the time from the start of the Q wave to the end of the T wave) interval prolongation and they show several interactions with antiarrhythmic drugs and antipsychotic medications, making them prone to an increased risk of developing arrhythmias." | 5.12 | COVID-19 and the burning issue of drug interaction: never forget the ECG. ( Cameli, M; Cameli, P; Franchi, F; Mandoli, GE; Menci, D; Mondillo, S; Sciaccaluga, C; Sisti, N; Valente, S, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Sciaccaluga, C | 1 |
| Cameli, M | 1 |
| Menci, D | 1 |
| Mandoli, GE | 1 |
| Sisti, N | 1 |
| Cameli, P | 1 |
| Franchi, F | 1 |
| Mondillo, S | 1 |
| Valente, S | 1 |
| Ogah, OS | 1 |
| Umuerri, EM | 1 |
| Adebiyi, A | 1 |
| Orimolade, OA | 1 |
| Sani, MU | 1 |
| Ojji, DB | 1 |
| Mbakwem, AC | 1 |
| Stewart, S | 1 |
| Sliwa, K | 1 |
| Gantait, K | 1 |
| Gantait, I | 1 |
| Gorbea, C | 1 |
| Makar, KA | 1 |
| Pauschinger, M | 1 |
| Pratt, G | 1 |
| Bersola, JL | 1 |
| Varela, J | 1 |
| David, RM | 1 |
| Banks, L | 1 |
| Huang, CH | 1 |
| Li, H | 1 |
| Schultheiss, HP | 1 |
| Towbin, JA | 1 |
| Vallejo, JG | 1 |
| Bowles, NE | 1 |
| MOSORA, N | 1 |
| FEKETE, T | 1 |
| PAPILIAN, VV | 1 |
| SCHUETZ, E | 1 |
| FRENGER, W | 1 |
| Mono, G | 1 |
| Kuhn, E | 1 |
| Frame, JD | 1 |
| Baldwin, JM | 1 |
| Gocke, DJ | 1 |
| Troup, JM | 1 |
| Calabro, JJ | 1 |
| Katz, RM | 1 |
| Maltz, BA | 1 |
| Markowitz, SM | 1 |
| Martinez, AJ | 1 |
| Duma, RJ | 2 |
| Shiel, FO | 1 |
| Ferrell, HW | 1 |
| Nelson, EC | 1 |
| Jones, MM | 1 |
4 reviews available for chloroquine and Myocarditis
| Article | Year |
|---|---|
COVID-19 and the burning issue of drug interaction: never forget the ECG.
Topics: Adenosine Monophosphate; Alanine; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Antiviral | 2021 |
SARS-CoV 2 Infection (Covid-19) and Cardiovascular Disease in Africa: Health Care and Socio-Economic Implications.
Topics: Acute Coronary Syndrome; Africa; Antimalarials; Arrhythmias, Cardiac; Cardiovascular Diseases; Chlor | 2021 |
[Cardiotoxic effects of drugs and various other substances. A review].
Topics: Adrenergic Agonists; Amphetamine; Antimony; Arrhythmias, Cardiac; Arsenic Poisoning; Catecholamines; | 1978 |
A critical reappraisal of juvenile rheumatoid arthritis.
Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine | 1971 |
7 other studies available for chloroquine and Myocarditis
| Article | Year |
|---|---|
Vivax malaria complicated by myocarditis.
Topics: Adolescent; Anti-Inflammatory Agents; Antimalarials; Chloroquine; Dexamethasone; Humans; Malaria, Vi | 2013 |
A role for Toll-like receptor 3 variants in host susceptibility to enteroviral myocarditis and dilated cardiomyopathy.
Topics: Adult; Aged; Amino Acid Sequence; Animals; Autophagy; Base Sequence; Cardiomyopathy, Dilated; Cell L | 2010 |
[ON A CASE OF DERMATOMYOSITIS WITH MULTIPLE ORGANIC INVOLVEMENT].
Topics: Adolescent; Chloroquine; Cortisone; Dermatomyositis; Drug Therapy; Electrocardiography; Hepatitis; H | 1965 |
[LUPUS ERYTHEMATOSIS SYNDROME FOLLOWING PROLONGED HYDANTOIN THERAPY].
Topics: Adrenal Cortex Hormones; Arthritis; Arthritis, Rheumatoid; Chloroquine; Drug Therapy; Electrocardiog | 1965 |
Lassa fever, a new virus disease of man from West Africa. I. Clinical description and pathological findings.
Topics: Acute Disease; Adult; Aged; Autopsy; Back Pain; Blood; Blood Cell Count; Chloroquine; Edema; Female; | 1970 |
Myocarditis associated with primary amebic (Naegleria) meningoencephalitis.
Topics: Adolescent; Adult; Amoeba; Amphotericin B; Brain; Bronchopneumonia; Child; Chloroquine; Electrocardi | 1974 |
Primary amebic meningoencephalitis.
Topics: Adolescent; Amebiasis; Amoeba; Autopsy; Brain; Cerebrospinal Fluid; Chloroquine; Diagnosis, Differen | 1969 |