chloroquine has been researched along with Muscular Dystrophy, Duchenne in 1 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Muscular Dystrophy, Duchenne: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine treatment after gymnotic delivery helped increase nuclear AON levels." | 1.46 | Intracellular Distribution and Nuclear Activity of Antisense Oligonucleotides After Unassisted Uptake in Myoblasts and Differentiated Myotubes In Vitro. ( Aguilera, B; Croes, HJE; Datson, NA; de Visser, PC; González-Barriga, A; Kranzen, J; Mulders, SAM; Nillessen, B; van Deutekom, JCT; van Kessel, IDG; Wansink, DG; Wieringa, B, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-Barriga, A | 1 |
| Nillessen, B | 1 |
| Kranzen, J | 1 |
| van Kessel, IDG | 1 |
| Croes, HJE | 1 |
| Aguilera, B | 1 |
| de Visser, PC | 1 |
| Datson, NA | 1 |
| Mulders, SAM | 1 |
| van Deutekom, JCT | 1 |
| Wieringa, B | 1 |
| Wansink, DG | 1 |
1 other study available for chloroquine and Muscular Dystrophy, Duchenne
| Article | Year |
|---|---|
Intracellular Distribution and Nuclear Activity of Antisense Oligonucleotides After Unassisted Uptake in Myoblasts and Differentiated Myotubes In Vitro.
Topics: Analysis of Variance; Animals; Cell Differentiation; Cell Line; Cell Nucleus; Cell Proliferation; Ch | 2017 |