chloroquine has been researched along with Mouth Neoplasms in 10 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Mouth Neoplasms: Tumors or cancer of the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine, which is a widely used antimalarial drug, has been reported to exert anticancer activity in some tumor types; however, its potential effects on oral squamous cell carcinoma (OSCC) remain unclear." | 1.46 | In vitro and in vivo antitumor effects of chloroquine on oral squamous cell carcinoma. ( Cheng, B; Jia, L; Ling, J; Wang, J; Wu, J; Wu, T, 2017) |
| "Tetrandrine treatment induced the levels of LC-3 II, Atg-5, beclin-1, p-S6, p-ULK, p-mTOR, p-Akt (S473) and raptor." | 1.39 | Tetrandrine induces cell death in SAS human oral cancer cells through caspase activation-dependent apoptosis and LC3-I and LC3-II activation-dependent autophagy. ( Chang, SJ; Huang, AC; Lai, TY; Lien, JC; Lin, MW; Wu, PP; Yang, JS, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Campiani, G | 1 |
| Khan, T | 1 |
| Ulivieri, C | 1 |
| Staiano, L | 1 |
| Papulino, C | 1 |
| Magnano, S | 1 |
| Nathwani, S | 1 |
| Ramunno, A | 1 |
| Lucena-Agell, D | 1 |
| Relitti, N | 1 |
| Federico, S | 1 |
| Pozzetti, L | 1 |
| Carullo, G | 1 |
| Casagni, A | 1 |
| Brogi, S | 1 |
| Vanni, F | 1 |
| Galatello, P | 1 |
| Ghanim, M | 1 |
| McCabe, N | 1 |
| Lamponi, S | 1 |
| Valoti, M | 1 |
| Ibrahim, O | 1 |
| O'Sullivan, J | 1 |
| Turkington, R | 1 |
| Kelly, VP | 1 |
| VanWemmel, R | 1 |
| Díaz, JF | 1 |
| Gemma, S | 1 |
| Zisterer, D | 1 |
| Altucci, L | 1 |
| De Matteis, A | 1 |
| Butini, S | 1 |
| Benedetti, R | 1 |
| Li, Q | 1 |
| Liu, X | 1 |
| Yan, W | 1 |
| Chen, Y | 1 |
| Jia, L | 1 |
| Wang, J | 1 |
| Wu, T | 1 |
| Wu, J | 1 |
| Ling, J | 1 |
| Cheng, B | 1 |
| Huang, AC | 1 |
| Lien, JC | 1 |
| Lin, MW | 1 |
| Yang, JS | 1 |
| Wu, PP | 1 |
| Chang, SJ | 1 |
| Lai, TY | 1 |
| Yen, CY | 1 |
| Chiang, WF | 1 |
| Liu, SY | 1 |
| Cheng, PC | 1 |
| Lee, SY | 1 |
| Hong, WZ | 1 |
| Lin, PY | 1 |
| Lin, MH | 1 |
| Liu, YC | 1 |
| Bai, LY | 1 |
| Weng, JR | 1 |
| Hu, JL | 1 |
| Wang, D | 1 |
| Sargeant, AM | 1 |
| Chiu, CF | 1 |
| Quan, HY | 2 |
| Zhou, LJ | 1 |
| Li, AD | 1 |
| Zhang, ZB | 1 |
| Seth, P | 2 |
| Fitzgerald, DJ | 1 |
| Willingham, MC | 2 |
| Pastan, I | 2 |
| Schmidt, CR | 1 |
| Tiede, D | 1 |
10 other studies available for chloroquine and Mouth Neoplasms
| Article | Year |
|---|---|
Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Line, Tumor; Humans; Mic | 2022 |
Antitumor effect of poly lactic acid nanoparticles loaded with cisplatin and chloroquine on the oral squamous cell carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Prolif | 2020 |
In vitro and in vivo antitumor effects of chloroquine on oral squamous cell carcinoma.
Topics: Animals; Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Chlor | 2017 |
Tetrandrine induces cell death in SAS human oral cancer cells through caspase activation-dependent apoptosis and LC3-I and LC3-II activation-dependent autophagy.
Topics: Antineoplastic Agents, Phytogenic; Antirheumatic Agents; Apoptosis; Apoptosis Regulatory Proteins; A | 2013 |
Long-term stimulation of areca nut components results in increased chemoresistance through elevated autophagic activity.
Topics: Actins; Adenine; Antimetabolites, Antineoplastic; Antineoplastic Agents; Areca; Autophagy; Autophagy | 2014 |
G15, a GPR30 antagonist, induces apoptosis and autophagy in human oral squamous carcinoma cells.
Topics: Apoptosis; Autophagy; Benzodioxoles; Carcinoma, Squamous Cell; Caspases; Cell Line, Tumor; Chloroqui | 2013 |
[Mechanism of chloroquine in promoting sensitivity of chemotherapeutics in oral squamous cell carcinoma CAL-27 cell line to cisplatin].
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Line, Tumor; Chloroquine | 2015 |
Role of a low-pH environment in adenovirus enhancement of the toxicity of a Pseudomonas exotoxin-epidermal growth factor conjugate.
Topics: Adenoviruses, Human; Amines; Ammonium Chloride; Carcinoma; Cell Line; Chloroquine; Drug Synergism; E | 1984 |
Adenovirus-dependent release of 51Cr from KB cells at an acidic pH.
Topics: Adenoviruses, Human; ADP Ribose Transferases; Bacterial Toxins; Carcinoma; Cell Transformation, Vira | 1984 |
[Clinical observations on lichen planus of the oral cavity].
Topics: Adult; Aged; Cheek; Chloroquine; Female; Germany, East; Humans; Lichen Planus; Lip Diseases; Male; M | 1972 |