chloroquine has been researched along with Mesothelioma in 1 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Mesothelioma: A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report that, in each cell line, the toxic effects of CQ were amplified by nutritional stress and paralleled by autophagy inhibition." | 5.38 | Nutritional stress and arginine auxotrophy confer high sensitivity to chloroquine toxicity in mesothelioma cells. ( Albonici, L; Battisti, S; Bei, R; Modesti, A; Palumbo, C; Valente, D, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Battisti, S | 1 |
| Valente, D | 1 |
| Albonici, L | 1 |
| Bei, R | 1 |
| Modesti, A | 1 |
| Palumbo, C | 1 |
1 other study available for chloroquine and Mesothelioma
| Article | Year |
|---|---|
Nutritional stress and arginine auxotrophy confer high sensitivity to chloroquine toxicity in mesothelioma cells.
Topics: Arginine; Argininosuccinate Synthase; Autophagy; Cell Death; Cell Line, Tumor; Chloroquine; Humans; | 2012 |