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chloroquine and Lung Injury, Acute

chloroquine has been researched along with Lung Injury, Acute in 4 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Research Excerpts

ExcerptRelevanceReference
"This study preliminarily investigated the mechanism by which chloroquine (CQ) relieves acute lung injury (ALI) complicated in acute hemorrhagic necrotizing pancreatitis (AHNP)."7.79Chloroquine relieves acute lung injury in rats with acute hemorrhagic necrotizing pancreatitis. ( Chen, XP; Chen, Y; Wang, CY; Wang, L; Wu, HS; Zhang, L; Zhang, WG, 2013)
"This study preliminarily investigated the mechanism by which chloroquine (CQ) relieves acute lung injury (ALI) complicated in acute hemorrhagic necrotizing pancreatitis (AHNP)."3.79Chloroquine relieves acute lung injury in rats with acute hemorrhagic necrotizing pancreatitis. ( Chen, XP; Chen, Y; Wang, CY; Wang, L; Wu, HS; Zhang, L; Zhang, WG, 2013)
" Furthermore, autophagy intervention experiments were achieved by the administration of rapamycin (RAPA) or chloroquine (CQ) one hour prior to dosing 300 mg/kg APAP."1.51Mitophagy protects against acetaminophen-induced acute liver injury in mice through inhibiting NLRP3 inflammasome activation. ( Kou, R; Shan, S; Shen, Z; Song, F; Xie, K; Zhang, C, 2019)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Shan, S1
Shen, Z1
Zhang, C1
Kou, R1
Xie, K1
Song, F1
Guo, L1
Wu, X1
Zhao, S1
Zhang, X1
Qian, G1
Li, S1
Zhang, L2
Chen, Y1
Wang, L1
Chen, XP1
Zhang, WG1
Wang, CY1
Wu, HS1
Shen, H1
Wu, N1
Wang, Y1
Zhao, H1
Li, T1
Zhao, M1

Other Studies

4 other studies available for chloroquine and Lung Injury, Acute

ArticleYear
Mitophagy protects against acetaminophen-induced acute liver injury in mice through inhibiting NLRP3 inflammasome activation.
    Biochemical pharmacology, 2019, Volume: 169

    Topics: Acetaminophen; Acute Lung Injury; Animals; Chloroquine; Inflammasomes; Male; Mice; Mice, Inbred C57B

2019
Autophagy inhibition protects from alveolar barrier dysfunction in LPS-induced ALI mice by targeting alveolar epithelial cells.
    Respiratory physiology & neurobiology, 2021, Volume: 283

    Topics: Acute Lung Injury; Adenine; Alveolar Epithelial Cells; Animals; Autophagy; Bronchoalveolar Lavage Fl

2021
Chloroquine relieves acute lung injury in rats with acute hemorrhagic necrotizing pancreatitis.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2013, Volume: 33, Issue:3

    Topics: Acute Lung Injury; Animals; Chloroquine; Cytokines; Male; Pancreatitis, Acute Necrotizing; Rats; Rat

2013
Chloroquine attenuates paraquat-induced lung injury in mice by altering inflammation, oxidative stress and fibrosis.
    International immunopharmacology, 2017, Volume: 46

    Topics: Actins; Acute Lung Injury; Animals; Anti-Inflammatory Agents; Chloroquine; Cytokines; Humans; Inflam

2017