chloroquine has been researched along with Liver Neoplasms in 63 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Liver Neoplasms: Tumors or cancer of the LIVER.
Excerpt | Relevance | Reference |
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" This study aimed to evaluate chloroquine's (CQ) ability to trigger TRAIL/TRAILR2 apoptotic pathway in thioacetamide (TAA)-induced hepatocellular carcinoma (HCC) either alone or in combination with doxorubicin (DOX)." | 7.88 | Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model. ( Eissa, LA; El Gayar, AM; El-Karef, A; El-Mesery, M; Helmy, SA, 2018) |
"To investigate the effect of chloroquine in inducing apoptosis of human hepatocellular carcinoma cells and explore the possible mechanism." | 7.88 | [Chloroquine induces apoptosis of human hepatocellular carcinoma cells in vitro by miR-26b-mediated regulation of Mcl-1]. ( Jiang, CC; Liu, H; Ma, LY; Sun, XJ; Wang, Y; Zhang, MX; Zhang, P, 2018) |
" Here, we explored the impact of salvianolic acid B (Sal B), the major water-soluble compounds of Danshen, on apoptosis and autophagy of human hepatocellular carcinoma cells (HCC)." | 7.83 | AKT/mTOR signaling pathway is involved in salvianolic acid B-induced autophagy and apoptosis in hepatocellular carcinoma cells. ( Chen, G; Chen, P; Di, C; Gong, L; Shi, J; Wang, J; Xia, X; Xu, H; Zhang, W, 2016) |
"Luteolin induced apoptosis in human liver cancer SMMC-7721 cells, partially via autophagy." | 5.46 | Luteolin Promotes Cell Apoptosis by Inducing Autophagy in Hepatocellular Carcinoma. ( Cai, X; Cao, Z; Chai, D; Chen, H; Chu, F; Fang, W; Wen, Y; Zhang, H; Zhang, Y, 2017) |
"Sorafenib treatment led to accumulation of autophagosomes as evidenced by conversion from LC3-I to LC3-II observed by immunoblot in Huh7, HLF and PLC/PRF/5 cells." | 5.38 | Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma. ( Fujita, N; Hayashi, N; Hikita, H; Hiramatsu, N; Hosui, A; Ishida, H; Kanto, T; Kodama, T; Miyagi, T; Shimizu, S; Takehara, T; Tatsumi, T; Tsunematsu, H; Yoshimori, T, 2012) |
" MATERIAL AND METHODS SMMC-7721 cells (a hepatocellular carcinoma cell line) were treated with different concentrations of oleanolic acid (OA) plus autophagy inhibitor 3-methyladenine (3-MA) (3-MA+OA) or chloroquine (CQ) plus OA (CQ+OA)." | 3.96 | Effect of Oleanolic Acid on Apoptosis and Autophagy of SMMC-7721 Hepatoma Cells. ( Wu, X; Zeng, X; Zhou, W, 2020) |
" This study aimed to evaluate chloroquine's (CQ) ability to trigger TRAIL/TRAILR2 apoptotic pathway in thioacetamide (TAA)-induced hepatocellular carcinoma (HCC) either alone or in combination with doxorubicin (DOX)." | 3.88 | Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model. ( Eissa, LA; El Gayar, AM; El-Karef, A; El-Mesery, M; Helmy, SA, 2018) |
"To investigate the effect of chloroquine in inducing apoptosis of human hepatocellular carcinoma cells and explore the possible mechanism." | 3.88 | [Chloroquine induces apoptosis of human hepatocellular carcinoma cells in vitro by miR-26b-mediated regulation of Mcl-1]. ( Jiang, CC; Liu, H; Ma, LY; Sun, XJ; Wang, Y; Zhang, MX; Zhang, P, 2018) |
" Here, we explored the impact of salvianolic acid B (Sal B), the major water-soluble compounds of Danshen, on apoptosis and autophagy of human hepatocellular carcinoma cells (HCC)." | 3.83 | AKT/mTOR signaling pathway is involved in salvianolic acid B-induced autophagy and apoptosis in hepatocellular carcinoma cells. ( Chen, G; Chen, P; Di, C; Gong, L; Shi, J; Wang, J; Xia, X; Xu, H; Zhang, W, 2016) |
"Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive deposition of droplets in hepatocytes." | 1.51 | Immunohistochemical expression of autophagosome markers LC3 and p62 in preneoplastic liver foci in high fat diet-fed rats. ( Eguchi, A; Ichikawa, R; Masuda, S; Mizukami, S; Nakamura, K; Nakamura, M; Okada, R; Shibutani, M; Tanaka, T; Yoshida, T, 2019) |
"The growth inhibition and autophagy of liver cancer cells were detected using acridine orange fluorescence staining, flow cytometry and transmission electron microscopy." | 1.48 | The biological role of autophagy in regulating and controlling the proliferation of liver cancer cells induced by bufalin. ( Li, Q; Qin, J; Sheng, X; Zhu, P, 2018) |
"Luteolin induced apoptosis in human liver cancer SMMC-7721 cells, partially via autophagy." | 1.46 | Luteolin Promotes Cell Apoptosis by Inducing Autophagy in Hepatocellular Carcinoma. ( Cai, X; Cao, Z; Chai, D; Chen, H; Chu, F; Fang, W; Wen, Y; Zhang, H; Zhang, Y, 2017) |
"Liver cancer is the second-most frequent cause of cancer death in the world and is highly treatment resistant." | 1.42 | Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer. ( Chen, P; Chu, Y; Dong, Z; Hoffman, RM; Hu, T; Jeong, LS; Jia, L; Jiang, Y; Li, C; Li, P; Liang, Y; Pan, Y; Qi, H; Wei, D; Yang, M; Zhang, P, 2015) |
"Invasion of hepatocellular carcinoma (HCC) cells is a leading cause of intrahepatic dissemination and metastasis." | 1.39 | Autophagy promotes hepatocellular carcinoma cell invasion through activation of epithelial-mesenchymal transition. ( Guo, Y; Li, J; Shang, D; Song, Z; Wu, Y; Xiong, J; Yang, B; Zheng, Q; Zhou, Q, 2013) |
"Sorafenib treatment led to accumulation of autophagosomes as evidenced by conversion from LC3-I to LC3-II observed by immunoblot in Huh7, HLF and PLC/PRF/5 cells." | 1.38 | Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma. ( Fujita, N; Hayashi, N; Hikita, H; Hiramatsu, N; Hosui, A; Ishida, H; Kanto, T; Kodama, T; Miyagi, T; Shimizu, S; Takehara, T; Tatsumi, T; Tsunematsu, H; Yoshimori, T, 2012) |
"This phenomenon is specific for hepatoma cell lines or primarily cultured hepatocytes." | 1.32 | pH-dependent translocation of alpha-tocopherol transfer protein (alpha-TTP) between hepatic cytosol and late endosomes. ( Arai, H; Arita, M; Horiguchi, M; Inoue, K; Kaempf-Rotzoll, DE; Tsujimoto, M, 2003) |
"Human hepatoma cells took up Hb-Hp in a receptor-mediated manner." | 1.28 | Expression of haptoglobin receptors in human hepatoma cells. ( Okuda, M; Taketani, S; Tokunaga, R, 1992) |
"The Fu5AH rat hepatoma cell line accumulates cholesteryl ester (CE) upon incubation in medium supplemented with hyperlipemic serum or hyperlipemic serum lipoproteins." | 1.26 | Origin of fatty acids of cholesteryl ester accumulated by Fu5AH cells in culture. ( Rosen, JM; Rothblat, GH, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 17 (26.98) | 18.7374 |
1990's | 9 (14.29) | 18.2507 |
2000's | 2 (3.17) | 29.6817 |
2010's | 26 (41.27) | 24.3611 |
2020's | 9 (14.29) | 2.80 |
Authors | Studies |
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Xu, F | 1 |
Tautenhahn, HM | 1 |
Dirsch, O | 1 |
Dahmen, U | 1 |
Kaur, R | 1 |
Kanthaje, S | 1 |
Taneja, S | 1 |
Dhiman, RK | 1 |
Chakraborti, A | 1 |
Okubo, S | 1 |
Ohta, T | 1 |
Shoyama, Y | 1 |
Uto, T | 1 |
Zhou, W | 1 |
Zeng, X | 1 |
Wu, X | 2 |
Morin, G | 1 |
Pinel, K | 1 |
Dias, K | 1 |
Seiliez, I | 1 |
Beaumatin, F | 1 |
Nguépy Keubo, FR | 1 |
Mboua, PC | 1 |
Djifack Tadongfack, T | 1 |
Fokouong Tchoffo, E | 1 |
Tasson Tatang, C | 1 |
Ide Zeuna, J | 1 |
Noupoue, EM | 1 |
Tsoplifack, CB | 1 |
Folefack, GO | 1 |
Kettani, M | 1 |
Bandelier, P | 1 |
Huo, J | 1 |
Li, H | 4 |
Yu, D | 1 |
Arulsamy, N | 1 |
AlAbbad, S | 1 |
Sardot, T | 1 |
Lekashvili, O | 1 |
Decato, D | 1 |
Lelj, F | 1 |
Alexander Ross, JB | 1 |
Rosenberg, E | 1 |
Nazir, H | 1 |
Muthuswamy, N | 1 |
Louis, C | 1 |
Jose, S | 1 |
Prakash, J | 1 |
Buan, MEM | 1 |
Flox, C | 1 |
Chavan, S | 1 |
Shi, X | 1 |
Kauranen, P | 1 |
Kallio, T | 1 |
Maia, G | 1 |
Tammeveski, K | 1 |
Lymperopoulos, N | 1 |
Carcadea, E | 1 |
Veziroglu, E | 1 |
Iranzo, A | 1 |
M Kannan, A | 1 |
Arunamata, A | 1 |
Tacy, TA | 1 |
Kache, S | 1 |
Mainwaring, RD | 1 |
Ma, M | 1 |
Maeda, K | 1 |
Punn, R | 1 |
Noguchi, S | 1 |
Hahn, S | 3 |
Iwasa, Y | 3 |
Ling, J | 2 |
Voccio, JP | 2 |
Kim, Y | 3 |
Song, J | 3 |
Bascuñán, J | 2 |
Chu, Y | 2 |
Tomita, M | 1 |
Cazorla, M | 1 |
Herrera, E | 1 |
Palomeque, E | 1 |
Saud, N | 1 |
Hoplock, LB | 1 |
Lobchuk, MM | 1 |
Lemoine, J | 1 |
Li, X | 11 |
Henson, MA | 1 |
Unsihuay, D | 1 |
Qiu, J | 1 |
Swaroop, S | 1 |
Nagornov, KO | 1 |
Kozhinov, AN | 1 |
Tsybin, YO | 1 |
Kuang, S | 1 |
Laskin, J | 1 |
Zin, NNINM | 1 |
Mohamad, MN | 1 |
Roslan, K | 1 |
Abdul Wafi, S | 1 |
Abdul Moin, NI | 1 |
Alias, A | 1 |
Zakaria, Y | 1 |
Abu-Bakar, N | 1 |
Naveed, A | 1 |
Jilani, K | 1 |
Siddique, AB | 1 |
Akbar, M | 1 |
Riaz, M | 1 |
Mushtaq, Z | 1 |
Sikandar, M | 1 |
Ilyas, S | 1 |
Bibi, I | 1 |
Asghar, A | 1 |
Rasool, G | 1 |
Irfan, M | 1 |
Li, XY | 1 |
Zhao, S | 1 |
Fan, XH | 1 |
Chen, KP | 1 |
Hua, W | 1 |
Liu, ZM | 1 |
Xue, XD | 1 |
Zhou, B | 1 |
Zhang, S | 3 |
Xing, YL | 1 |
Chen, MA | 1 |
Sun, Y | 1 |
Neradilek, MB | 1 |
Wu, XT | 1 |
Zhang, D | 2 |
Huang, W | 1 |
Cui, Y | 1 |
Yang, QQ | 1 |
Li, HW | 1 |
Zhao, XQ | 1 |
Hossein Rashidi, B | 1 |
Tarafdari, A | 1 |
Ghazimirsaeed, ST | 1 |
Shahrokh Tehraninezhad, E | 1 |
Keikha, F | 1 |
Eslami, B | 1 |
Ghazimirsaeed, SM | 1 |
Jafarabadi, M | 1 |
Silvani, Y | 1 |
Lovita, AND | 1 |
Maharani, A | 1 |
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Sujuti, H | 1 |
Ratnawati, R | 1 |
Raras, TYM | 1 |
Lemin, AS | 1 |
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Pangarah, CA | 1 |
Kiyu, A | 1 |
Zeng, C | 2 |
Du, H | 1 |
Lin, D | 1 |
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Rubagumya, F | 1 |
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Vanderpuye, V | 1 |
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Hammad, N | 1 |
Sajo, EA | 1 |
Okunade, KS | 1 |
Olorunfemi, G | 1 |
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Anorlu, RI | 1 |
Xu, C | 2 |
Xiang, Y | 1 |
Xu, X | 2 |
Zhou, L | 2 |
Dong, X | 1 |
Tang, S | 2 |
Gao, XC | 1 |
Wei, CH | 1 |
Zhang, RG | 1 |
Cai, Q | 1 |
He, Y | 1 |
Tong, F | 1 |
Dong, JH | 1 |
Wu, G | 1 |
Dong, XR | 1 |
Tang, X | 1 |
Tao, F | 1 |
Xiang, W | 1 |
Zhao, Y | 2 |
Jin, L | 1 |
Tao, H | 1 |
Lei, Y | 1 |
Gan, H | 1 |
Huang, Y | 1 |
Chen, Y | 5 |
Chen, L | 3 |
Shan, A | 1 |
Zhao, H | 2 |
Wu, M | 2 |
Ma, Q | 1 |
Wang, J | 5 |
Zhang, E | 1 |
Zhang, J | 4 |
Li, Y | 5 |
Xue, F | 1 |
Deng, L | 1 |
Liu, L | 2 |
Yan, Z | 2 |
Wang, Y | 3 |
Meng, J | 1 |
Chen, G | 3 |
Anastassiadou, M | 1 |
Bernasconi, G | 1 |
Brancato, A | 1 |
Carrasco Cabrera, L | 1 |
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Theobald, A | 1 |
Vagenende, B | 1 |
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Du, L | 1 |
Liu, X | 1 |
Ren, Y | 1 |
Li, J | 8 |
Li, P | 3 |
Jiao, Q | 1 |
Meng, P | 1 |
Wang, F | 2 |
Wang, YS | 1 |
Wang, C | 4 |
Zhou, X | 2 |
Wang, W | 2 |
Wang, S | 2 |
Hou, J | 1 |
Zhang, A | 1 |
Lv, B | 1 |
Gao, C | 2 |
Pang, D | 1 |
Lu, K | 1 |
Ahmad, NH | 1 |
Wang, L | 2 |
Zhu, J | 2 |
Zhang, L | 2 |
Zhuang, T | 1 |
Tu, J | 1 |
Zhao, Z | 1 |
Qu, Y | 1 |
Yao, H | 1 |
Wang, X | 6 |
Lee, DF | 1 |
Shen, J | 3 |
Wen, L | 1 |
Huang, G | 3 |
Xie, X | 1 |
Zhao, Q | 1 |
Hu, W | 1 |
Zhang, Y | 7 |
Lu, J | 2 |
Li, M | 1 |
Li, W | 3 |
Wu, W | 1 |
Du, F | 1 |
Ji, H | 1 |
Yang, X | 2 |
Xu, Z | 1 |
Wan, L | 1 |
Wen, Q | 1 |
Cho, CH | 1 |
Zou, C | 1 |
Xiao, Z | 1 |
Liao, J | 1 |
Su, X | 1 |
Bi, Z | 1 |
Su, Q | 1 |
Huang, H | 1 |
Wei, Y | 2 |
Gao, Y | 2 |
Na, KJ | 1 |
Choi, H | 1 |
Oh, HR | 1 |
Kim, YH | 1 |
Lee, SB | 1 |
Jung, YJ | 1 |
Koh, J | 1 |
Park, S | 1 |
Lee, HJ | 1 |
Jeon, YK | 1 |
Chung, DH | 1 |
Paeng, JC | 1 |
Park, IK | 1 |
Kang, CH | 1 |
Cheon, GJ | 1 |
Kang, KW | 1 |
Lee, DS | 1 |
Kim, YT | 1 |
Pajuelo-Lozano, N | 1 |
Alcalá, S | 1 |
Sainz, B | 1 |
Perona, R | 1 |
Sanchez-Perez, I | 1 |
Logotheti, S | 1 |
Marquardt, S | 1 |
Gupta, SK | 1 |
Richter, C | 1 |
Edelhäuser, BAH | 1 |
Engelmann, D | 1 |
Brenmoehl, J | 1 |
Söhnchen, C | 1 |
Murr, N | 1 |
Alpers, M | 1 |
Singh, KP | 1 |
Wolkenhauer, O | 1 |
Heckl, D | 1 |
Spitschak, A | 1 |
Pützer, BM | 1 |
Liao, Y | 1 |
Cheng, J | 3 |
Kong, X | 1 |
Li, S | 2 |
Zhang, M | 4 |
Zhang, H | 4 |
Yang, T | 2 |
Dong, Y | 1 |
Xu, Y | 1 |
Yuan, Z | 1 |
Cao, J | 1 |
Zheng, Y | 2 |
Luo, Z | 2 |
Mei, Z | 1 |
Yao, Y | 2 |
Liu, Z | 2 |
Liang, C | 1 |
Yang, H | 2 |
Song, Y | 1 |
Yu, K | 1 |
Zhu, C | 1 |
Huang, Z | 1 |
Qian, J | 1 |
Ge, J | 1 |
Hu, J | 2 |
Wang, H | 2 |
Liu, Y | 4 |
Mi, Y | 1 |
Kong, H | 1 |
Xi, D | 1 |
Yan, W | 1 |
Luo, X | 1 |
Ning, Q | 1 |
Chang, X | 2 |
Zhang, T | 2 |
Wang, Q | 3 |
Rathore, MG | 1 |
Reddy, K | 1 |
Chen, H | 2 |
Shin, SH | 1 |
Ma, WY | 1 |
Bode, AM | 1 |
Dong, Z | 3 |
Mu, W | 1 |
Liu, C | 3 |
Gao, F | 1 |
Qi, Y | 1 |
Lu, H | 1 |
Zhang, X | 6 |
Cai, X | 2 |
Ji, RY | 1 |
Hou, Y | 3 |
Tian, J | 2 |
Shi, Y | 1 |
Ying, S | 1 |
Tan, M | 1 |
Feng, G | 1 |
Kuang, Y | 1 |
Chen, D | 1 |
Wu, D | 3 |
Zhu, ZQ | 1 |
Tang, HX | 1 |
Shi, ZE | 1 |
Kang, J | 1 |
Liu, Q | 1 |
Qi, J | 2 |
Mu, J | 1 |
Cong, Z | 1 |
Chen, S | 2 |
Fu, D | 1 |
Li, Z | 2 |
Celestrin, CP | 1 |
Rocha, GZ | 1 |
Stein, AM | 1 |
Guadagnini, D | 1 |
Tadelle, RM | 1 |
Saad, MJA | 1 |
Oliveira, AG | 1 |
Bianconi, V | 1 |
Bronzo, P | 1 |
Banach, M | 1 |
Sahebkar, A | 1 |
Mannarino, MR | 1 |
Pirro, M | 1 |
Patsourakos, NG | 1 |
Kouvari, M | 1 |
Kotidis, A | 1 |
Kalantzi, KI | 1 |
Tsoumani, ME | 1 |
Anastasiadis, F | 1 |
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Efraimidis, P | 1 |
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Gerakiou, K | 1 |
Grigoriadou-Skouta, E | 1 |
Grigoropoulos, P | 1 |
Hatzopoulos, D | 1 |
Kartalis, A | 1 |
Lyras, A | 1 |
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Mikrogeorgiou, A | 1 |
Myroforou, I | 1 |
Orkopoulos, A | 1 |
Pavlidis, P | 1 |
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Skouloudi, M | 1 |
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Thomaidis, K | 1 |
Tsikouri, GE | 1 |
Tsikouris, EI | 1 |
Zisimos, K | 1 |
Vavoulis, P | 1 |
Vitali, MG | 1 |
Vitsas, G | 1 |
Vogiatzidis, C | 1 |
Chantanis, S | 1 |
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Panagiotakos, DB | 1 |
Tselepis, AD | 1 |
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Kuklik, P | 1 |
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Schwarzl, J | 1 |
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Pogorzelski, A | 1 |
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Grytczuk, M | 1 |
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Xi, J | 1 |
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Chen, W | 3 |
Hu, X | 1 |
Zhang, F | 1 |
Wei, H | 1 |
Wang, Z | 1 |
Gurzu, S | 1 |
Jung, I | 1 |
Sugimura, H | 2 |
Stefan-van Staden, RI | 1 |
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Natsume, H | 1 |
Iwashita, Y | 1 |
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Validad, MH | 1 |
Langroudi, FH | 1 |
Esfandiari, H | 1 |
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Mets-Halgrimson, R | 1 |
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Zeid, JL | 1 |
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Araujo-Castillo, RV | 1 |
Culquichicón, C | 1 |
Solis Condor, R | 1 |
Efendi, F | 1 |
Sebayang, SK | 1 |
Astutik, E | 1 |
Hadisuyatmana, S | 1 |
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Kuswanto, H | 1 |
Foroutan, T | 1 |
Ahmadi, F | 1 |
Moayer, F | 1 |
Khalvati, S | 1 |
Zhang, Q | 2 |
Lyu, Y | 1 |
Huang, J | 1 |
Yu, N | 1 |
Wen, Z | 1 |
Hou, H | 1 |
Zhao, T | 1 |
Gupta, A | 1 |
Khosla, N | 1 |
Govindasamy, V | 1 |
Saini, A | 1 |
Annapurna, K | 1 |
Dhakate, SR | 1 |
Akkaya, Ö | 1 |
Chandgude, AL | 1 |
Dömling, A | 1 |
Harnett, J | 1 |
Oakes, K | 1 |
Carè, J | 1 |
Leach, M | 1 |
Brown, D | 1 |
Cramer, H | 1 |
Pinder, TA | 1 |
Steel, A | 1 |
Anheyer, D | 1 |
Cantu, J | 1 |
Valle, J | 1 |
Flores, K | 1 |
Gonzalez, D | 1 |
Valdes, C | 1 |
Lopez, J | 1 |
Padilla, V | 1 |
Alcoutlabi, M | 1 |
Parsons, J | 1 |
Núñez, K | 1 |
Hamed, M | 1 |
Fort, D | 1 |
Bruce, D | 1 |
Thevenot, P | 1 |
Cohen, A | 1 |
Weber, P | 1 |
Menezes, AMB | 1 |
Gonçalves, H | 1 |
Perez-Padilla, R | 1 |
Jarvis, D | 1 |
de Oliveira, PD | 1 |
Wehrmeister, FC | 1 |
Mir, S | 1 |
Wong, J | 1 |
Ryan, CM | 1 |
Bellingham, G | 1 |
Singh, M | 2 |
Waseem, R | 1 |
Eckert, DJ | 1 |
Chung, F | 1 |
Hegde, H | 1 |
Shimpi, N | 1 |
Panny, A | 1 |
Glurich, I | 1 |
Christie, P | 1 |
Acharya, A | 1 |
English, KL | 1 |
Downs, M | 1 |
Goetchius, E | 1 |
Buxton, R | 1 |
Ryder, JW | 1 |
Ploutz-Snyder, R | 1 |
Guilliams, M | 1 |
Scott, JM | 1 |
Ploutz-Snyder, LL | 1 |
Martens, C | 1 |
Goplen, FK | 1 |
Aasen, T | 1 |
Gjestad, R | 1 |
Nordfalk, KF | 1 |
Nordahl, SHG | 1 |
Inoue, T | 1 |
Soshi, S | 1 |
Kubota, M | 1 |
Marumo, K | 1 |
Mortensen, NP | 1 |
Caffaro, MM | 1 |
Patel, PR | 2 |
Uddin, MJ | 1 |
Aravamudhan, S | 1 |
Sumner, SJ | 1 |
Fennell, TR | 1 |
Gal, RL | 1 |
Cohen, NJ | 1 |
Kruger, D | 1 |
Beck, RW | 1 |
Bergenstal, RM | 1 |
Calhoun, P | 1 |
Cushman, T | 1 |
Haban, A | 1 |
Hood, K | 1 |
Johnson, ML | 1 |
McArthur, T | 1 |
Olson, BA | 1 |
Weinstock, RS | 1 |
Oser, SM | 1 |
Oser, TK | 1 |
Bugielski, B | 1 |
Strayer, H | 1 |
Aleppo, G | 1 |
Maruyama, H | 1 |
Hirayama, K | 1 |
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Knowles, B | 1 |
Alaupovic, P | 2 |
Hajjar, KA | 1 |
Reynolds, CM | 1 |
Erbacher, P | 1 |
Roche, AC | 1 |
Monsigny, M | 1 |
Midoux, P | 1 |
Rosen, JM | 1 |
Rothblat, GH | 1 |
Muhlbauer, JE | 1 |
Pathak, MA | 1 |
Suzuki, S | 1 |
Florén, CH | 1 |
Underhill, DM | 1 |
Owensby, DA | 1 |
Morton, PA | 1 |
Okuda, M | 1 |
Tokunaga, R | 1 |
Taketani, S | 1 |
Odum, L | 1 |
el-Mofty, MM | 1 |
Khudoley, VV | 1 |
Sakr, SA | 1 |
Abdel-Gawad, HS | 1 |
Sathre, KA | 1 |
Tsang, ML | 1 |
Weatherbee, JA | 1 |
Steer, CJ | 1 |
Smith, RM | 1 |
Jarett, L | 1 |
Pittman, RC | 1 |
Knecht, TP | 1 |
Rosenbaum, MS | 1 |
Taylor, CA | 1 |
McClain, DA | 1 |
Olefsky, JM | 1 |
Hortin, G | 1 |
Strauss, AW | 1 |
Granot, E | 1 |
Tabas, I | 1 |
Tall, AR | 1 |
Braulke, T | 1 |
Geuze, HJ | 1 |
Slot, JW | 1 |
Hasilik, A | 1 |
von Figura, K | 1 |
Peters, M | 1 |
Frenzel, H | 1 |
Kade, H | 1 |
Boyd, CM | 1 |
Lieberman, LM | 1 |
Beierwaltes, WH | 1 |
Varma, VM | 1 |
Johnston, GS | 1 |
Jones, AE | 1 |
4 reviews available for chloroquine and Liver Neoplasms
Article | Year |
---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Nrf2-p62 autophagy pathway and its response to oxidative stress in hepatocellular carcinoma.
Topics: Animals; Autophagy; Carcinoma, Hepatocellular; Chloroquine; Humans; Hydroxychloroquine; Liver Neopla | 2018 |
Immunological and anti-viral therapy of chronic hepatitis B virus infection.
Topics: Adjuvants, Immunologic; Antibody Formation; Antiviral Agents; Carcinoma, Hepatocellular; Chloroquine | 1980 |
Porphyria cutanea tarda.
Topics: Adolescent; Aged; Alcoholism; Animals; Chick Embryo; Child; Chloroquine; Diagnosis, Differential; He | 1979 |
2 trials available for chloroquine and Liver Neoplasms
Article | Year |
---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Diagnostic efficacy of a radioiodinated chloroquine analog in patients with malignant melanoma.
Topics: Brain Neoplasms; Chloroquine; Clinical Trials as Topic; Eye Neoplasms; Humans; Iodine Radioisotopes; | 1970 |
58 other studies available for chloroquine and Liver Neoplasms
Article | Year |
---|---|
Blocking autophagy with chloroquine aggravates lipid accumulation and reduces intracellular energy synthesis in hepatocellular carcinoma cells, both contributing to its anti-proliferative effect.
Topics: Adenosine Triphosphate; Autophagy; Autophagy-Related Proteins; Carcinoma, Hepatocellular; Cell Line, | 2022 |
miR-23b-3p Modulating Cytoprotective Autophagy and Glutamine Addiction in Sorafenib Resistant HepG2, a Hepatocellular Carcinoma Cell Line.
Topics: Autophagy; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Gene Expression Regulation, Neoplastic | 2022 |
Arctigenin suppresses cell proliferation via autophagy inhibition in hepatocellular carcinoma cells.
Topics: Adenine; Apoptosis; Apoptosis Regulatory Proteins; Arctium; Autophagy; Carcinoma, Hepatocellular; Ce | 2020 |
Effect of Oleanolic Acid on Apoptosis and Autophagy of SMMC-7721 Hepatoma Cells.
Topics: Adenine; Adenosine Triphosphate; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; | 2020 |
RTH-149 Cell Line, a Useful Tool to Decipher Molecular Mechanisms Related to Fish Nutrition.
Topics: Amino Acids; Animals; Aquaculture; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Chloroqui | 2020 |
BCAT1 decreases the sensitivity of cancer cells to cisplatin by regulating mTOR-mediated autophagy via branched-chain amino acid metabolism.
Topics: Amino Acids, Branched-Chain; Animals; Antineoplastic Agents; Autophagy; Carcinoma, Hepatocellular; C | 2021 |
Methyl gallate, gallic acid-derived compound, inhibit cell proliferation through increasing ROS production and apoptosis in hepatocellular carcinoma cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Carcinoma, Hepatocell | 2021 |
HSF1 upregulates ATG4B expression and enhances epirubicin-induced protective autophagy in hepatocellular carcinoma cells.
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Autophagy; Autophagy-Related Proteins; Carcinoma, Hep | 2017 |
Luteolin Promotes Cell Apoptosis by Inducing Autophagy in Hepatocellular Carcinoma.
Topics: Apoptosis; Autophagosomes; Autophagy; Beclin-1; Blotting, Western; Carcinoma, Hepatocellular; Caspas | 2017 |
Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model.
Topics: Animals; Carcinoma, Hepatocellular; Caspases; Chloroquine; Doxorubicin; Gene Expression Regulation; | 2018 |
The biological role of autophagy in regulating and controlling the proliferation of liver cancer cells induced by bufalin.
Topics: Adenine; Autophagy; Beclin-1; Bufanolides; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; | 2018 |
[Chloroquine induces apoptosis of human hepatocellular carcinoma cells in vitro by miR-26b-mediated regulation of Mcl-1].
Topics: Adenosine Triphosphate; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Chloroquine; Hep G | 2018 |
Attenuation of autophagy flux by 6-shogaol sensitizes human liver cancer cells to TRAIL-induced apoptosis via p53 and ROS.
Topics: Acetylcysteine; Apoptosis; Autophagy; Caspases, Initiator; Catechols; Cell Line, Tumor; Chloroquine; | 2019 |
Targeting PARP and autophagy evoked synergistic lethality in hepatocellular carcinoma.
Topics: Animals; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Proliferation; Chloroquine; Drug Syne | 2020 |
Immunohistochemical expression of autophagosome markers LC3 and p62 in preneoplastic liver foci in high fat diet-fed rats.
Topics: Amiodarone; Animals; Autophagosomes; Autophagy; Autophagy-Related Protein 5; Chloroquine; Diet, High | 2019 |
Paradoxical role of autophagy in the dysplastic and tumor-forming stages of hepatocarcinoma development in rats.
Topics: Animals; Antioxidants; Autophagy; Carcinoma, Hepatocellular; Cell Proliferation; Cell Transformation | 2013 |
Autophagy promotes hepatocellular carcinoma cell invasion through activation of epithelial-mesenchymal transition.
Topics: Autophagy; Autophagy-Related Protein 7; Autophagy-Related Proteins; Carcinoma, Hepatocellular; Cell | 2013 |
Chloroquine promotes the anticancer effect of TACE in a rabbit VX2 liver tumor model.
Topics: ADAM Proteins; ADAM17 Protein; Animals; Antineoplastic Agents; Apoptosis; Chloroquine; Drug Synergis | 2013 |
Autophagy contributes to the survival of CD133+ liver cancer stem cells in the hypoxic and nutrient-deprived tumor microenvironment.
Topics: AC133 Antigen; Animals; Antigens, CD; Autophagy; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Chlo | 2013 |
Blocking autophagic flux enhances matrine-induced apoptosis in human hepatoma cells.
Topics: Adaptor Proteins, Signal Transducing; Alkaloids; Apoptosis; Apoptosis Regulatory Proteins; Autophagy | 2013 |
Effect of toll-like receptor 7 and 9 targeted therapy to prevent the development of hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Case-Control Studies; Cell Proliferation; Chloroquine; DNA; Hep | 2015 |
Carnosic acid induces autophagic cell death through inhibition of the Akt/mTOR pathway in human hepatoma cells.
Topics: Abietanes; Adenine; Apoptosis; Autophagy; Cell Proliferation; Chloroquine; Gene Silencing; Hep G2 Ce | 2015 |
PROX1 promotes metabolic adaptation and fuels outgrowth of Wnt(high) metastatic colon cancer cells.
Topics: Animals; Apoptosis; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Chloroquine; Colo | 2014 |
Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells.
Topics: Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Chloroquine; Extracellular Signal-Regulated | 2015 |
NS5ATP9 Promotes Beclin 1-Dependent Starvation-Induced Autophagy of Hepatoblastoma Cells.
Topics: Adenine; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Carrier Proteins; Cell Proliferation; C | 2015 |
Regulation of MET receptor tyrosine kinase signaling by suppressor of cytokine signaling 1 in hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chlorocebus aethiops; Chlo | 2015 |
Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer.
Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Autophagy; Carcinoma, Hepatocellular; Cell Lin | 2015 |
Chloroquine inhibits hepatocellular carcinoma cell growth in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor; | 2016 |
Polyphyllin I induced-apoptosis is enhanced by inhibition of autophagy in human hepatocellular carcinoma cells.
Topics: Apoptosis; Autophagy; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Cell Proliferation; Chl | 2015 |
Codelivery of salinomycin and chloroquine by liposomes enables synergistic antitumor activity in vitro.
Topics: Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line, Tumor; | 2016 |
AKT/mTOR signaling pathway is involved in salvianolic acid B-induced autophagy and apoptosis in hepatocellular carcinoma cells.
Topics: Adenine; Antineoplastic Agents; Apoptosis; Autophagy; Beclin-1; Benzofurans; Carcinoma, Hepatocellul | 2016 |
Autophagy activation in hepatocellular carcinoma contributes to the tolerance of oxaliplatin via reactive oxygen species modulation.
Topics: Animals; Antimalarials; Antineoplastic Agents; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumo | 2011 |
Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Autophag | 2012 |
Cellular uptake and metabolism of DNA frayed wires.
Topics: Adenosine Triphosphate; Binding, Competitive; Carcinoma, Hepatocellular; Cell Nucleus; Cell Survival | 2003 |
pH-dependent translocation of alpha-tocopherol transfer protein (alpha-TTP) between hepatic cytosol and late endosomes.
Topics: Amino Acid Sequence; Androstadienes; Animals; Biological Transport; Brefeldin A; Carcinoma, Hepatoce | 2003 |
Epidermal growth factor stimulation of ornithine decarboxylase activity in a human hepatoma cell line.
Topics: Ammonium Chloride; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Colchicine; Cy | 1981 |
Recycling of the asialoglycoprotein receptor and the effect of lysosomotropic amines in hepatoma cells.
Topics: Asialoglycoprotein Receptor; Asialoglycoproteins; Carcinoma, Hepatocellular; Cell Line; Cell Membran | 1984 |
Catabolism of human low density lipoproteins by human hepatoma cell line HepG2.
Topics: Binding, Competitive; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Colchicine; Humans; Lipopro | 1984 |
alpha-Fucose-mediated binding and degradation of tissue-type plasminogen activator by HepG2 cells.
Topics: Ammonium Chloride; Azides; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Dose-Response Relation | 1994 |
The reduction of the positive charges of polylysine by partial gluconoylation increases the transfection efficiency of polylysine/DNA complexes.
Topics: Acylation; Amino Acid Sequence; Carcinoma, Hepatocellular; Chloroquine; DNA, Recombinant; Gluconates | 1997 |
Origin of fatty acids of cholesteryl ester accumulated by Fu5AH cells in culture.
Topics: Carcinoma, Hepatocellular; Cell Line; Chloroquine; Cholesterol; Cholesterol Esters; Culture Media; F | 1977 |
[Studies on lysosomes in hepatic disorders (author's transl)].
Topics: Acid Phosphatase; Animals; Chemical and Drug Induced Liver Injury; Chloroquine; Glucuronidase; Hexos | 1979 |
Polymyxin B enhances low density lipoprotein catabolism in hepatic and extrahepatic cells.
Topics: Animals; Calcium; Carcinoma, Hepatocellular; Cattle; Cells, Cultured; Chloroquine; Colchicine; Endot | 1992 |
Endocytosis and lysosomal delivery of tissue plasminogen activator-inhibitor 1 complexes in Hep G2 cells.
Topics: Ammonium Chloride; beta-N-Acetylhexosaminidases; Carcinoma, Hepatocellular; Chloroquine; Endocytosis | 1992 |
Expression of haptoglobin receptors in human hepatoma cells.
Topics: Biological Transport; Cadaverine; Carcinoma, Hepatocellular; Cells, Cultured; Chloroquine; Endocytos | 1992 |
Biosynthesis of inter-alpha-trypsin inhibitor and alpha 1-microglobulin in a human hepatoma cell line.
Topics: Alpha-Globulins; Carbohydrate Metabolism; Carbohydrates; Carcinoma, Hepatocellular; Chloroquine; Ele | 1992 |
The carcinogenicity of some antimalarial drugs using the Egyptian toad Bufo regularis as a biological test animal.
Topics: Animals; Antimalarials; Bufonidae; Chloroquine; Disease Models, Animal; Drug Combinations; Female; K | 1992 |
Binding and internalization of transforming growth factor-beta 1 by human hepatoma cells: evidence for receptor recycling.
Topics: Binding, Competitive; Carcinoma, Hepatocellular; Chloroquine; Cycloheximide; Humans; Hydrogen-Ion Co | 1991 |
Partial characterization of mechanism of insulin accumulation in H35 hepatoma cell nuclei.
Topics: Adenosine Triphosphate; Biological Transport; Carcinoma, Hepatocellular; Cell Nucleus; Chloroquine; | 1990 |
A nonendocytotic mechanism for the selective uptake of high density lipoprotein-associated cholesterol esters.
Topics: Adrenal Cortex Neoplasms; alpha-Fetoproteins; Animals; Apolipoprotein A-I; Apolipoproteins A; Asialo | 1987 |
Evidence for two independent pathways of insulin-receptor internalization in hepatocytes and hepatoma cells.
Topics: 2,4-Dinitrophenol; Animals; Biological Transport; Biotransformation; Carcinoma, Hepatocellular; Cell | 1988 |
Binding and degradation of human high-density lipoproteins by human hepatoma cell line HepG2.
Topics: Binding Sites; Carcinoma, Hepatocellular; Cell Line; Chemical Phenomena; Chemistry; Chloroquine; Cho | 1985 |
Studies on the binding and degradation of human very-low-density lipoproteins by human hepatoma cell line HepG2.
Topics: Apolipoproteins B; Apolipoproteins E; Binding, Competitive; Carcinoma, Hepatocellular; Cell Line; Ch | 1986 |
Effects of acidotropic compounds on the secretory pathway: inhibition of secretion and processing of the third and fourth components of complement.
Topics: Amantadine; Benzamidines; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Complement C3; Compleme | 1986 |
Human plasma cholesteryl ester transfer protein enhances the transfer of cholesteryl ester from high density lipoproteins into cultured HepG2 cells.
Topics: Carcinoma, Hepatocellular; Carrier Proteins; Cell Line; Chloroquine; Cholesterol Ester Transfer Prot | 1987 |
On the effects of weak bases and monensin on sorting and processing of lysosomal enzymes in human cells.
Topics: Ammonium Chloride; Carcinoma, Hepatocellular; Cathepsin D; Cell Line; Chloroquine; Fibroblasts; Huma | 1987 |
[Therapy of infections with clonorchis sinensis (author's transl)].
Topics: Adult; Anthelmintics; Benzenesulfonates; Carcinoma; Chloroquine; Clonorchiasis; Clonorchis sinensis; | 1973 |
Sequential liver scanning.
Topics: Adult; Breast Neoplasms; Chloroquine; Colonic Neoplasms; Dactinomycin; Emetine; Estrogens; Female; F | 1969 |