chloroquine has been researched along with Liver Failure in 3 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine and hydroxychloroquine are quinoline derivatives used to treat malaria." | 5.05 | Pharmacokinetics and Pharmacological Properties of Chloroquine and Hydroxychloroquine in the Context of COVID-19 Infection. ( Cook, J; Joshi, A; Nicol, MR; Rizk, ML; Sabato, PE; Savic, RM; Wesche, D; Zheng, JH, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Nicol, MR | 1 |
| Joshi, A | 1 |
| Rizk, ML | 1 |
| Sabato, PE | 1 |
| Savic, RM | 1 |
| Wesche, D | 1 |
| Zheng, JH | 1 |
| Cook, J | 1 |
| Zanati, SA | 1 |
| Locarnini, SA | 1 |
| Dowling, JP | 1 |
| Angus, PW | 1 |
| Dudley, FJ | 1 |
| Roberts, SK | 1 |
| Neri, S | 1 |
| Pulvirenti, D | 1 |
| Patamia, I | 1 |
| Zoccolo, A | 1 |
| Castellino, P | 1 |
1 review available for chloroquine and Liver Failure
| Article | Year |
|---|---|
Pharmacokinetics and Pharmacological Properties of Chloroquine and Hydroxychloroquine in the Context of COVID-19 Infection.
Topics: Age Factors; Aging; Antiviral Agents; Chloroquine; Clinical Trials, Phase II as Topic; Clinical Tria | 2020 |
2 other studies available for chloroquine and Liver Failure
| Article | Year |
|---|---|
Hepatic failure due to fibrosing cholestatic hepatitis in a patient with pre-surface mutant hepatitis B virus and mixed connective tissue disease treated with prednisolone and chloroquine.
Topics: Adult; Chloroquine; Cholestasis; Fatal Outcome; Female; Hepatitis B; Hepatitis B Surface Antigens; H | 2004 |
Acute renal failure in Plasmodium malariae infection.
Topics: Acute Kidney Injury; Adult; Animals; Antimalarials; Chloroquine; Female; Humans; Liver Failure; Mala | 2008 |