chloroquine has been researched along with ATLL in 1 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adult T-cell leukemia/lymphoma (ATLL) originates from human T-cell leukemia virus type 1 (HTLV-1) infection due to the activation of the nuclear factor-κB (NF-κB) signaling pathway to maintain proliferation and survival." | 1.62 | Antitumor effects of chloroquine/hydroxychloroquine mediated by inhibition of the NF-κB signaling pathway through abrogation of autophagic p47 degradation in adult T-cell leukemia/lymphoma cells. ( Chilmi, S; Fauzi, YR; Ichikawa, T; Morishita, K; Nakahata, S; Nakamura, T; Nueangphuet, P; Shimoda, K; Yamaguchi, R, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fauzi, YR | 1 |
| Nakahata, S | 1 |
| Chilmi, S | 1 |
| Ichikawa, T | 1 |
| Nueangphuet, P | 1 |
| Yamaguchi, R | 1 |
| Nakamura, T | 1 |
| Shimoda, K | 1 |
| Morishita, K | 1 |
1 other study available for chloroquine and ATLL
| Article | Year |
|---|---|
Antitumor effects of chloroquine/hydroxychloroquine mediated by inhibition of the NF-κB signaling pathway through abrogation of autophagic p47 degradation in adult T-cell leukemia/lymphoma cells.
Topics: Animals; Apoptosis; Autophagy; Cell Line, Tumor; Chloroquine; Gene Expression Regulation, Leukemic; | 2021 |