chloroquine has been researched along with Leukemia, T-Cell in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Leukemia, T-Cell: A malignant disease of the T-LYMPHOCYTES in the bone marrow, thymus, and/or blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| " When HSB-2 T lymphoma cells were mixed with normal human bone marrow and incubated with 3A1-PAP and 100 microM chloroquine, approximately 3 logs of clonogenic T cells could be eliminated from a 20-fold excess of bone marrow." | 3.68 | Elimination of malignant clonogenic T cells from human bone marrow using chemoimmunoseparation with 2'-deoxycoformycin, deoxyadenosine and an immunotoxin. ( Haleen, A; Haynes, BF; Houston, LL; Kurtzberg, J; Montgomery, RB; Olsen, GA; Peters, WP; Ramakrishnan, S; Rhinehardt-Clark, A; Smith, CA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chavalitshewinkoon, P | 1 |
| Wilairat, P | 1 |
| Gamage, S | 1 |
| Denny, W | 1 |
| Figgitt, D | 1 |
| Ralph, R | 1 |
| Montgomery, RB | 1 |
| Kurtzberg, J | 1 |
| Rhinehardt-Clark, A | 1 |
| Haleen, A | 1 |
| Ramakrishnan, S | 1 |
| Olsen, GA | 1 |
| Peters, WP | 1 |
| Smith, CA | 1 |
| Haynes, BF | 1 |
| Houston, LL | 1 |
2 other studies available for chloroquine and Leukemia, T-Cell
| Article | Year |
|---|---|
Structure-activity relationships and modes of action of 9-anilinoacridines against chloroquine-resistant Plasmodium falciparum in vitro.
Topics: Amsacrine; Animals; Antimalarials; Cell Line; Chloroquine; Drug Resistance, Microbial; Humans; Leuke | 1993 |
Elimination of malignant clonogenic T cells from human bone marrow using chemoimmunoseparation with 2'-deoxycoformycin, deoxyadenosine and an immunotoxin.
Topics: Antiviral Agents; Bone Marrow; Cell Line; Cell Separation; Chloroquine; Deoxyadenosines; Hematopoiet | 1990 |