chloroquine has been researched along with Leucocythaemia in 13 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Verapamil pretreatment of cytoplasts from resistant cells revealed the subcellular DNP-sensitive uptake present in parental cytoplasts." | 5.28 | Energy-dependent accumulation of daunorubicin into subcellular compartments of human leukemia cells and cytoplasts. ( Daniel, JC; Lecerf, JM; Levy, SB; Slapak, CA, 1992) |
| "Verapamil pretreatment of cytoplasts from resistant cells revealed the subcellular DNP-sensitive uptake present in parental cytoplasts." | 1.28 | Energy-dependent accumulation of daunorubicin into subcellular compartments of human leukemia cells and cytoplasts. ( Daniel, JC; Lecerf, JM; Levy, SB; Slapak, CA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Palmeira dos Santos, C | 1 |
| Pereira, GJ | 1 |
| Barbosa, CM | 1 |
| Jurkiewicz, A | 1 |
| Smaili, SS | 1 |
| Bincoletto, C | 1 |
| Guo, S | 1 |
| Liang, Y | 1 |
| Murphy, SF | 1 |
| Huang, A | 1 |
| Shen, H | 1 |
| Kelly, DF | 1 |
| Sobrado, P | 1 |
| Sheng, Z | 1 |
| Lu, Y | 1 |
| Liu, XF | 1 |
| Liu, TR | 1 |
| Fan, RF | 1 |
| Xu, YC | 1 |
| Zhang, XZ | 1 |
| Liu, LL | 1 |
| HIRAKI, K | 1 |
| KIMURA, I | 1 |
| Sasaki, R | 1 |
| Slapak, CA | 1 |
| Lecerf, JM | 1 |
| Daniel, JC | 1 |
| Levy, SB | 1 |
| Beck, WT | 4 |
| Cirtain, MC | 2 |
| Danks, MK | 1 |
| Felsted, RL | 2 |
| Safa, AR | 2 |
| Wolverton, JS | 1 |
| Suttle, DP | 1 |
| Trent, JM | 1 |
| Glover, CJ | 1 |
| Zamora, JM | 2 |
| Pearce, HL | 1 |
| Calabro, JJ | 1 |
| Katz, RM | 1 |
| Maltz, BA | 1 |
| Tanneberger, S | 1 |
| Bacigalupo, G | 1 |
| Ota, K | 1 |
3 reviews available for chloroquine and Leucocythaemia
| Article | Year |
|---|---|
[Various factors determining direction of differentiation in leukemic cells].
Topics: Acetamides; Animals; Antineoplastic Agents; Basophils; Carcinogens; Cell Differentiation; Chloroquin | 1996 |
A critical reappraisal of juvenile rheumatoid arthritis.
Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine | 1971 |
Multiple combination therapy in cancer chemotherapy in Japan.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chloroquine; Cyclophosphamide; Cytarabine; Drug | 1969 |
10 other studies available for chloroquine and Leucocythaemia
| Article | Year |
|---|---|
Comparative study of autophagy inhibition by 3MA and CQ on Cytarabine‑induced death of leukaemia cells.
Topics: Adenine; Antimalarials; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protoc | 2014 |
A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications.
Topics: Animals; Autophagy; Cell Survival; Chloroquine; Dactinomycin; Endosomes; Fluorescent Dyes; Gene Expr | 2015 |
Celecoxib exerts antitumor effects in HL-60 acute leukemia cells and inhibits autophagy by affecting lysosome function.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Celecoxib; Cell Proliferation; Chloroquine; HL-60 Cells | 2016 |
STUDIES ON THE TREATMENT OF MALIGNANT TUMORS WITH FIBROBLAST-INHIBITING AGENT. IV. EFFECTS OF CHLOROQUINE ON MALIGNANT LYMPHOMAS.
Topics: Chloroquine; Fibroblasts; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Lymphocytes; Lympho | 1964 |
Energy-dependent accumulation of daunorubicin into subcellular compartments of human leukemia cells and cytoplasts.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Compartmentation; Chloroquine; | 1992 |
Pharmacological, molecular, and cytogenetic analysis of "atypical" multidrug-resistant human leukemic cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloroquine; Chromosome Banding; Chromosome | 1987 |
Effects of indole alkaloids on multidrug resistance and labeling of P-glycoprotein by a photoaffinity analog of vinblastine.
Topics: Affinity Labels; Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Su | 1988 |
Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Chemical Phenomena; Chemistry, Physic | 1988 |
Chloroquine enhancement of anticancer drug cytotoxicity in multiple drug resistant human leukemic cells.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Count; Cells, Cultured; Chloroquine; Drug R | 1986 |
[On the value of chloroquine in the treatment of malignant tumor diseases].
Topics: Adenocarcinoma, Scirrhous; Adult; Aged; Animals; Breast Neoplasms; Bronchial Neoplasms; Carcinoma, E | 1967 |