chloroquine has been researched along with Leprosy in 20 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty three leprosy patients in reaction were treated with a combination of Metronidazole--Diethyl carbamazine citrate--Chloroquin which was reinforced either with prednisolone and/or Clofazimine in some, depending on the clinical state." | 3.66 | Multi-drug treatment for reactions in leprosy. ( Razack, EM; Zahra, A, 1981) |
| "Mean intraocular pressure was 12 mmHg (standard deviation, 4." | 1.35 | Ocular manifestation in treated multibacillary Hansen's disease. ( Muliyil, J; Parikh, R; Parikh, S; Thomas, R; Thomas, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (75.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Parikh, R | 1 |
| Thomas, S | 2 |
| Muliyil, J | 2 |
| Parikh, S | 1 |
| Thomas, R | 2 |
| JOB, CK | 1 |
| ZIEKUR, U | 1 |
| RAMANUJAM, K | 1 |
| RAMU, G | 1 |
| Onyango-Ogony, PJ | 1 |
| Razack, EM | 1 |
| Zahra, A | 1 |
| Birdi, TJ | 1 |
| D'Souza, S | 1 |
| Antia, NH | 1 |
| Trautman, JR | 1 |
| Bastien, P | 1 |
| Pfaltzgraff, RE | 1 |
| Sehgal, VN | 1 |
| Sharma, V | 1 |
| Sharma, VK | 1 |
| Lal, S | 1 |
| Gupta, AK | 1 |
| Elslager, EF | 1 |
| Meyer-Rohn, J | 1 |
| Goerttler, E | 1 |
| Karat, AB | 1 |
| Thomas, G | 1 |
| Rao, PS | 1 |
| Vischer, WA | 1 |
1 review available for chloroquine and Leprosy
| Article | Year |
|---|---|
New perspectives on the chemotherapy of malaria, filariasis, and leprosy.
Topics: Amodiaquine; Aniline Compounds; Antimalarials; Chloroquine; Cresols; Dapsone; Drug Resistance; Filar | 1974 |
1 trial available for chloroquine and Leprosy
| Article | Year |
|---|---|
Indomethacin in the management of erythema nodosum leprosum--a double-blind controlled trial.
Topics: Adolescent; Adult; Aspirin; Chloroquine; Clinical Trials as Topic; Erythema Nodosum; Humans; Indomet | 1969 |
18 other studies available for chloroquine and Leprosy
| Article | Year |
|---|---|
Ocular manifestation in treated multibacillary Hansen's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blindness; Cataract; Child; Chloroquine; Corneal Disease | 2009 |
Prevalence of glaucoma in treated multibacillary Hansen disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Chloroquine; Female; Glaucoma, Angle-Closure; Gla | 2003 |
Treatment of lepra reaction with chloroquine.
Topics: Chloroquine; Humans; Leprosy | 1960 |
[THERAPEUTIC EXPERIENCES WITH RESOCHIN AND RESOCHIN-CONTAINING PREPARATIONS IN DERMATOLOGICAL PATIENTS].
Topics: Carcinoma, Squamous Cell; Chloroquine; Drug Eruptions; Drug Therapy; Finger Injuries; Hematoma; Herp | 1964 |
A report on the use of chloroquine sulphate in lepra reaction.
Topics: Chloroquine; Humans; Leprosy | 1960 |
A preliminary trial of chloroquine diphosphate in lepra reaction.
Topics: Chloroquine; Humans; Leprosy | 1959 |
Preventable causes of blindness.
Topics: Adult; Africa, Eastern; Aged, 80 and over; Blindness; Child; Chloroquine; Humans; Leprosy; Malnutrit | 2006 |
The World Health Organisation North Fly clinico-epidemilogical pilot study.
Topics: Anemia; Child; Child, Preschool; Chloroquine; Cysticercosis; Elephantiasis; Epidemiologic Methods; F | 1980 |
Multi-drug treatment for reactions in leprosy.
Topics: Adolescent; Adult; Child; Chloroquine; Clofazimine; Diethylcarbamazine; Drug Therapy, Combination; F | 1981 |
Expression of mycobacterial antigens on murine dissociated Schwann cells infected with Mycobacterium leprae.
Topics: Animals; Antibodies, Bacterial; Antifungal Agents; Antigens, Bacterial; Antimalarials; Cell Membrane | 1997 |
Treatment of Hansen's disease.
Topics: Chloroquine; Clofazimine; Dapsone; Drug Resistance, Microbial; Erythema Nodosum; Humans; Leprosy; Pr | 1976 |
Public-health epidemiology in Vanuatu.
Topics: Adolescent; Anemia; Animals; Cardiovascular Diseases; Child; Child, Preschool; Chloroquine; Drug Res | 1990 |
The management of reaction in leprosy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Aspirin; Benzenesulfonates; Chloroquine | 1989 |
The effect of anti-reactional drugs on complement components in the type II, erythema nodosum leprosum, reaction.
Topics: Chloroquine; Clofazimine; Complement C3; Complement Factor B; Complement System Proteins; Erythema N | 1988 |
Lenticular deposits associated with chloroquine Keratopathy.
Topics: Cataract; Chloroquine; Corneal Opacity; Humans; Leprosy; Male; Middle Aged | 1974 |
[Progress in the therapy of skin and venereal diseases since the year 1945].
Topics: Anti-Bacterial Agents; Antitubercular Agents; Chloroquine; Humans; Leprosy; Lupus Erythematosus, Sys | 1972 |
[Erythema elevatum diutinum with alopecic changes].
Topics: Adult; Alopecia; Capillaries; Chloroquine; Diagnosis, Differential; Erythema; Humans; Leprosy; Lupus | 1973 |
Antimicrobial activity of the leprostatic drug 3-(p-chloranilino)-10-(p-chlorphenyl-2,10-dihydro-2-(isopropylimino)-phenazine (G 30'320, B. 663).
Topics: Animals; Antitubercular Agents; Aspergillosis; Candidiasis; Chloroquine; Cricetinae; Disease Models, | 1970 |