Page last updated: 2024-10-24

chloroquine and Kwashiorkor

chloroquine has been researched along with Kwashiorkor in 8 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Kwashiorkor: A syndrome produced by severe protein deficiency, characterized by retarded growth, changes in skin and hair pigment, edema, and pathologic changes in the liver, including fatty infiltration, necrosis, and fibrosis. The word is a local name in Gold Coast, Africa, meaning displaced child. Although first reported from Africa, kwashiorkor is now known throughout the world, but mainly in the tropics and subtropics. It is considered to be related to marasmus. (From Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"The nutrition of a group of Nigerian children who received weekly chemoprophylaxis with chloroquine during their first one or two years of life was compared with the nutrition of a group of children exposed frequently to malaria."9.05Malaria chemoprophylaxis with chloroquine in young Nigerian children. III. Its effect on nutrition. ( Bradley, AK; Bradley-Moore, AM; Gilles, HM; Greenwood, BM; Kirkwood, BR, 1985)
"The single dose disposition of chloroquine was studied in five children with kwashiorkor and six normal control children after an oral dose of 10 mg kg-1 of chloroquine base."7.67Single dose disposition of chloroquine in kwashiorkor and normal children--evidence for decreased absorption in kwashiorkor. ( Alván, G; Dawodu, AH; Johnson, AO; Salako, LA; Walker, O, 1987)
"The binding of chloroquine to kwashiorkor and normal serum was investigated."7.65The binding of chloroquine to normal and Kwashiorkor serum. ( Buchanan, N; Van der Walt, LA, 1977)
"In a study of 40 children with kwashiorkor, serum albumin, transferrin, and immunoglobulin levels were measured."7.65Immunity, transferrin, and survival in kwashiorkor. ( Adcock, KJ; Adeshina, H; Akene, J; Cooke, AR; McFAarlane, H; Reddy, S, 1970)
"The nutrition of a group of Nigerian children who received weekly chemoprophylaxis with chloroquine during their first one or two years of life was compared with the nutrition of a group of children exposed frequently to malaria."5.05Malaria chemoprophylaxis with chloroquine in young Nigerian children. III. Its effect on nutrition. ( Bradley, AK; Bradley-Moore, AM; Gilles, HM; Greenwood, BM; Kirkwood, BR, 1985)
"In a study of 40 children with kwashiorkor, serum albumin, transferrin, and immunoglobulin levels were measured."3.65Immunity, transferrin, and survival in kwashiorkor. ( Adcock, KJ; Adeshina, H; Akene, J; Cooke, AR; McFAarlane, H; Reddy, S, 1970)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buchanan, N1
Van der Walt, LA1
Walker, O1
Dawodu, AH1
Salako, LA1
Alván, G1
Johnson, AO1
Bradley-Moore, AM1
Greenwood, BM1
Bradley, AK1
Kirkwood, BR1
Gilles, HM1
Reddy, S1
Adcock, KJ1
Adeshina, H1
Cooke, AR1
Akene, J1
McFAarlane, H1
Poskitt, EM1
Kingston, M1
Wharton, BA1
McChesney, EW1
MacWilliam, KM1

Trials

1 trial available for chloroquine and Kwashiorkor

ArticleYear
Malaria chemoprophylaxis with chloroquine in young Nigerian children. III. Its effect on nutrition.
    Annals of tropical medicine and parasitology, 1985, Volume: 79, Issue:6

    Topics: Anthropometry; Body Height; Body Weight; Child, Preschool; Chloroquine; Humans; Infant; Infant Nutri

1985

Other Studies

7 other studies available for chloroquine and Kwashiorkor

ArticleYear
The binding of chloroquine to normal and Kwashiorkor serum.
    The American journal of tropical medicine and hygiene, 1977, Volume: 26, Issue:5 Pt 1

    Topics: Alpha-Globulins; Beta-Globulins; Chloroquine; gamma-Globulins; Humans; Kwashiorkor; Serum Albumin; S

1977
Single dose disposition of chloroquine in kwashiorkor and normal children--evidence for decreased absorption in kwashiorkor.
    British journal of clinical pharmacology, 1987, Volume: 23, Issue:4

    Topics: Child, Preschool; Chloroquine; Humans; Intestinal Absorption; Kinetics; Kwashiorkor

1987
Immunity, transferrin, and survival in kwashiorkor.
    British medical journal, 1970, Oct-31, Volume: 4, Issue:5730

    Topics: Child, Preschool; Chloroquine; Diet Therapy; Dietary Proteins; Female; Folic Acid; gamma-Globulins;

1970
Clinical problems related to the use of drugs in malnutrition.
    The Proceedings of the Nutrition Society, 1974, Volume: 33, Issue:3

    Topics: Child; Child Nutritional Physiological Phenomena; Chloramphenicol; Chloroquine; Drug-Related Side Ef

1974
Electrolyte disturbances in Liberian children with kwashiorkor.
    The Journal of pediatrics, 1973, Volume: 83, Issue:5

    Topics: Alkalies; Alkalosis; Arteries; Blood; Calcium; Child; Child, Preschool; Chlorides; Chloroquine; Cult

1973
Chloroquine metabolism in kwashiorkor.
    Journal of tropical pediatrics (1967), 1970, Volume: 16, Issue:3

    Topics: Child; Chloroquine; Humans; Kwashiorkor; Malaria

1970
Serum haptoglobin values in 39 malnourished Uganda children.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1966, Volume: 60, Issue:3

    Topics: Adult; Anemia; Blood Chemical Analysis; Blood Protein Electrophoresis; Child, Preschool; Chloroquine

1966