Page last updated: 2024-10-24

chloroquine and Joint Pain

chloroquine has been researched along with Joint Pain in 7 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Research Excerpts

ExcerptRelevanceReference
"Post-chikungunya joint pain (arthritis or arthralgia) is a clinical concern in endemic regions as it may cause a debilitating illness sometimes years after the acute infection."2.82Treatment of chikungunya-associated joint pain: a systematic review of controlled clinical trials. ( Fernando, D; Herath, T; Rajapakse, S; Rodrigo, C; Wickramarachchi, U, 2022)
"The intensity of joint pain decreased in the active vs placebo group at the end of treatment, although these differences were not statistically significant."2.74Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial. ( Aguirre, V; Arriagada, S; Bertoglio, JC; Burgos, RA; Cáceres, DD; Calvo, M; Hancke, JL, 2009)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Rodrigo, C1
Herath, T1
Wickramarachchi, U1
Fernando, D1
Rajapakse, S1
Burgos, RA1
Hancke, JL1
Bertoglio, JC1
Aguirre, V1
Arriagada, S1
Calvo, M1
Cáceres, DD1
Burt, FJ1
Rolph, MS1
Rulli, NE1
Mahalingam, S1
Heise, MT1
Islam, MN1
Hossain, M1
Haq, SA1
Alam, MN1
Ten Klooster, PM1
Rasker, JJ1
Fernando, SD1
Wickremasinghe, AR1
Taubitz, W1
Cramer, JP1
Kapaun, A1
Pfeffer, M1
Drosten, C1
Dobler, G1
Burchard, GD1
Löscher, T1
Savarino, A1
Cauda, R1
Cassone, A1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Controlled, Randomized, Double-blind Clinical Trial, 24 Months Duration, to Compare the Efficacy, Safety and Tolerability of Andrographolide Versus Placebo in Patients With Progressive Forms of Multiple Sclerosis[NCT02273635]Phase 1/Phase 268 participants (Anticipated)Interventional2014-09-30Recruiting
Clinical Phase II Pilot Study of the Efficacy of FANG(30) to Treat Active Rheumatoid Arthritis in Adult Patients[NCT00749645]Phase 260 participants (Actual)Interventional2006-10-31Completed
Randomized, Comparative, Double Blind Controlled Phase II Clinical Trial, to Evaluate the Efficacy of ApE in Patients With Multiple Sclerosis (MS).[NCT02280876]Phase 1/Phase 230 participants (Actual)Interventional2012-01-31Completed
Study of the Prognostic Value of Musculoskeletal Ultrasound in Adults With Chikungunya[NCT02281123]200 participants (Anticipated)Observational2014-07-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for chloroquine and Joint Pain

ArticleYear
Treatment of chikungunya-associated joint pain: a systematic review of controlled clinical trials.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2022, 10-02, Volume: 116, Issue:10

    Topics: Anti-Inflammatory Agents; Arthralgia; Chikungunya Fever; Chloroquine; Humans; Hydroxychloroquine; Me

2022
Chikungunya: a re-emerging virus.
    Lancet (London, England), 2012, Feb-18, Volume: 379, Issue:9816

    Topics: Aedes; Africa; Alphavirus Infections; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies,

2012

Trials

2 trials available for chloroquine and Joint Pain

ArticleYear
Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial.
    Clinical rheumatology, 2009, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Aged; Andrographis; Arsenicals; Arthralgia; Arthritis, Rheumatoid; Chloroquine; D

2009
Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial.
    Clinical rheumatology, 2009, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Aged; Andrographis; Arsenicals; Arthralgia; Arthritis, Rheumatoid; Chloroquine; D

2009
Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial.
    Clinical rheumatology, 2009, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Aged; Andrographis; Arsenicals; Arthralgia; Arthritis, Rheumatoid; Chloroquine; D

2009
Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial.
    Clinical rheumatology, 2009, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Aged; Andrographis; Arsenicals; Arthralgia; Arthritis, Rheumatoid; Chloroquine; D

2009
Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial.
    Clinical rheumatology, 2009, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Aged; Andrographis; Arsenicals; Arthralgia; Arthritis, Rheumatoid; Chloroquine; D

2009
Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial.
    Clinical rheumatology, 2009, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Aged; Andrographis; Arsenicals; Arthralgia; Arthritis, Rheumatoid; Chloroquine; D

2009
Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial.
    Clinical rheumatology, 2009, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Aged; Andrographis; Arsenicals; Arthralgia; Arthritis, Rheumatoid; Chloroquine; D

2009
Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial.
    Clinical rheumatology, 2009, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Aged; Andrographis; Arsenicals; Arthralgia; Arthritis, Rheumatoid; Chloroquine; D

2009
Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms: a prospective randomized placebo-controlled trial.
    Clinical rheumatology, 2009, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Aged; Andrographis; Arsenicals; Arthralgia; Arthritis, Rheumatoid; Chloroquine; D

2009
Efficacy and safety of methotrexate in articular and cutaneous manifestations of systemic lupus erythematosus.
    International journal of rheumatic diseases, 2012, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Arthralgia; Arthritis; Bangladesh; Blood Sedimentation; Chloroquine; Female; Huma

2012

Other Studies

3 other studies available for chloroquine and Joint Pain

ArticleYear
The clinical and epidemiological features of childhood malaria in a moderately endemic area of Sri Lanka.
    The Southeast Asian journal of tropical medicine and public health, 2002, Volume: 33, Issue:4

    Topics: Administration, Oral; Antimalarials; Arthralgia; Case-Control Studies; Child; Child Welfare; Child,

2002
Chikungunya fever in travelers: clinical presentation and course.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, Jul-01, Volume: 45, Issue:1

    Topics: Adolescent; Adult; Alphavirus Infections; Arthralgia; Chikungunya virus; Child; Chloroquine; Female;

2007
On the use of chloroquine for chikungunya.
    The Lancet. Infectious diseases, 2007, Volume: 7, Issue:10

    Topics: Alphavirus Infections; Antirheumatic Agents; Arthralgia; Chikungunya virus; Chloroquine; Humans; Tre

2007