chloroquine has been researched along with Ischemic Stroke in 1 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Ischemic Stroke: Stroke due to BRAIN ISCHEMIA resulting in interruption or reduction of blood flow to a part of the brain. When obstruction is due to a BLOOD CLOT formed within in a cerebral blood vessel it is a thrombotic stroke. When obstruction is formed elsewhere and moved to block a cerebral blood vessel (see CEREBRAL EMBOLISM) it is referred to as embolic stroke. Wake-up stroke refers to ischemic stroke occurring during sleep while cryptogenic stroke refers to ischemic stroke of unknown origin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, focal cerebral ischemia was induced by transient middle cerebral artery occlusion in mice." | 1.91 | URB597 exerts neuroprotective effects against transient brain ischemia injury in mice by regulating autophagic flux and necroptosis. ( Chen, L; Jin, X; Luo, D; Peng, L; Qiu, Y; Yang, L; Ye, W; Yuan, X; Zhao, Y; Zhou, L; Zhou, Y; Zhuo, R, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, X | 1 |
| Ye, W | 1 |
| Chen, L | 1 |
| Luo, D | 1 |
| Zhou, L | 1 |
| Qiu, Y | 1 |
| Zhuo, R | 1 |
| Zhao, Y | 1 |
| Peng, L | 1 |
| Yang, L | 1 |
| Jin, X | 1 |
| Zhou, Y | 1 |
1 other study available for chloroquine and Ischemic Stroke
| Article | Year |
|---|---|
URB597 exerts neuroprotective effects against transient brain ischemia injury in mice by regulating autophagic flux and necroptosis.
Topics: Animals; Autophagy; Brain Injuries; Brain Ischemia; Chloroquine; Infarction, Middle Cerebral Artery; | 2023 |