chloroquine has been researched along with Insulinoma in 3 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine treatment delayed the spontaneous onset of diabetes in NOD mice, coincident with the decreased activation of PLN DCs." | 1.36 | TLR9 blockade inhibits activation of diabetogenic CD8+ T cells and delays autoimmune diabetes. ( Dutz, JP; Finegood, D; Geng, X; Lee, AS; Santamaria, P; Shameli, A; Zhang, Y, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Y | 1 |
| Lee, AS | 1 |
| Shameli, A | 1 |
| Geng, X | 1 |
| Finegood, D | 1 |
| Santamaria, P | 1 |
| Dutz, JP | 1 |
| Göke, R | 1 |
| Richter, G | 1 |
| Göke, B | 1 |
| Trautmann, M | 1 |
| Arnold, R | 1 |
| Hutton, JC | 1 |
| Davidson, HW | 1 |
| Grimaldi, KA | 1 |
| Peshavaria, M | 1 |
3 other studies available for chloroquine and Insulinoma
| Article | Year |
|---|---|
TLR9 blockade inhibits activation of diabetogenic CD8+ T cells and delays autoimmune diabetes.
Topics: Animals; CD8-Positive T-Lymphocytes; Cell Differentiation; Chloroquine; Clone Cells; CpG Islands; Di | 2010 |
Internalization of glucagon-like peptide-1(7-36)amide in rat insulinoma cells.
Topics: Adenoma, Islet Cell; Animals; Chloroquine; Chromatography, High Pressure Liquid; Glucagon; Glucagon- | 1989 |
Biosynthesis of betagranin in pancreatic beta-cells. Identification of a chromogranin A-like precursor and its parallel processing with proinsulin.
Topics: Animals; Chemical Precipitation; Chloroquine; Chromogranin A; Chromogranins; Electrophoresis, Polyac | 1987 |