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chloroquine and Inflammatory Bowel Diseases

chloroquine has been researched along with Inflammatory Bowel Diseases in 4 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Inflammatory Bowel Diseases: Chronic, non-specific inflammation of the GASTROINTESTINAL TRACT. Etiology may be genetic or environmental. This term includes CROHN DISEASE and ULCERATIVE COLITIS.

Research Excerpts

ExcerptRelevanceReference
" Single-dose pharmacokinetic and biodistribution studies performed in the colitis model indicated negligible systemic absorption (p ≤ 0."1.48Pharmacokinetics and efficacy of orally administered polymeric chloroquine as macromolecular drug in the treatment of inflammatory bowel disease. ( Ahmad, R; Chen, Y; Chhonker, YS; Jaramillo, L; Kanvinde, S; Li, J; Murry, DJ; Oupický, D; Sheinin, Y; Singh, AB; Sleightholm, R; Tang, W; Yu, F, 2018)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, SL1
Shao, BZ1
Zhao, SB1
Chang, X1
Wang, P1
Miao, CY1
Li, ZS1
Bai, Y1
Kanvinde, S1
Chhonker, YS1
Ahmad, R1
Yu, F1
Sleightholm, R1
Tang, W1
Jaramillo, L1
Chen, Y1
Sheinin, Y1
Li, J1
Murry, DJ1
Singh, AB1
Oupický, D1
Nagar, J1
Ranade, S1
Kamath, V1
Singh, S1
Karunanithi, P1
Subramani, S1
Venkatesh, K1
Srivastava, R1
Dudhgaonkar, S1
Vikramadithyan, RK1
Burakoff, R1

Reviews

1 review available for chloroquine and Inflammatory Bowel Diseases

ArticleYear
Inflammatory bowel disease workshop. Vail, Colorado, March 22 and 23, 1998. Less commonly used therapies for IBD or treatments on the fringe.
    Inflammatory bowel diseases, 1998, Volume: 4, Issue:4

    Topics: Anti-Bacterial Agents; Chloroquine; Enteral Nutrition; Fatty Acids, Volatile; Female; Fish Oils; Hum

1998

Other Studies

3 other studies available for chloroquine and Inflammatory Bowel Diseases

ArticleYear
Intestinal autophagy links psychosocial stress with gut microbiota to promote inflammatory bowel disease.
    Cell death & disease, 2019, 09-30, Volume: 10, Issue:6

    Topics: Adult; Animals; Autophagy; Autophagy-Related Proteins; Cathepsin D; Chloroquine; Colon; Corticotropi

2019
Pharmacokinetics and efficacy of orally administered polymeric chloroquine as macromolecular drug in the treatment of inflammatory bowel disease.
    Acta biomaterialia, 2018, Volume: 82

    Topics: Administration, Oral; Animals; Chloroquine; Citrobacter rodentium; Cytokines; Disease Models, Animal

2018
Therapeutic potential of chloroquine in a murine model of inflammatory bowel disease.
    International immunopharmacology, 2014, Volume: 21, Issue:2

    Topics: Animals; Body Weight; Cell Proliferation; Chloroquine; Colitis; Colon; Cytokines; Disease Models, An

2014