chloroquine has been researched along with Hypotension in 3 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although empirical regimens of parenteral chloroquine have been used extensively to treat severe malaria for 40 years, recent recommendations state that parenteral chloroquine should no longer be used because of potential toxicity." | 7.67 | Chloroquine treatment of severe malaria in children. Pharmacokinetics, toxicity, and new dosage recommendations. ( Berry, C; Brown, J; Churchill, FC; Greenwood, BM; Miller, KD; White, NJ; Williams, SB, 1988) |
| "Although empirical regimens of parenteral chloroquine have been used extensively to treat severe malaria for 40 years, recent recommendations state that parenteral chloroquine should no longer be used because of potential toxicity." | 3.67 | Chloroquine treatment of severe malaria in children. Pharmacokinetics, toxicity, and new dosage recommendations. ( Berry, C; Brown, J; Churchill, FC; Greenwood, BM; Miller, KD; White, NJ; Williams, SB, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ARORA, RB | 1 |
| LAL, A | 1 |
| Belghiti, J | 1 |
| Belghiti, D | 1 |
| Amedome, A | 1 |
| Durand, H | 1 |
| White, NJ | 1 |
| Miller, KD | 1 |
| Churchill, FC | 1 |
| Berry, C | 1 |
| Brown, J | 1 |
| Williams, SB | 1 |
| Greenwood, BM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi Center Randomized Open Label Trial on the Safety and Efficacy of Chloroquine for the Treatment of Hospitalized Adults With Laboratory Confirmed SARS-CoV-2 Infection in Vietnam[NCT04328493] | Phase 2 | 10 participants (Actual) | Interventional | 2020-04-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for chloroquine and Hypotension
| Article | Year |
|---|---|
ANTIMALARIAL DRUGS ON THE AUTOMATICITY OF SINO-AURICULAR AND ATRIO-VENTRICULAR NODES.
Topics: Administration, Intravenous; Amodiaquine; Animals; Anti-Arrhythmia Agents; Antimalarials; Atrioventr | 1963 |
[Letter: Intoxication with chloroquine with cardiac disorders. Effect of isoprenaline].
Topics: Adolescent; Chloroquine; Heart Diseases; Humans; Hypotension; Isoproterenol; Male; Shock, Cardiogeni | 1975 |
Chloroquine treatment of severe malaria in children. Pharmacokinetics, toxicity, and new dosage recommendations.
Topics: Animals; Child; Child, Preschool; Chloroquine; Drug Administration Schedule; Humans; Hypotension; In | 1988 |