chloroquine has been researched along with Hypokalemia in 15 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neither diazepam nor other ligands for benzodiazepine binding sites protect against or attenuate chloroquine cardiotoxicity." | 3.96 | Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam. ( Hughes, DA, 2020) |
| "Large doses of chloroquine can cause poisoning." | 3.69 | Hypokalaemia related to acute chloroquine ingestion. ( Baud, FJ; Borron, SW; Clemessy, JL; Favier, C; Hantson, PE; Vicaut, E, 1995) |
| "Chloroquine is a derivative of 4-aminoquinoline, which is used in the malaria prophylaxis and treatment and the therapy of some connective tissue diseases." | 2.43 | [Acute chloroquine intoxication--rare, but always serious: case reports and literature review]. ( Ciszowski, K; Groszek, B; Kołodziej, J; Kłys, M; Winnik, L, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (53.33) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| TeBay, C | 1 |
| McArthur, JR | 1 |
| Mangala, M | 1 |
| Kerr, N | 1 |
| Heitmann, S | 1 |
| Perry, MD | 1 |
| Windley, MJ | 1 |
| Vandenberg, JI | 1 |
| Hill, AP | 1 |
| Hughes, DA | 1 |
| Yelve, K | 1 |
| Phatak, S | 1 |
| Patil, MA | 1 |
| Pazare, AR | 1 |
| Ciszowski, K | 1 |
| Winnik, L | 1 |
| Groszek, B | 1 |
| Kłys, M | 1 |
| Kołodziej, J | 1 |
| Angel, G | 1 |
| Guerre Berthelot, P | 1 |
| Rogier, C | 1 |
| Clemessy, JL | 1 |
| Favier, C | 1 |
| Borron, SW | 1 |
| Hantson, PE | 1 |
| Vicaut, E | 1 |
| Baud, FJ | 1 |
| Buchanan, N | 1 |
| Bird, JW | 1 |
| Hansen Kristiansen, JE | 1 |
| Mayer, K | 1 |
| Gastinne, H | 1 |
| Voultoury, JC | 1 |
| Villate, D | 1 |
| Venot, J | 1 |
| Brivet, F | 1 |
| Dormont, J | 1 |
| Jaeger, A | 1 |
| Sauder, P | 1 |
| Kopferschmitt, J | 1 |
| Flesch, F | 1 |
| Roelofs, RI | 1 |
| Engel, WK | 1 |
| Kingston, M | 1 |
2 reviews available for chloroquine and Hypokalemia
| Article | Year |
|---|---|
[Acute chloroquine intoxication--rare, but always serious: case reports and literature review].
Topics: Adolescent; Antimalarials; Chloroquine; Drug Overdose; Fatal Outcome; Female; Heart Arrest; Heart Co | 2005 |
Skeletal muscle lysosomes.
Topics: Animals; Centrifugation, Density Gradient; Chloroquine; Fasting; Glycogen Storage Disease Type II; G | 1975 |
13 other studies available for chloroquine and Hypokalemia
| Article | Year |
|---|---|
Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation.
Topics: Acidosis; Azithromycin; Chloroquine; COVID-19 Drug Treatment; Female; Humans; Hydroxychloroquine; Hy | 2022 |
Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam.
Topics: Animals; Arrhythmias, Cardiac; Benzodiazepinones; Cardiotoxicity; Chloroquine; Clonazepam; Coronavir | 2020 |
Syncope in a patient being treated for hepatic and intestinal amoebiasis.
Topics: Amebicides; Antiprotozoal Agents; Chloroquine; Dysentery, Amebic; Furans; Humans; Hypokalemia; Liver | 2012 |
Hypokalaemia related to acute chloroquine poisoning.
Topics: Acute Disease; Chloroquine; Humans; Hypokalemia; Poisoning; Potassium | 1995 |
Hypokalaemia related to acute chloroquine ingestion.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Cause of Death; Chloroquin | 1995 |
Hypokalaemia and acute chloroquine ingestion.
Topics: Antimalarials; Chloroquine; Humans; Hypokalemia; Paris; Poisoning | 1996 |
[Fatal chloroquine poisoning with severe hypokalemia].
Topics: Adult; Chloroquine; Female; Humans; Hypokalemia; Suicide | 1977 |
[Neurogenic symptoms for the early diagnosis of adverse drug effects].
Topics: Anti-Bacterial Agents; Anticoagulants; Basal Ganglia Diseases; Chloroquine; Cortisone; Depression; D | 1976 |
[Hypokalemia by transfer in acute chloroquine poisoning].
Topics: Adult; Biological Transport; Chloroquine; Humans; Hypokalemia; Male; Potassium | 1987 |
[Hypokalemia in chloroquine poisoning].
Topics: Chloroquine; Humans; Hypokalemia | 1987 |
[Hypokalemia in chloroquine poisoning].
Topics: Adult; Child; Child, Preschool; Chloroquine; Humans; Hypokalemia; Middle Aged | 1987 |
Myopathies associated with systemic diseases.
Topics: Alcoholism; Anti-Bacterial Agents; Chloroquine; Collagen Diseases; Endocrine System Diseases; Erythe | 1971 |
Electrolyte disturbances in Liberian children with kwashiorkor.
Topics: Alkalies; Alkalosis; Arteries; Blood; Calcium; Child; Child, Preschool; Chlorides; Chloroquine; Cult | 1973 |