chloroquine has been researched along with Histoplasmosis in 3 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Histoplasmosis: Infection resulting from exposure to the fungus HISTOPLASMA. It is worldwide in distribution and particularly common in the central and eastern states, especially areas around the Ohio and Mississippi River valleys.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with chloroquine for 10 d after a lethal inoculum of Hc protected six of nine mice; all control mice were dead by day 11 (P = 0." | 5.29 | Chloroquine induces human macrophage killing of Histoplasma capsulatum by limiting the availability of intracellular iron and is therapeutic in a murine model of histoplasmosis. ( Brunner, G; Deepe, GS; Gootee, L; Newman, SL, 1994) |
| "Treatment with chloroquine for 10 d after a lethal inoculum of Hc protected six of nine mice; all control mice were dead by day 11 (P = 0." | 1.29 | Chloroquine induces human macrophage killing of Histoplasma capsulatum by limiting the availability of intracellular iron and is therapeutic in a murine model of histoplasmosis. ( Brunner, G; Deepe, GS; Gootee, L; Newman, SL, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KAUFMAN, HE | 1 |
| Newman, SL | 1 |
| Gootee, L | 1 |
| Brunner, G | 1 |
| Deepe, GS | 1 |
| Weber, SM | 1 |
| Levitz, SM | 1 |
| Harrison, TS | 1 |
2 reviews available for chloroquine and Histoplasmosis
| Article | Year |
|---|---|
OCULAR INFLAMMATORY DISEASE.
Topics: Adrenal Cortex Hormones; Antigen-Antibody Reactions; Arthritis; Arthritis, Rheumatoid; Autoimmune Di | 1964 |
Chloroquine and the fungal phagosome.
Topics: Animals; Antifungal Agents; Chloroquine; Cryptococcosis; Cryptococcus neoformans; Histoplasma; Histo | 2000 |
1 other study available for chloroquine and Histoplasmosis
| Article | Year |
|---|---|
Chloroquine induces human macrophage killing of Histoplasma capsulatum by limiting the availability of intracellular iron and is therapeutic in a murine model of histoplasmosis.
Topics: Animals; Cells, Cultured; Chloroquine; Deferoxamine; Ferric Compounds; Histoplasma; Histoplasmosis; | 1994 |