chloroquine has been researched along with Histomoniasis in 17 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, a new semi-synthetic berberine analogue, 5,6-didehydro-8,8-diethyl-13-oxodihydroberberine chloride (1), showed nanomolar level potency against in vitro models of leishmaniasis, malaria, and trypanosomiasis as well as activity in an in vivo visceral leishmaniasis model." | 3.77 | Potent antiprotozoal activity of a novel semi-synthetic berberine derivative. ( Anklin, C; Bahar, M; Deng, Y; Doskotch, RW; Drew, ME; Gil, RR; He, S; Kinghorn, AD; Navarro-Vázquez, A; Pandharkar, T; Werbovetz, KA; Zhu, X, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (64.71) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pagliero, RJ | 1 |
| Lusvarghi, S | 1 |
| Pierini, AB | 1 |
| Brun, R | 2 |
| Mazzieri, MR | 1 |
| Bahar, M | 1 |
| Deng, Y | 1 |
| Zhu, X | 1 |
| He, S | 1 |
| Pandharkar, T | 1 |
| Drew, ME | 1 |
| Navarro-Vázquez, A | 1 |
| Anklin, C | 1 |
| Gil, RR | 1 |
| Doskotch, RW | 1 |
| Werbovetz, KA | 1 |
| Kinghorn, AD | 1 |
| Bouchikhi, F | 1 |
| Anizon, F | 1 |
| Moreau, P | 1 |
| Dürüst, Y | 1 |
| Karakuş, H | 1 |
| Kaiser, M | 1 |
| Tasdemir, D | 1 |
| Sykes, ML | 1 |
| Avery, VM | 1 |
| SWARTZWELDER, JC | 1 |
| PAPERMASTER, TC | 1 |
| FORBES, LS | 1 |
| Demkin, GP | 1 |
| von Sonnenburg, F | 1 |
| Prüfer, L | 1 |
| Cadi Soussi, M | 1 |
| Safi, L | 1 |
| Goldsmid, JM | 1 |
| Cook, GC | 1 |
| Most, H | 1 |
| Schüppel, H | 1 |
| Kühne, I | 1 |
| Ishchenko, GD | 1 |
| Fink, E | 1 |
| Nickel, P | 1 |
| Dann, O | 1 |
| Duĭsheev, AD | 1 |
3 reviews available for chloroquine and Histomoniasis
| Article | Year |
|---|---|
Approaches to protozoan drug discovery: phenotypic screening.
Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; P | 2013 |
[Progress in immunodiagnosis and chemotherapy of protozoan infections].
Topics: Amebiasis; Animals; Antibodies; Babesiosis; Chloroquine; Drug Resistance, Microbial; Giardiasis; Hum | 1983 |
Drug therapy. Treatment of common parasitic infections of man encountered in the United States. 2.
Topics: Amebiasis; Amebicides; Anthelmintics; Antimalarials; Antimony; Benzenesulfonates; Chloroquine; Clono | 1972 |
14 other studies available for chloroquine and Histomoniasis
| Article | Year |
|---|---|
Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines.
Topics: Animals; Antiprotozoal Agents; Cell Line; Humans; Leishmania donovani; Models, Molecular; Parasitic | 2010 |
Potent antiprotozoal activity of a novel semi-synthetic berberine derivative.
Topics: Animals; Antiprotozoal Agents; Berberine; Chlorocebus aethiops; Disease Models, Animal; Inhibitory C | 2011 |
Biological evaluation of glycosyl-isoindigo derivatives against the pathogenic agents of tropical diseases (malaria, Chagas disease, leishmaniasis and human African trypanosomiasis).
Topics: Animals; Antiprotozoal Agents; Drug Evaluation, Preclinical; Humans; Protozoan Infections | 2011 |
Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3]triazoles.
Topics: Animals; Antiprotozoal Agents; Cell Line; Eukaryota; Inhibitory Concentration 50; Magnetic Resonance | 2012 |
The effect of aralen on Giardia lambia infections in children.
Topics: Child; Chloroquine; Giardia; Giardiasis; Humans; Protozoan Infections | 1947 |
THE EFFECT OF CERTAIN SUBSTANCES AGAINST ECHINOCOCCUS GRANULOSUS AND TAENIA HYDATIGENA INFECTIONS IN DOGS.
Topics: Animals; Anthelmintics; Benzimidazoles; Chloroquine; Dithiazanine; Dog Diseases; Dogs; Echinococcosi | 1964 |
[The prevention and treatment of typhlohepatitis in turkeys].
Topics: Animals; Antiprotozoal Agents; Chloroquine; Phenothiazines; Protozoan Infections; Turkeys | 1966 |
[Contramibial. Importance in amebiasis and other protozoosis].
Topics: Adolescent; Adult; Amebiasis; Amebicides; Child; Chloroquine; Drug Combinations; Entamoebiasis; Fema | 1980 |
Imported parasitic infections in Tasmania.
Topics: Africa, Northern; Ancylostomiasis; Australia; Chloroquine; Helminthiasis; Humans; Intestinal Disease | 1979 |
Use of antiprotozoan and anthelmintic drugs during pregnancy: side-effects and contra-indications.
Topics: Abnormalities, Drug-Induced; Anthelmintics; Antimalarials; Antiprotozoal Agents; Chloroquine; Contra | 1992 |
[Hexamitiasis in two hen turkey flocks].
Topics: Animals; Antiprotozoal Agents; Chloroquine; Disease Outbreaks; Eukaryota; Female; Germany, East; Pou | 1971 |
[Test of quingamine in typhlohepatitis in turkeys].
Topics: Animals; Chloroquine; Protozoan Infections; Turkeys | 1969 |
[New 6-aminoquinolines with antimalarial activity. Test results on schizontocidal and causalprophylactic effects in rodent- and avian malaria (Plasmodium vinckei, P. berghei and P. cathemerium)].
Topics: Amines; Animals; Antimalarials; Canaries; Chloroquine; Drug Resistance, Microbial; Injections, Intra | 1970 |
[The use of chloroquine diphosphate in hemosporidiosis].
Topics: Animals; Cattle; Cattle Diseases; Chloroquine; Hematologic Diseases; Injections, Intramuscular; Prot | 1967 |