chloroquine has been researched along with Hepatocellular Carcinoma in 55 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study aimed to evaluate chloroquine's (CQ) ability to trigger TRAIL/TRAILR2 apoptotic pathway in thioacetamide (TAA)-induced hepatocellular carcinoma (HCC) either alone or in combination with doxorubicin (DOX)." | 7.88 | Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model. ( Eissa, LA; El Gayar, AM; El-Karef, A; El-Mesery, M; Helmy, SA, 2018) |
| "To investigate the effect of chloroquine in inducing apoptosis of human hepatocellular carcinoma cells and explore the possible mechanism." | 7.88 | [Chloroquine induces apoptosis of human hepatocellular carcinoma cells in vitro by miR-26b-mediated regulation of Mcl-1]. ( Jiang, CC; Liu, H; Ma, LY; Sun, XJ; Wang, Y; Zhang, MX; Zhang, P, 2018) |
| " Here, we explored the impact of salvianolic acid B (Sal B), the major water-soluble compounds of Danshen, on apoptosis and autophagy of human hepatocellular carcinoma cells (HCC)." | 7.83 | AKT/mTOR signaling pathway is involved in salvianolic acid B-induced autophagy and apoptosis in hepatocellular carcinoma cells. ( Chen, G; Chen, P; Di, C; Gong, L; Shi, J; Wang, J; Xia, X; Xu, H; Zhang, W, 2016) |
| "Luteolin induced apoptosis in human liver cancer SMMC-7721 cells, partially via autophagy." | 5.46 | Luteolin Promotes Cell Apoptosis by Inducing Autophagy in Hepatocellular Carcinoma. ( Cai, X; Cao, Z; Chai, D; Chen, H; Chu, F; Fang, W; Wen, Y; Zhang, H; Zhang, Y, 2017) |
| "Sorafenib treatment led to accumulation of autophagosomes as evidenced by conversion from LC3-I to LC3-II observed by immunoblot in Huh7, HLF and PLC/PRF/5 cells." | 5.38 | Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma. ( Fujita, N; Hayashi, N; Hikita, H; Hiramatsu, N; Hosui, A; Ishida, H; Kanto, T; Kodama, T; Miyagi, T; Shimizu, S; Takehara, T; Tatsumi, T; Tsunematsu, H; Yoshimori, T, 2012) |
| " MATERIAL AND METHODS SMMC-7721 cells (a hepatocellular carcinoma cell line) were treated with different concentrations of oleanolic acid (OA) plus autophagy inhibitor 3-methyladenine (3-MA) (3-MA+OA) or chloroquine (CQ) plus OA (CQ+OA)." | 3.96 | Effect of Oleanolic Acid on Apoptosis and Autophagy of SMMC-7721 Hepatoma Cells. ( Wu, X; Zeng, X; Zhou, W, 2020) |
| " This study aimed to evaluate chloroquine's (CQ) ability to trigger TRAIL/TRAILR2 apoptotic pathway in thioacetamide (TAA)-induced hepatocellular carcinoma (HCC) either alone or in combination with doxorubicin (DOX)." | 3.88 | Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model. ( Eissa, LA; El Gayar, AM; El-Karef, A; El-Mesery, M; Helmy, SA, 2018) |
| "To investigate the effect of chloroquine in inducing apoptosis of human hepatocellular carcinoma cells and explore the possible mechanism." | 3.88 | [Chloroquine induces apoptosis of human hepatocellular carcinoma cells in vitro by miR-26b-mediated regulation of Mcl-1]. ( Jiang, CC; Liu, H; Ma, LY; Sun, XJ; Wang, Y; Zhang, MX; Zhang, P, 2018) |
| " Here, we explored the impact of salvianolic acid B (Sal B), the major water-soluble compounds of Danshen, on apoptosis and autophagy of human hepatocellular carcinoma cells (HCC)." | 3.83 | AKT/mTOR signaling pathway is involved in salvianolic acid B-induced autophagy and apoptosis in hepatocellular carcinoma cells. ( Chen, G; Chen, P; Di, C; Gong, L; Shi, J; Wang, J; Xia, X; Xu, H; Zhang, W, 2016) |
| "The growth inhibition and autophagy of liver cancer cells were detected using acridine orange fluorescence staining, flow cytometry and transmission electron microscopy." | 1.48 | The biological role of autophagy in regulating and controlling the proliferation of liver cancer cells induced by bufalin. ( Li, Q; Qin, J; Sheng, X; Zhu, P, 2018) |
| "Luteolin induced apoptosis in human liver cancer SMMC-7721 cells, partially via autophagy." | 1.46 | Luteolin Promotes Cell Apoptosis by Inducing Autophagy in Hepatocellular Carcinoma. ( Cai, X; Cao, Z; Chai, D; Chen, H; Chu, F; Fang, W; Wen, Y; Zhang, H; Zhang, Y, 2017) |
| "Liver cancer is the second-most frequent cause of cancer death in the world and is highly treatment resistant." | 1.42 | Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer. ( Chen, P; Chu, Y; Dong, Z; Hoffman, RM; Hu, T; Jeong, LS; Jia, L; Jiang, Y; Li, C; Li, P; Liang, Y; Pan, Y; Qi, H; Wei, D; Yang, M; Zhang, P, 2015) |
| "Invasion of hepatocellular carcinoma (HCC) cells is a leading cause of intrahepatic dissemination and metastasis." | 1.39 | Autophagy promotes hepatocellular carcinoma cell invasion through activation of epithelial-mesenchymal transition. ( Guo, Y; Li, J; Shang, D; Song, Z; Wu, Y; Xiong, J; Yang, B; Zheng, Q; Zhou, Q, 2013) |
| "Sorafenib treatment led to accumulation of autophagosomes as evidenced by conversion from LC3-I to LC3-II observed by immunoblot in Huh7, HLF and PLC/PRF/5 cells." | 1.38 | Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma. ( Fujita, N; Hayashi, N; Hikita, H; Hiramatsu, N; Hosui, A; Ishida, H; Kanto, T; Kodama, T; Miyagi, T; Shimizu, S; Takehara, T; Tatsumi, T; Tsunematsu, H; Yoshimori, T, 2012) |
| "This phenomenon is specific for hepatoma cell lines or primarily cultured hepatocytes." | 1.32 | pH-dependent translocation of alpha-tocopherol transfer protein (alpha-TTP) between hepatic cytosol and late endosomes. ( Arai, H; Arita, M; Horiguchi, M; Inoue, K; Kaempf-Rotzoll, DE; Tsujimoto, M, 2003) |
| "Human hepatoma cells took up Hb-Hp in a receptor-mediated manner." | 1.28 | Expression of haptoglobin receptors in human hepatoma cells. ( Okuda, M; Taketani, S; Tokunaga, R, 1992) |
| "The Fu5AH rat hepatoma cell line accumulates cholesteryl ester (CE) upon incubation in medium supplemented with hyperlipemic serum or hyperlipemic serum lipoproteins." | 1.26 | Origin of fatty acids of cholesteryl ester accumulated by Fu5AH cells in culture. ( Rosen, JM; Rothblat, GH, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (20.00) | 18.7374 |
| 1990's | 13 (23.64) | 18.2507 |
| 2000's | 3 (5.45) | 29.6817 |
| 2010's | 19 (34.55) | 24.3611 |
| 2020's | 9 (16.36) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, F | 1 |
| Tautenhahn, HM | 1 |
| Dirsch, O | 1 |
| Dahmen, U | 1 |
| Kaur, R | 1 |
| Kanthaje, S | 1 |
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| Dhiman, RK | 1 |
| Chakraborti, A | 1 |
| Okubo, S | 1 |
| Ohta, T | 1 |
| Shoyama, Y | 1 |
| Uto, T | 1 |
| Zhou, W | 1 |
| Zeng, X | 1 |
| Wu, X | 2 |
| Morin, G | 1 |
| Pinel, K | 1 |
| Dias, K | 1 |
| Seiliez, I | 1 |
| Beaumatin, F | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
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| Muthuswamy, N | 1 |
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| Li, X | 11 |
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| Gao, XC | 1 |
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| Wang, C | 4 |
| Zhou, X | 2 |
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| Hou, J | 1 |
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| Gao, C | 2 |
| Pang, D | 1 |
| Lu, K | 1 |
| Ahmad, NH | 1 |
| Wang, L | 2 |
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| Zhuang, T | 1 |
| Tu, J | 1 |
| Zhao, Z | 1 |
| Qu, Y | 1 |
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| Wang, X | 5 |
| Lee, DF | 1 |
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| Wen, L | 1 |
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| Zhao, Q | 1 |
| Hu, W | 1 |
| Zhang, Y | 6 |
| Lu, J | 2 |
| Li, M | 1 |
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| Wu, W | 1 |
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| Xu, Z | 1 |
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| Ke, AW | 1 |
| Wang, XY | 1 |
| Song, K | 1 |
| Dai, Z | 1 |
| Shen, YH | 1 |
| Shimizu, S | 1 |
| Takehara, T | 1 |
| Hikita, H | 1 |
| Kodama, T | 1 |
| Tsunematsu, H | 1 |
| Miyagi, T | 1 |
| Hosui, A | 1 |
| Ishida, H | 1 |
| Tatsumi, T | 1 |
| Kanto, T | 1 |
| Hiramatsu, N | 1 |
| Fujita, N | 1 |
| Yoshimori, T | 1 |
| Hayashi, N | 1 |
| Liu, WR | 1 |
| Yanze, MF | 1 |
| Lee, WS | 1 |
| Poon, K | 1 |
| Piquette-Miller, M | 1 |
| Macgregor, RB | 1 |
| Horiguchi, M | 1 |
| Arita, M | 1 |
| Kaempf-Rotzoll, DE | 1 |
| Tsujimoto, M | 1 |
| Inoue, K | 1 |
| Arai, H | 1 |
| Thomas, HC | 1 |
| Bassendine, MF | 1 |
| Moriarity, DM | 1 |
| DiSorbo, DM | 1 |
| Litwack, G | 1 |
| Savage, CR | 1 |
| Schwartz, AL | 2 |
| Bolognesi, A | 1 |
| Fridovich, SE | 1 |
| Dashti, N | 3 |
| Wolfbauer, G | 3 |
| Koren, E | 1 |
| Knowles, B | 1 |
| Alaupovic, P | 2 |
| Shimada, A | 1 |
| Tamai, T | 1 |
| Oida, K | 1 |
| Takahashi, S | 1 |
| Suzuki, J | 1 |
| Nakai, T | 1 |
| Miyabo, S | 1 |
| Hajjar, KA | 1 |
| Reynolds, CM | 1 |
| Midoux, P | 3 |
| Mendes, C | 1 |
| Legrand, A | 1 |
| Raimond, J | 1 |
| Mayer, R | 1 |
| Monsigny, M | 3 |
| Roche, AC | 3 |
| Sakai, N | 1 |
| Yamashita, S | 1 |
| Ueyama, Y | 1 |
| Kawamoto, T | 1 |
| Nakamura, T | 1 |
| Funahashi, T | 1 |
| Kameda-Takemura, K | 1 |
| Kawata, S | 1 |
| Kubo, M | 1 |
| Tokunaga, K | 1 |
| Erbacher, P | 2 |
| Lenk, SE | 1 |
| Susan, PP | 1 |
| Hickson, I | 1 |
| Jasionowski, T | 1 |
| Dunn, WA | 1 |
| Charpentier, D | 1 |
| Tremblay, C | 1 |
| Rassart, E | 1 |
| Rhainds, D | 1 |
| Auger, A | 1 |
| Milne, RW | 1 |
| Brissette, L | 1 |
| Rosen, JM | 1 |
| Rothblat, GH | 1 |
| Florén, CH | 1 |
| Underhill, DM | 1 |
| Owensby, DA | 1 |
| Morton, PA | 1 |
| Okuda, M | 1 |
| Tokunaga, R | 1 |
| Taketani, S | 1 |
| Odum, L | 1 |
| Sathre, KA | 1 |
| Tsang, ML | 1 |
| Weatherbee, JA | 1 |
| Steer, CJ | 1 |
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| Jarett, L | 1 |
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3 reviews available for chloroquine and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Nrf2-p62 autophagy pathway and its response to oxidative stress in hepatocellular carcinoma.
Topics: Animals; Autophagy; Carcinoma, Hepatocellular; Chloroquine; Humans; Hydroxychloroquine; Liver Neopla | 2018 |
Immunological and anti-viral therapy of chronic hepatitis B virus infection.
Topics: Adjuvants, Immunologic; Antibody Formation; Antiviral Agents; Carcinoma, Hepatocellular; Chloroquine | 1980 |
1 trial available for chloroquine and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
52 other studies available for chloroquine and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Blocking autophagy with chloroquine aggravates lipid accumulation and reduces intracellular energy synthesis in hepatocellular carcinoma cells, both contributing to its anti-proliferative effect.
Topics: Adenosine Triphosphate; Autophagy; Autophagy-Related Proteins; Carcinoma, Hepatocellular; Cell Line, | 2022 |
miR-23b-3p Modulating Cytoprotective Autophagy and Glutamine Addiction in Sorafenib Resistant HepG2, a Hepatocellular Carcinoma Cell Line.
Topics: Autophagy; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Gene Expression Regulation, Neoplastic | 2022 |
Arctigenin suppresses cell proliferation via autophagy inhibition in hepatocellular carcinoma cells.
Topics: Adenine; Apoptosis; Apoptosis Regulatory Proteins; Arctium; Autophagy; Carcinoma, Hepatocellular; Ce | 2020 |
Effect of Oleanolic Acid on Apoptosis and Autophagy of SMMC-7721 Hepatoma Cells.
Topics: Adenine; Adenosine Triphosphate; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; | 2020 |
RTH-149 Cell Line, a Useful Tool to Decipher Molecular Mechanisms Related to Fish Nutrition.
Topics: Amino Acids; Animals; Aquaculture; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Chloroqui | 2020 |
BCAT1 decreases the sensitivity of cancer cells to cisplatin by regulating mTOR-mediated autophagy via branched-chain amino acid metabolism.
Topics: Amino Acids, Branched-Chain; Animals; Antineoplastic Agents; Autophagy; Carcinoma, Hepatocellular; C | 2021 |
Methyl gallate, gallic acid-derived compound, inhibit cell proliferation through increasing ROS production and apoptosis in hepatocellular carcinoma cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Carcinoma, Hepatocell | 2021 |
HSF1 upregulates ATG4B expression and enhances epirubicin-induced protective autophagy in hepatocellular carcinoma cells.
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Autophagy; Autophagy-Related Proteins; Carcinoma, Hep | 2017 |
Luteolin Promotes Cell Apoptosis by Inducing Autophagy in Hepatocellular Carcinoma.
Topics: Apoptosis; Autophagosomes; Autophagy; Beclin-1; Blotting, Western; Carcinoma, Hepatocellular; Caspas | 2017 |
Chloroquine upregulates TRAIL/TRAILR2 expression and potentiates doxorubicin anti-tumor activity in thioacetamide-induced hepatocellular carcinoma model.
Topics: Animals; Carcinoma, Hepatocellular; Caspases; Chloroquine; Doxorubicin; Gene Expression Regulation; | 2018 |
The biological role of autophagy in regulating and controlling the proliferation of liver cancer cells induced by bufalin.
Topics: Adenine; Autophagy; Beclin-1; Bufanolides; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; | 2018 |
[Chloroquine induces apoptosis of human hepatocellular carcinoma cells in vitro by miR-26b-mediated regulation of Mcl-1].
Topics: Adenosine Triphosphate; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Chloroquine; Hep G | 2018 |
Targeting PARP and autophagy evoked synergistic lethality in hepatocellular carcinoma.
Topics: Animals; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Proliferation; Chloroquine; Drug Syne | 2020 |
Paradoxical role of autophagy in the dysplastic and tumor-forming stages of hepatocarcinoma development in rats.
Topics: Animals; Antioxidants; Autophagy; Carcinoma, Hepatocellular; Cell Proliferation; Cell Transformation | 2013 |
Autophagy promotes hepatocellular carcinoma cell invasion through activation of epithelial-mesenchymal transition.
Topics: Autophagy; Autophagy-Related Protein 7; Autophagy-Related Proteins; Carcinoma, Hepatocellular; Cell | 2013 |
Blocking autophagic flux enhances matrine-induced apoptosis in human hepatoma cells.
Topics: Adaptor Proteins, Signal Transducing; Alkaloids; Apoptosis; Apoptosis Regulatory Proteins; Autophagy | 2013 |
Effect of toll-like receptor 7 and 9 targeted therapy to prevent the development of hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Case-Control Studies; Cell Proliferation; Chloroquine; DNA; Hep | 2015 |
Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells.
Topics: Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Chloroquine; Extracellular Signal-Regulated | 2015 |
Regulation of MET receptor tyrosine kinase signaling by suppressor of cytokine signaling 1 in hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chlorocebus aethiops; Chlo | 2015 |
Synergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer.
Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Autophagy; Carcinoma, Hepatocellular; Cell Lin | 2015 |
Chloroquine inhibits hepatocellular carcinoma cell growth in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor; | 2016 |
Polyphyllin I induced-apoptosis is enhanced by inhibition of autophagy in human hepatocellular carcinoma cells.
Topics: Apoptosis; Autophagy; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Cell Proliferation; Chl | 2015 |
AKT/mTOR signaling pathway is involved in salvianolic acid B-induced autophagy and apoptosis in hepatocellular carcinoma cells.
Topics: Adenine; Antineoplastic Agents; Apoptosis; Autophagy; Beclin-1; Benzofurans; Carcinoma, Hepatocellul | 2016 |
Autophagy activation in hepatocellular carcinoma contributes to the tolerance of oxaliplatin via reactive oxygen species modulation.
Topics: Animals; Antimalarials; Antineoplastic Agents; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumo | 2011 |
Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Autophag | 2012 |
Proteasome inhibitor interacts synergistically with autophagy inhibitor to suppress proliferation and induce apoptosis in hepatocellular carcinoma.
Topics: Adenine; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Pro | 2012 |
Cellular uptake and metabolism of DNA frayed wires.
Topics: Adenosine Triphosphate; Binding, Competitive; Carcinoma, Hepatocellular; Cell Nucleus; Cell Survival | 2003 |
pH-dependent translocation of alpha-tocopherol transfer protein (alpha-TTP) between hepatic cytosol and late endosomes.
Topics: Amino Acid Sequence; Androstadienes; Animals; Biological Transport; Brefeldin A; Carcinoma, Hepatoce | 2003 |
Epidermal growth factor stimulation of ornithine decarboxylase activity in a human hepatoma cell line.
Topics: Ammonium Chloride; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Colchicine; Cy | 1981 |
Recycling of the asialoglycoprotein receptor and the effect of lysosomotropic amines in hepatoma cells.
Topics: Asialoglycoprotein Receptor; Asialoglycoproteins; Carcinoma, Hepatocellular; Cell Line; Cell Membran | 1984 |
Catabolism of human low density lipoproteins by human hepatoma cell line HepG2.
Topics: Binding, Competitive; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Colchicine; Humans; Lipopro | 1984 |
Increase in neutral cholesteryl ester hydrolase activity produced by extralysosomal hydrolysis of high-density lipoprotein cholesteryl esters in rat hepatoma cells (H-35).
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Cholesterol; Cholesterol Esters; Cyclohe | 1994 |
alpha-Fucose-mediated binding and degradation of tissue-type plasminogen activator by HepG2 cells.
Topics: Ammonium Chloride; Azides; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Dose-Response Relation | 1994 |
Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells.
Topics: Amino Acid Sequence; Carcinoma, Hepatocellular; Chloroquine; Fluorescein; Fluoresceins; Glycosylatio | 1993 |
Extralysosomal degradation of high-density lipoproteins in a human hepatoma cell line, Mahlavu.
Topics: Carcinoma, Hepatocellular; Cell Line; Chloroquine; Cholesterol Esters; Fibroblasts; Humans; Iodine R | 1993 |
Putative role of chloroquine in gene transfer into a human hepatoma cell line by DNA/lactosylated polylysine complexes.
Topics: Carcinoma, Hepatocellular; Chloroquine; Culture Media; DNA; Dose-Response Relationship, Drug; Endocy | 1996 |
The reduction of the positive charges of polylysine by partial gluconoylation increases the transfection efficiency of polylysine/DNA complexes.
Topics: Acylation; Amino Acid Sequence; Carcinoma, Hepatocellular; Chloroquine; DNA, Recombinant; Gluconates | 1997 |
Ubiquitinated aldolase B accumulates during starvation-induced lysosomal proteolysis.
Topics: Adenine; Amino Acid Sequence; Amino Acids; Animals; Antimalarials; Blood Proteins; Carcinoma, Hepato | 1999 |
Low- and high-density lipoprotein metabolism in HepG2 cells expressing various levels of apolipoprotein E.
Topics: Apolipoproteins E; Carcinoma, Hepatocellular; Chloroquine; Cholesterol Esters; Cholesterol, HDL; Gen | 2000 |
Origin of fatty acids of cholesteryl ester accumulated by Fu5AH cells in culture.
Topics: Carcinoma, Hepatocellular; Cell Line; Chloroquine; Cholesterol; Cholesterol Esters; Culture Media; F | 1977 |
Polymyxin B enhances low density lipoprotein catabolism in hepatic and extrahepatic cells.
Topics: Animals; Calcium; Carcinoma, Hepatocellular; Cattle; Cells, Cultured; Chloroquine; Colchicine; Endot | 1992 |
Endocytosis and lysosomal delivery of tissue plasminogen activator-inhibitor 1 complexes in Hep G2 cells.
Topics: Ammonium Chloride; beta-N-Acetylhexosaminidases; Carcinoma, Hepatocellular; Chloroquine; Endocytosis | 1992 |
Expression of haptoglobin receptors in human hepatoma cells.
Topics: Biological Transport; Cadaverine; Carcinoma, Hepatocellular; Cells, Cultured; Chloroquine; Endocytos | 1992 |
Biosynthesis of inter-alpha-trypsin inhibitor and alpha 1-microglobulin in a human hepatoma cell line.
Topics: Alpha-Globulins; Carbohydrate Metabolism; Carbohydrates; Carcinoma, Hepatocellular; Chloroquine; Ele | 1992 |
Binding and internalization of transforming growth factor-beta 1 by human hepatoma cells: evidence for receptor recycling.
Topics: Binding, Competitive; Carcinoma, Hepatocellular; Chloroquine; Cycloheximide; Humans; Hydrogen-Ion Co | 1991 |
Partial characterization of mechanism of insulin accumulation in H35 hepatoma cell nuclei.
Topics: Adenosine Triphosphate; Biological Transport; Carcinoma, Hepatocellular; Cell Nucleus; Chloroquine; | 1990 |
Evidence for two independent pathways of insulin-receptor internalization in hepatocytes and hepatoma cells.
Topics: 2,4-Dinitrophenol; Animals; Biological Transport; Biotransformation; Carcinoma, Hepatocellular; Cell | 1988 |
Binding and degradation of human high-density lipoproteins by human hepatoma cell line HepG2.
Topics: Binding Sites; Carcinoma, Hepatocellular; Cell Line; Chemical Phenomena; Chemistry; Chloroquine; Cho | 1985 |
Studies on the binding and degradation of human very-low-density lipoproteins by human hepatoma cell line HepG2.
Topics: Apolipoproteins B; Apolipoproteins E; Binding, Competitive; Carcinoma, Hepatocellular; Cell Line; Ch | 1986 |
Effects of acidotropic compounds on the secretory pathway: inhibition of secretion and processing of the third and fourth components of complement.
Topics: Amantadine; Benzamidines; Carcinoma, Hepatocellular; Cell Line; Chloroquine; Complement C3; Compleme | 1986 |
Human plasma cholesteryl ester transfer protein enhances the transfer of cholesteryl ester from high density lipoproteins into cultured HepG2 cells.
Topics: Carcinoma, Hepatocellular; Carrier Proteins; Cell Line; Chloroquine; Cholesterol Ester Transfer Prot | 1987 |
On the effects of weak bases and monensin on sorting and processing of lysosomal enzymes in human cells.
Topics: Ammonium Chloride; Carcinoma, Hepatocellular; Cathepsin D; Cell Line; Chloroquine; Fibroblasts; Huma | 1987 |