chloroquine has been researched along with Hepatitis C in 6 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Hepatitis C: INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroquine (CQ) is an autophagy inhibitor that is clinically used to treat malaria." | 2.82 | New use of an old drug: chloroquine reduces viral and ALT levels in HCV non-responders (a randomized, triple-blind, placebo-controlled pilot trial). ( Azarpira, N; Coombs, KM; Fattahi, MR; Geramizadeh, B; Ghavami, S; Keyvani, H; Lankarani, KB; Peymani, P; Sabour, S; Yeganeh, B, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Merk, HF | 1 |
| Peymani, P | 1 |
| Yeganeh, B | 1 |
| Sabour, S | 1 |
| Geramizadeh, B | 1 |
| Fattahi, MR | 1 |
| Keyvani, H | 1 |
| Azarpira, N | 1 |
| Coombs, KM | 1 |
| Ghavami, S | 1 |
| Lankarani, KB | 1 |
| Zhang, Y | 1 |
| El-Far, M | 1 |
| Dupuy, FP | 1 |
| Abdel-Hakeem, MS | 1 |
| He, Z | 1 |
| Procopio, FA | 1 |
| Shi, Y | 1 |
| Haddad, EK | 1 |
| Ancuta, P | 1 |
| Sekaly, RP | 1 |
| Said, EA | 1 |
| Barbieri, L | 1 |
| Macrì, A | 1 |
| Lupia Palmieri, G | 1 |
| Aurizi, C | 1 |
| Biolcati, G | 1 |
| Ashfaq, UA | 1 |
| Javed, T | 1 |
| Rehman, S | 1 |
| Nawaz, Z | 1 |
| Riazuddin, S | 1 |
| Lee, CH | 1 |
| Yuen, MM | 1 |
| Chow, WS | 1 |
| Tso, AW | 1 |
| Yeung, CK | 1 |
| Chan, JC | 1 |
| Chau, CH | 1 |
| Lam, KS | 1 |
1 review available for chloroquine and Hepatitis C
| Article | Year |
|---|---|
[Porphyria cutanea tara].
Topics: Alcoholism; Causality; Chloroquine; Comorbidity; Germany; Hemochromatosis; Hepatitis C; Humans; Iron | 2016 |
1 trial available for chloroquine and Hepatitis C
| Article | Year |
|---|---|
New use of an old drug: chloroquine reduces viral and ALT levels in HCV non-responders (a randomized, triple-blind, placebo-controlled pilot trial).
Topics: Adult; Alanine Transaminase; Antiviral Agents; Chloroquine; Double-Blind Method; Female; Follow-Up S | 2016 |
4 other studies available for chloroquine and Hepatitis C
| Article | Year |
|---|---|
HCV RNA Activates APCs via TLR7/TLR8 While Virus Selectively Stimulates Macrophages Without Inducing Antiviral Responses.
Topics: Antigen-Presenting Cells; Cell Line; Chloroquine; HEK293 Cells; Hepacivirus; Hepatitis C; Humans; In | 2016 |
Association between porphyria cutanea tarda and beta-thalassemia major.
Topics: Adult; Anemia; beta-Thalassemia; Chloroquine; Deferoxamine; Female; Hepatitis C; Humans; Iron Overlo | 2009 |
Lysosomotropic agents as HCV entry inhibitors.
Topics: Ammonium Chloride; Antiviral Agents; Cell Line; Chloroquine; Hepacivirus; Hepatitis C; Humans; Lysos | 2011 |
A man with a blistering eruption and tuberculosis.
Topics: Antimalarials; Antitubercular Agents; Chloroquine; Diagnosis, Differential; Drug Therapy, Combinatio | 2012 |