chloroquine has been researched along with Hepatitis B Virus Infection in 11 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A severe flare-up of chronic hepatitis B infection with liver cell insufficiency has been observed in two patients after discontinuation of chloroquine administered either as malaria prophylaxis or as treatment of presumed rheumatoid arthritis." | 7.69 | [Reactivation of hepatitis B following withdrawal of chloroquine]. ( Helbling, B; Reichen, J, 1994) |
| "A severe flare-up of chronic hepatitis B infection with liver cell insufficiency has been observed in two patients after discontinuation of chloroquine administered either as malaria prophylaxis or as treatment of presumed rheumatoid arthritis." | 3.69 | [Reactivation of hepatitis B following withdrawal of chloroquine]. ( Helbling, B; Reichen, J, 1994) |
| " Preliminary results seem to indicate, that the dosage used may be reduced slowly and therapy finally stopped after 3-4 years of treatment in most patients." | 2.36 | [Therapy of chronic hepatitis (author's transl)]. ( Arnold, W; Meyer zum Büschenfelde, KH, 1981) |
| "Ethidium bromide was shown to be the strongest inhibitor among the compounds tested." | 1.26 | Inhibition of hepatitis B virus specific DNA polymerase by intercalating agents. ( Arnold, W; Gahl, GM; Hess, G; Meyer zum Büschenfelde, KH; Möller, B, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gochfeld, DJ | 1 |
| Hamann, MT | 1 |
| Zanati, SA | 1 |
| Locarnini, SA | 1 |
| Dowling, JP | 1 |
| Angus, PW | 1 |
| Dudley, FJ | 1 |
| Roberts, SK | 1 |
| Thomas, HC | 1 |
| Bassendine, MF | 1 |
| Arnold, W | 2 |
| Meyer zum Büschenfelde, KH | 2 |
| Hess, G | 1 |
| Möller, B | 1 |
| Gahl, GM | 1 |
| Reinis, M | 1 |
| Damková, M | 1 |
| Korec, E | 1 |
| Helbling, B | 1 |
| Reichen, J | 1 |
| Villarejos, VM | 1 |
| Rodriguez, AA | 1 |
| Gutierez, DA | 1 |
| Hirschman, SZ | 1 |
| Garfinkel, E | 1 |
| Penna, A | 1 |
| Fowler, P | 1 |
| Bertoletti, A | 1 |
| Guilhot, S | 1 |
| Moss, B | 1 |
| Margolskee, RF | 1 |
| Cavalli, A | 1 |
| Valli, A | 1 |
| Fiaccadori, F | 1 |
| Chisari, FV | 1 |
| Kouroumalis, EA | 1 |
| Koskinas, J | 1 |
2 reviews available for chloroquine and Hepatitis B Virus Infection
| Article | Year |
|---|---|
Immunological and anti-viral therapy of chronic hepatitis B virus infection.
Topics: Adjuvants, Immunologic; Antibody Formation; Antiviral Agents; Carcinoma, Hepatocellular; Chloroquine | 1980 |
[Therapy of chronic hepatitis (author's transl)].
Topics: Autoimmune Diseases; Azathioprine; Chloroquine; Chronic Disease; Diagnosis, Differential; Hepatitis; | 1981 |
9 other studies available for chloroquine and Hepatitis B Virus Infection
| Article | Year |
|---|---|
Isolation and biological evaluation of filiformin, plakortide F, and plakortone G from the Caribbean sponge Plakortis sp.
Topics: Animals; Antimalarials; Bromobenzenes; Chromatography, High Pressure Liquid; Colonic Neoplasms; Diox | 2001 |
Hepatic failure due to fibrosing cholestatic hepatitis in a patient with pre-surface mutant hepatitis B virus and mixed connective tissue disease treated with prednisolone and chloroquine.
Topics: Adult; Chloroquine; Cholestasis; Fatal Outcome; Female; Hepatitis B; Hepatitis B Surface Antigens; H | 2004 |
Inhibition of hepatitis B virus specific DNA polymerase by intercalating agents.
Topics: Carrier State; Chloroquine; DNA-Directed DNA Polymerase; Ethidium; Hepatitis B; Hepatitis B Antigens | 1980 |
Receptor-mediated transport of oligodeoxynucleotides into hepatic cells.
Topics: alpha-Fetoproteins; Asialoglycoprotein Receptor; Asialoglycoproteins; Base Sequence; Cell Line; Chlo | 1993 |
[Reactivation of hepatitis B following withdrawal of chloroquine].
Topics: Adult; Arthritis, Rheumatoid; Chloroquine; Female; Hepatitis B; Hepatitis B Core Antigens; Hepatitis | 1994 |
Letter: Chloroguine and HBs-Ag carrier status.
Topics: Carrier State; Chloroquine; Hepatitis B; Hepatitis B Antigens; Humans; Malaria; Radioimmunoassay | 1975 |
Inhibition of hepatitis B DNA polymerase by intercalating agents.
Topics: Chloroquine; Chlorpromazine; Drug Synergism; Ethidium; Hepatitis B; Hepatitis B virus; Humans; Indic | 1978 |
Hepatitis B virus (HBV)-specific cytotoxic T-cell (CTL) response in humans: characterization of HLA class II-restricted CTLs that recognize endogenously synthesized HBV envelope antigens.
Topics: Ammonium Chloride; Antigens, Viral; Antiviral Agents; Brefeldin A; CD4 Antigens; Chloroquine; Clone | 1992 |
Treatment of chronic active hepatitis B (CAH B) with chloroquine: a preliminary report.
Topics: Adult; Chloroquine; Female; Hepatitis B; Hepatitis B Antibodies; Hepatitis, Chronic; Humans; Male; M | 1986 |