chloroquine has been researched along with Grippe in 12 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pandemic influenza A H1N1/2009 vaccine response is diminished in SLE under immunosuppressive therapy and antimalarials seems to restore this immunogenicity." | 2.77 | Influenza A/H1N1 vaccination of patients with SLE: can antimalarial drugs restore diminished response under immunosuppressive therapy? ( Aikawa, NE; Bonfa, E; Borba, EF; Calich, AL; Costa, LP; Fuller, R; Goncalves, CR; Guedes, LK; Ishida, MA; Leon, EP; Moraes, JC; Oliveira, SA; Pasoto, SG; Precioso, AR; Ribeiro, AC; Saad, CG; Silva, CA, 2012) |
| "Chloroquine has in-vitro activity against influenza and could be an ideal candidate for worldwide prevention of influenza in the period between onset of a pandemic with a virulent influenza strain and the development and widespread dissemination of an effective vaccine." | 2.76 | Chloroquine for influenza prevention: a randomised, double-blind, placebo controlled trial. ( Archuleta, S; Cheung, YB; Lee, L; Ooi, EE; Paton, NI; Smith, AW; Wilder-Smith, A; Wong, G; Xu, Y, 2011) |
| "Limited treatment options for severe influenza pneumonia prioritize the need for the discovery of effective therapies." | 1.51 | IL-22Ra1 is induced during influenza infection by direct and indirect TLR3 induction of STAT1. ( Alcorn, JF; Cipriani, A; Hebert, KD; Mclaughlin, N; Pociask, DA; Zhang, Z, 2019) |
| "Avian influenza A H5N1 presents a serious and possibly imminent pandemic threat." | 1.35 | Confronting an influenza pandemic with inexpensive generic agents: can it be done? ( Fedson, DS, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hebert, KD | 1 |
| Mclaughlin, N | 1 |
| Zhang, Z | 1 |
| Cipriani, A | 1 |
| Alcorn, JF | 1 |
| Pociask, DA | 1 |
| Zhang, J | 1 |
| Zhang, W | 1 |
| Ren, L | 1 |
| He, Y | 1 |
| Mei, Z | 1 |
| Feng, J | 1 |
| Shi, T | 1 |
| Zhang, H | 1 |
| Song, Z | 1 |
| Jie, Z | 1 |
| Kang, Y | 1 |
| Chen, T | 1 |
| Mui, D | 1 |
| Ferrari, V | 1 |
| Jagasia, D | 1 |
| Scherrer-Crosbie, M | 1 |
| Chen, Y | 1 |
| Han, Y | 1 |
| Liu, W | 1 |
| Zhou, P | 1 |
| Chen, K | 1 |
| Ye, Z | 1 |
| Liu, F | 1 |
| Li, X | 1 |
| He, N | 1 |
| Wu, Z | 1 |
| Zhang, Q | 1 |
| Gong, X | 1 |
| Tang, Q | 1 |
| Du, X | 1 |
| Ying, Y | 1 |
| Xu, X | 1 |
| Zhang, Y | 1 |
| Liu, J | 1 |
| Li, Y | 1 |
| Shen, N | 1 |
| Couban, RJ | 1 |
| Ibrahim, QI | 1 |
| Guyatt, G | 1 |
| Zhai, S | 1 |
| Xu, Y | 2 |
| Lam, KF | 1 |
| Ooi, EE | 2 |
| Wilder-Smith, A | 2 |
| Paton, NI | 2 |
| Lee, LS | 1 |
| Cheung, YB | 2 |
| Lee, L | 1 |
| Archuleta, S | 1 |
| Wong, G | 1 |
| Smith, AW | 1 |
| Savarino, A | 1 |
| Borba, EF | 1 |
| Saad, CG | 1 |
| Pasoto, SG | 1 |
| Calich, AL | 1 |
| Aikawa, NE | 1 |
| Ribeiro, AC | 1 |
| Moraes, JC | 1 |
| Leon, EP | 1 |
| Costa, LP | 1 |
| Guedes, LK | 1 |
| Silva, CA | 1 |
| Goncalves, CR | 1 |
| Fuller, R | 1 |
| Oliveira, SA | 1 |
| Ishida, MA | 1 |
| Precioso, AR | 1 |
| Bonfa, E | 1 |
| SPENCE, HY | 1 |
| CASHMAN, JW | 1 |
| GALLAGHER, JA | 1 |
| MALANDRINI, F | 1 |
| PIERI, I | 1 |
| VEDOVINI, F | 1 |
| Fedson, DS | 1 |
| Eliassen, TM | 1 |
| Frøystad, MK | 1 |
| Dannevig, BH | 1 |
| Jankowska, M | 1 |
| Brech, A | 1 |
| Falk, K | 1 |
| Romøren, K | 1 |
| Gjøen, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised, Double-blind, Placebo Controlled Trial of Chloroquine for the Prevention of Influenza[NCT01078779] | Phase 2 | 1,516 participants (Actual) | Interventional | 2009-11-30 | Active, not recruiting | ||
| Immunogenicity and Safety of Influenza A/H3N2 Vaccine in Patients With Rheumatologic Diseases[NCT03540823] | Phase 4 | 300 participants (Actual) | Interventional | 2018-04-23 | Completed | ||
| Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases[NCT01151644] | Phase 4 | 5,000 participants (Anticipated) | Interventional | 2010-04-30 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for chloroquine and Grippe
| Article | Year |
|---|---|
Cardiovascular manifestations and treatment considerations in COVID-19.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inh | 2020 |
Efficacy and safety of antiviral treatment for COVID-19 from evidence in studies of SARS-CoV-2 and other acute viral infections: a systematic review and meta-analysis.
Topics: Amides; Antiviral Agents; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 D | 2020 |
2 trials available for chloroquine and Grippe
| Article | Year |
|---|---|
Chloroquine for influenza prevention: a randomised, double-blind, placebo controlled trial.
Topics: Adolescent; Adult; Antiviral Agents; Chloroquine; Double-Blind Method; Female; Hemagglutination Inhi | 2011 |
Influenza A/H1N1 vaccination of patients with SLE: can antimalarial drugs restore diminished response under immunosuppressive therapy?
Topics: Adult; Anti-Inflammatory Agents; Antimalarials; Chloroquine; Cohort Studies; Drug Therapy, Combinati | 2012 |
Influenza A/H1N1 vaccination of patients with SLE: can antimalarial drugs restore diminished response under immunosuppressive therapy?
Topics: Adult; Anti-Inflammatory Agents; Antimalarials; Chloroquine; Cohort Studies; Drug Therapy, Combinati | 2012 |
Influenza A/H1N1 vaccination of patients with SLE: can antimalarial drugs restore diminished response under immunosuppressive therapy?
Topics: Adult; Anti-Inflammatory Agents; Antimalarials; Chloroquine; Cohort Studies; Drug Therapy, Combinati | 2012 |
Influenza A/H1N1 vaccination of patients with SLE: can antimalarial drugs restore diminished response under immunosuppressive therapy?
Topics: Adult; Anti-Inflammatory Agents; Antimalarials; Chloroquine; Cohort Studies; Drug Therapy, Combinati | 2012 |
8 other studies available for chloroquine and Grippe
| Article | Year |
|---|---|
IL-22Ra1 is induced during influenza infection by direct and indirect TLR3 induction of STAT1.
Topics: A549 Cells; Animals; Chloroquine; Humans; Influenza, Human; Interferons; Male; Mice; Mice, Inbred C5 | 2019 |
Astragaloside IV attenuates IL-1β secretion by enhancing autophagy in H1N1 infection.
Topics: A549 Cells; Autophagosomes; Autophagy; Chloroquine; Humans; Influenza A Virus, H1N1 Subtype; Influen | 2020 |
A simple and powerful method for the estimation of intervention effects on serological endpoints using paired interval-censored data.
Topics: Antibodies, Viral; Antiviral Agents; Biomarkers; Chloroquine; Clinical Trials as Topic; Computer Sim | 2015 |
Use of chloroquine in viral diseases.
Topics: Antiviral Agents; Chloroquine; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H | 2011 |
PEACE CORPS HEALTH EXPERIENCES ABROAD.
Topics: Amebiasis; Chloroquine; Communicable Diseases; Dermatology; Dysentery; Dysentery, Amebic; Gastroente | 1963 |
[RESEARCH ON ACTION EXERCISED BY SOME ANTIRHEUMATIC PREPARATIONS ON FORMATION ANTI-INFLUENZA ANTIBODIES IN THE MOUSE].
Topics: Animals; Antibody Formation; Chloroquine; Humans; Influenza, Human; Mice; Phenylbutazone; Research; | 1963 |
Confronting an influenza pandemic with inexpensive generic agents: can it be done?
Topics: Antiviral Agents; Chloroquine; Disease Outbreaks; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Red | 2008 |
Initial events in infectious salmon anemia virus infection: evidence for the requirement of a low-pH step.
Topics: Ammonium Chloride; Anti-Bacterial Agents; Cell Line; Chloroquine; Cold Temperature; Cytopathogenic E | 2000 |